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Alexander Espinosa

Observed names: A Espinosa, Alexander C. Espinosa, Espinosa, Alexander Espinosa
ORCID: 0000-0003-1107-776X
Observed ORCID: 0000-0003-1107-776X
OpenAlex ID: A5027660378
Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway
2009 · Alexander Espinosa, Valerie Dardalhon, et al. · The Journal of Experimental Medicine · 313
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Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells
2018 · Harald Lund, Melanie Pieber, et al. · Nature Communications · 246
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The Sjogren’s Syndrome-Associated Autoantigen Ro52 Is an E3 Ligase That Regulates Proliferation and Cell Death
2006 · Alexander Espinosa, Wei Zhou, et al. · The Journal of Immunology · 184
The complexity of Sjögren's syndrome: Novel aspects on pathogenesis
2011 · Roland Jonsson, Petra Vogelsang, et al. · Immunology Letters · 175
Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors
2010 · Rowan Higgs, Elisa Lazzari, et al. · PLoS ONE · 144
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Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus
2005 · Karin Popovic, Monica Ek, et al. · Arthritis & Rheumatism · 142
Interferon-α Induces Up-regulation and Nuclear Translocation of the Ro52 Autoantigen as Detected by a Panel of Novel Ro52-specific Monoclonal Antibodies
2007 · Linn Strandberg, Aurelie Ambrosi, et al. · Journal of Clinical Immunology · 120
The Expression of BAFF Is Controlled by IRF Transcription Factors
2015 · Maria Sjöstrand, Alina Johansson, et al. · The Journal of Immunology · 107
Anti-Ro52 Autoantibodies from Patients with Sjögren's Syndrome Inhibit the Ro52 E3 Ligase Activity by Blocking the E3/E2 Interface
2011 · Alexander Espinosa, Janosch Hennig, et al. · Journal of Biological Chemistry · 90
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High Ro52 Expression in Spontaneous and UV-Induced Cutaneous Inflammation
2009 · Vilija Oke, Ismini Vassilaki, et al. · Journal of Investigative Dermatology · 74
IL ‐17: A new actor in IFN ‐driven systemic autoimmune diseases
2012 · Aurélie Ambrosi, Alexander Espinosa, et al. · European Journal of Immunology · 73
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Expression of the Immune Regulator Tripartite-Motif 21 Is Controlled by IFN Regulatory Factors
2013 · Maria Sjöstrand, Aurélie Ambrosi, et al. · The Journal of Immunology · 69
Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder
2022 · Soumitra Mohanty, Witchuda Kamolvit, et al. · Nature Communications · 54
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Structural, functional and immunologic characterization of folded subdomains in the Ro52 protein targeted in Sjögren's syndrome
2005 · Lars Ottosson, Janosch Hennig, et al. · Molecular Immunology · 51
Enhanced interferon regulatory factor 3 binding to the interleukin‐23p19 promoter correlates with enhanced interleukin‐23 expression in systemic lupus erythematosus
2011 · Siobhán Smith, Joan Nı´ Gabhann, et al. · Arthritis & Rheumatism · 39
Androgens Modulate the Immune Profile in a Mouse Model of Polycystic Ovary Syndrome
2024 · Sara Torstensson, Angelo Ascani, et al. · Advanced Science · 34
Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero
2020 · Malin Hedlund, Gudny Ella Thorlacius, et al. · RMD Open · 32
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E3 ubiquitin-protein ligase TRIM21-mediated lysine capture by UBE2E1 reveals substrate-targeting mode of a ubiquitin-conjugating E2
2019 · Madhanagopal Anandapadamanaban, Nikolaos C. Kyriakidis, et al. · Journal of Biological Chemistry · 32
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The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide
2008 · Alexander Espinosa, Vilija Oke, et al. · Experimental Cell Research · 28
Imiquimod induces ER stress and Ca 2+ influx independently of TLR7 and TLR8
2016 · William A. Nyberg, Alexander Espinosa · Biochemical and Biophysical Research Communications · 23
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The rheumatic disease-associated FAM167A-BLK locus encodes DIORA-1, a novel disordered protein expressed highly in bronchial epithelium and alveolar macrophages
2018 · L Mentlein, G E Thorlacius, et al. · Clinical & Experimental Immunology · 21
TRIM 21 is important in the early phase of inflammation in the imiquimod‐induced psoriasis‐like skin inflammation mouse model
2016 · Hanne Vinter, Ane Langkilde, et al. · Experimental Dermatology · 19
TRIM21 controls Toll‐like receptor 2 responses in bone‐marrow‐derived macrophages
2019 · Maria Sjöstrand, Berit Carow, et al. · Immunology · 17
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Interleukin 18 Receptor 1 expression distinguishes patients with multiple sclerosis
2010 · Alan Gillett, Melanie Thessen Hedreul, et al. · Multiple Sclerosis Journal · 17
miR‐31 regulates energy metabolism and is suppressed in T cells from patients with Sjögren's syndrome
2018 · Alina Johansson, William A Nyberg, et al. · European Journal of Immunology · 16
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Works count: 48
Citation count: 2,189
H-index: 21
I10-index: 28
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