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Ellen R. Langille

Observed names: Ellen Langille, Ellen R Langille, Langille, Ellen
Observed institutions: Mount Sinai Hospital, Dalhousie University, Mount Sinai Hospital, University of Toronto, Lunenfeld-Tanenbaum Research Institute, Sinai Health System
ORCID: 0000-0002-3616-3616
Observed ORCID: 0000-0002-3616-3616
OpenAlex ID: A5027725046
Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling
2020 · Sampath K. Loganathan, Krista Schleicher, et al. · Science · 283
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ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells
2017 · Nicole I. Park, Paul Guilhamon, et al. · Cell stem cell · 214
Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
2021 · Joel D. Pearson, Katherine Huang, et al. · Cancer Cell · 175
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ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells
2017 · Nicole I. Park, Paul Guilhamon, et al. · Cell stem cell · 62
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Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
2022 · Ellen Langille, Khalid N. Al-Zahrani, et al. · Cancer Discovery · 55
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
2024 · YiQing Lü, Tiffany Cho, et al. · Molecular Systems Biology · 24
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Altered heart rate regulation by the autonomic nervous system in mice lacking natriuretic peptide receptor C (NPR-C)
2017 · Motahareh Moghtadaei, Ellen Langille, et al. · Scientific Reports · 16
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Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
2023 · Hyeyeon Kim, Kazeera Aliar, et al. · Cell Reports · 7
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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
2022 · YiQing Lü, Tiffany Cho, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 6
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In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
2020 · Sampath Kumar Loganathan, Ahmad Malik, et al. · Journal of Visualized Experiments · 6
Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes
2025 · Liis Uusküla-Reimand, Christian A. Lee, et al. · Nature Communications · 5
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Aneuploidy selects for the acquisition of driver genes in breast cancer
2026 · Khalid N. Al-Zahrani, Ellen R. Langille, et al. · Nature · 3
Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
2023 · Hyeyeon Kim, Kazeera Aliar, et al. · Cell Reports · 3
Loss of epigenetic regulation disrupts lineage integrity, reactivates multipotency and promotes breast cancer
2021 · Ellen R. Langille, Khalid N. Al-Zahrani, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
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Data from Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
2023 · Ellen Langille, Khalid N. Al-Zahrani, et al. · 1
Supplementary Data from Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
2023 · Ellen Langille, Khalid N. Al-Zahrani, et al. · 1
In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
2020 · Sampath Kumar Loganathan, Ahmad Malik, et al. · Journal of Visualized Experiments · 1
Functional identification of non-coding regulatory regions that drive breast and skin carcinogenesis
2026 · Robin H. Oh, Kevin C.L. Cheng, et al. · Cell Reports
Parallel In Vivo Screening of Gene Knockout and Activation in the Mouse Mammary Gland
2026 · Ellen R. Langille, Khalid N. Al-Zahrani, et al. · Journal of Visualized Experiments
Abstract 520: Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes.
2026 · Liis Uuskula-Reimand, Christian A. Lee, et al. · Cancer Research
Abstract 2780: Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes
2025 · Jüri Reimand, Christian A. Lee, et al. · Cancer Research
Abstract A022: Decoding aneuploidy: Identifying drivers and therapeutic targets in recurrent breast cancer copy number alterations
2025 · Khalid N Al-Zahrani, Ellen R Langille, et al. · Cancer Research
In vivo Screening Reveals Epigenetic Regulation of Mammary Epithelial Lineage Integrity and Tumorigenesis
2023 · Langille, Ellen · TSpace (University of Toronto)
Data from Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
2023 · Ellen Langille, Khalid N. Al-Zahrani, et al.
Supplementary Data from Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer
2023 · Ellen Langille, Khalid N. Al-Zahrani, et al.
Works count: 39
Citation count: 865
H-index: 7
I10-index: 7
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