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Simon L. Goodman

Observed names: Goodman, S, Goodman, S.L., S GOODMAN, S Goodman, S L Goodman, S. GOODMAN, S. Goodman, S. L. GOODMAN, S. L. Goodman, S.L. Goodman, SIMON L. GOODMAN, Simon Goodman, Simon L Goodman, Simon. L. Goodman, Simon L. Goodman
Observed institutions: Harvard University, Max Planck Society, University of Sussex, Merck KGaA, Darmstadt (Germany), Friedrich-Alexander-Universität Erlangen-Nürnberg, Aarhus University, Heidelberg University, Rigshospitalet, Christian-Albrechts-Universität zu Kiel, Humboldt-Universität zu Berlin, Massachusetts General Hospital, Universitätsklinikum Erlangen, Comprehensive Cancer Center Vienna, University Hospital Zurich, National Center for Tumor Diseases, Max Planck Institute for Developmental Biology, Kerckhoff Klinik, Friedrich Miescher Laboratory, Max Planck Institute of Biochemistry, Max Planck Institute of Immunobiology and Epigenetics, Merck Healthcare KGaA, Darmstadt (Germany), Technical University of Munich, Medical University of Vienna, University of Tübingen, Icahn School of Medicine at Mount Sinai
ORCID: 0000-0002-3480-1346
Observed ORCID: 0000-0002-3480-1346
OpenAlex ID: A5027735621
Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand
2002 · Jian-Ping Xiong, Thilo Stehle, et al. · Science · 1,650
Crystal Structure of the Extracellular Segment of Integrin αVβ3
2001 · Jian-Ping Xiong, Thilo Stehle, et al. · Science · 1,307
N -Methylated Cyclic RGD Peptides as Highly Active and Selective α V β 3 Integrin Antagonists
1999 · Michael A. Dechantsreiter, Eckart Planker, et al. · Journal of Medicinal Chemistry · 856
Structural and Functional Aspects of RGD-Containing Cyclic Pentapeptides as Highly Potent and Selective Integrin αVβ3Antagonists
1996 · Roland Haubner, Rainer Gratias, et al. · Journal of the American Chemical Society · 597
Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography.
2001 · R Haubner, H J Wester, et al. · PubMed · 557
Structure and mechanics of integrin-based cell adhesion
2007 · M Amin Arnaout, Simon L Goodman, et al. · Current Opinion in Cell Biology · 411
Integrins as therapeutic targets
2012 · Simon L. Goodman, Martin Picard · Trends in Pharmacological Sciences · 383
Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics.
2001 · R Haubner, H J Wester, et al. · PubMed · 379
Surface Coating with Cyclic RGD Peptides Stimulates Osteoblast Adhesion and Proliferation as well as Bone Formation
2000 · Martin Kantlehner, Patricia Schaffner, et al. · ChemBioChem · 327
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Decreased angiogenesis and arthritic disease in rabbits treated with an αvβ3 antagonist
1999 · Chris M. Storgard, Dwayne G. Stupack, et al. · Journal of Clinical Investigation · 309
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Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin.
1985 · J Behrens, W Birchmeier, et al. · The Journal of Cell Biology · 280
Multimeric Cyclic RGD Peptides as Potential Tools for Tumor Targeting: Solid‐Phase Peptide Synthesis and Chemoselective Oxime Ligation
2003 · Georgette Thumshirn, Ulrich Hersel, et al. · Chemistry - A European Journal · 273
Invasion patterns in brain metastases of solid cancers
2013 · Anna S. Berghoff, Orsolya Rajky, et al. · Neuro-Oncology · 256
Integrins as Therapeutic Targets: Successes and Cancers
2017 · Sabine Raab-Westphal, John Marshall, et al. · Cancers · 251
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Plasminogen Activator Inhibitor-1 Represses Integrin- and Vitronectin-Mediated Cell Migration Independently of Its Function as an Inhibitor of Plasminogen Activation
1997 · Lars Kjøller, Sandip M. Kanse, et al. · Experimental Cell Research · 238
Laminin alters cell shape and stimulates motility and proliferation of murine skeletal myoblasts
1988 · Mücella Öcalan, Simon L. Goodman, et al. · Developmental Biology · 211
αvβ3 and αvβ5 integrin antagonists inhibit angiogenesis in vitro
2003 · Riccardo E. Nisato, Jean-Christophe Tille, et al. · Angiogenesis · 206
New insights into the structural basis of integrin activation
2003 · Jian-Ping Xiong, Thilo Stehle, et al. · Blood · 206
Inhibition of Integrin αvβ6 on Cholangiocytes Blocks Transforming Growth Factor-β Activation and Retards Biliary Fibrosis Progression
2008 · Eleonora Patsenker, Yury Popov, et al. · Gastroenterology · 205
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Nanomolar Small Molecule Inhibitors for αvβ6, αvβ5, and αvβ3 Integrins
2002 · Simon L. Goodman, Günter Hölzemann, et al. · Journal of Medicinal Chemistry · 200
Coming to grips with integrin binding to ligands
2002 · M.Amin Arnaout, Simon L Goodman, et al. · Current Opinion in Cell Biology · 196
Two distinct cell-binding domains in laminin can independently promote nonneuronal cell adhesion and spreading [published erratum appears in J Cell Biol 1989 Jun;108(6):following 2546]
1987 · S. L. Goodman · The Journal of Cell Biology · 194
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Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin
2005 · Brian D. Adair, Jian-Ping Xiong, et al. · The Journal of Cell Biology · 191
The E8 subfragment of laminin promotes locomotion of myoblasts over extracellular matrix.
1989 · S L Goodman, G Risse, et al. · The Journal of Cell Biology · 191
In vivo therapy of malignant melanoma by means of antagonists of αv integrins
2000 · Francesc Mitjans, Tim Meyer, et al. · International Journal of Cancer · 182
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Works count: 151
Citation count: 15,660
H-index: 61
I10-index: 103
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