Get started
Author

Gianni Sava

Observed names: G SAVA, G Sava, G. SAVA, G. Sava, Prof Gianni Sava, SAVA, GIANNI, Sava, G., Sava, Gianni
Observed institutions: Leiden University, University of Trieste, University of Rijeka, University of Zagreb, Centre Hospitalier Universitaire Vaudois, University of Catania, Ruđer Bošković Institute, Società Italiana di Farmacologia, École Polytechnique Fédérale de Lausanne, University of Bari Aldo Moro
ORCID: 0000-0002-5138-6041
Observed ORCID: 0000-0002-5138-6041
OpenAlex ID: A5027632014
In Vitro and in Vivo Evaluation of Ruthenium(II)−Arene PTA Complexes
2005 · Claudine Scolaro, Alberta Bergamo, et al. · Journal of Medicinal Chemistry · 804
Metal-based antitumour drugs in the post genomic era
2006 · Paul J. Dyson, Gianni Sava · Dalton Transactions · 782
Approaching tumour therapy beyond platinum drugs
2011 · A. Bergamo, C. Gaiddon, et al. · Journal of Inorganic Biochemistry · 533
Ruthenium Antimetastatic Agents
2004 · Enzo Alessio, Giovanni Mestroni, et al. · Current Topics in Medicinal Chemistry · 483
Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs
2011 · Alberta Bergamo, Gianni Sava · Dalton Transactions · 454
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
2014 · Suzanne Leijen, Sjaak A. Burgers, et al. · Investigational New Drugs · 392
PDF
A review on usnic acid, an interesting natural compound
2002 · Moreno Cocchietto, Nicola Skert, et al. · Die Naturwissenschaften · 387
Organometallic ruthenium-based antitumor compounds with novel modes of action
2010 · Wee Han Ang, Angela Casini, et al. · Journal of Organometallic Chemistry · 373
Cis- and trans-dihalotetrakis(dimethyl sulfoxide)ruthenium(II) complexes (RuX2(DMSO)4; X = Cl, Br): synthesis, structure, and antitumor activity
1988 · Enzo Alessio, Giovanni Mestroni, et al. · Inorganic Chemistry · 339
Ruthenium complexes can target determinants of tumour malignancy
2007 · A. Bergamo, G. Sava · Dalton Transactions · 298
Metal-based antitumour drugs in the post-genomic era: what comes next?
2011 · Gianni Sava, Alberta Bergamo, et al. · Dalton Transactions · 234
Linking the future of anticancer metal-complexes to the therapy of tumour metastases
2015 · Alberta Bergamo, Gianni Sava · Chemical Society Reviews · 225
Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A
2002 · G Sava, A Bergamo, et al. · European Journal of Cancer · 222
Dual Action of NAMI-A in inhibition of solid tumor metastasis: selective targeting of metastatic cells and binding to collagen.
2003 · Gianni Sava, Sonia Zorzet, et al. · PubMed · 219
In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model
2009 · A. Bergamo, A. Masi, et al. · Journal of Inorganic Biochemistry · 190
Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex
1998 · G. Sava, I. Capozzi, et al. · Clinical & Experimental Metastasis · 189
Development of Ruthenium Antitumor Drugs that Overcome Multidrug Resistance Mechanisms
2007 · Carsten A. Vock, Wee Han Ang, et al. · Journal of Medicinal Chemistry · 188
The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation
2003 · Marina Bacac, Anna C.G Hotze, et al. · Journal of Inorganic Biochemistry · 174
In Vitro Cell Cycle Arrest, In Vivo Action on Solid Metastasizing Tumors, and Host Toxicity of the Antimetastatic Drug NAMI-A and Cisplatin
1999 · A. Bergamo, R. Gagliardi, et al. · Journal of Pharmacology and Experimental Therapeutics · 168
Influence of Hydrogen-Bonding Substituents on the Cytotoxicity of RAPTA Compounds
2005 · Claudine Scolaro, Tilmann J. Geldbach, et al. · Organometallics · 157
Tuning the hydrophobicity of ruthenium(ii)–arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy
2007 · Claudine Scolaro, Adrian B. Chaplin, et al. · Dalton Transactions · 153
Water‐Soluble Ruthenium(III)‐Dimethyl Sulfoxide Complexes:Chemical Behaviour and Pharmaceutical Properties
1993 · G. Mestroni, E. Alessio, et al. · Metal-Based Drugs · 152
PDF
Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA
2011 · Filipa Mendes, Michael Groessl, et al. · Journal of Medicinal Chemistry · 151
Synthesis, catalytic properties and biological activity of new water soluble ruthenium cyclopentadienyl PTA complexes [(C5R5)RuCl(PTA)2] (R = H, Me; PTA = 1,3,5-triaza-7-phosphaadamantane)Electronic supplementary information (ESI) available: synthesis, 31P{1H}, 1H, 13C NMR characterisation and elemental analysis of 1 and 2. See http://www.rsc.org/suppdata/cc/b2/b210102e/
2002 · Dina N. Akbayeva, Luca Gonsalvi, et al. · Chemical Communications · 147
Inhibition of endothelial cell functions and of angiogenesis by the metastasis inhibitor NAMI-A
2002 · A Vacca, M Bruno, et al. · British Journal of Cancer · 147
PDF
Works count: 333
Citation count: 14,410
H-index: 63
I10-index: 173
Year
Topic
Type