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Hanna Laudon

Lecanemab, Aducanumab, and Gantenerumab — Binding Profiles to Different Forms of Amyloid-Beta Might Explain Efficacy and Side Effects in Clinical Trials for Alzheimer's Disease
2022 · Linda Söderberg, Malin Johannesson, et al. · Neurotherapeutics · 443
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The Murine Version of BAN2401 (mAb158) Selectively Reduces Amyloid-β Protofibrils in Brain and Cerebrospinal Fluid of tg-ArcSwe Mice
2014 · Stina Tucker, Christer Möller, et al. · Journal of Alzheimer s Disease · 274
A Nine-transmembrane Domain Topology for Presenilin 1
2005 · Hanna Laudon, Emil M. Hansson, et al. · Journal of Biological Chemistry · 201
Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody
2018 · Stina Syvänen, Greta Hultqvist, et al. · Alzheimer s Research & Therapy · 83
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Presenilin-1 Mutation L271V Results in Altered Exon 8 Splicing and Alzheimer's Disease with Non-cored Plaques and No Neuritic Dystrophy
2003 · John B.J. Kwok, Glenda M. Halliday, et al. · Journal of Biological Chemistry · 56
Amyloid β Pathology in Alzheimer’s Disease and Schizophrenia
2003 · Dorota Religa, Hanna Laudon, et al. · American Journal of Psychiatry · 52
Co‐expressed presenilin 1 NTF and CTF form functional γ‐secretase complexes in cells devoid of full‐length protein
2004 · Hanna Laudon, Paul M. Mathews, et al. · Journal of Neurochemistry · 48
The Extreme C Terminus of Presenilin 1 Is Essential for γ-Secretase Complex Assembly and Activity
2004 · Anna Bergman, Hanna Laudon, et al. · Journal of Biological Chemistry · 44
Long-term effects of immunotherapy with a brain penetrating Aβ antibody in a mouse model of Alzheimer’s disease
2023 · Tobias Gustavsson, Nicole G. Metzendorf, et al. · Alzheimer s Research & Therapy · 35
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Deducing the Transmembrane Domain Organization of Presenilin-1 in γ-Secretase by Cysteine Disulfide Cross-Linking
2006 · Anna Y. Kornilova, Jennifer Kim, et al. · Biochemistry · 30
APP intracellular domain formation and unaltered signaling in the presence of familial Alzheimer’s disease mutations
2003 · Anna Bergman, Dorota Religa, et al. · Experimental Cell Research · 27
Standardized Preclinical In Vitro Blood–Brain Barrier Mouse Assay Validates Endocytosis-Dependent Antibody Transcytosis Using Transferrin-Receptor-Mediated Pathways
2023 · Jamie I. Morrison, Alex Petrovic, et al. · Molecular Pharmaceutics · 23
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The Alzheimer's disease-associated γ-secretase complex: Functional domains in the presenilin 1 protein
2007 · Hanna Laudon, Bengt Winblad, et al. · Physiology & Behavior · 20
γ‐Secretase complexes containing N‐ and C‐terminal fragments of different presenilin origin retain normal γ‐secretase activity
2005 · Kia Strömberg, Emil M. Hansson, et al. · Journal of Neurochemistry · 18
Functional Domains in Presenilin 1
2004 · Hanna Laudon, Helena Karlström, et al. · Journal of Biological Chemistry · 17
Caspase cleaved presenilin‐1 is part of active γ‐secretase complexes
2006 · Camilla A. Hansson, Bogdan O. Popescu, et al. · Journal of Neurochemistry · 16
The Large Hydrophilic Loop of Presenilin 1 Is Important for Regulating γ-Secretase Complex Assembly and Dictating the Amyloid β Peptide (Aβ) Profile without Affecting Notch Processing
2010 · Johanna Wanngren, Jenny Frånberg, et al. · Journal of Biological Chemistry · 15
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P4‐704: Ban2401 Shows Stronger Binding to Soluble Aggregated Amyloid‐beta Species Than Aducanumab
2019 · Lars Lannfelt, Linda Söderberg, et al. · Alzheimer s & Dementia · 14
A standardised pre-clinical in-vitro blood-brain barrier mouse assay validates endocytosis dependent antibody transcytosis using transferrin receptor-mediated pathways
2022 · Jamie I. Morrison, Alex Petrovic, et al. · Research Square · 3
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A standardised pre-clinical in-vitro blood-brain barrier mouse assay validates endocytosis dependent antibody transcytosis using transferrin receptor-mediated pathways.
2022 · Jamie I. Morrison, Alex Petrovic, et al. · Research Square
Efficient clearance of Amyloid-beta protofibrils in APP-transgenic mice treated with a brain penetrating bifunctional antibody
2017 · Dag Sehlin, Greta Hultqvist, et al. · Journal of Cerebral Blood Flow & Metabolism
S2–03–01: Molecular studies on the Alzheimer's presenilin protein
2006 · Helena Karlstrom, Hanna Laudon, et al. · Alzheimer s & Dementia
P3–396: Catalytic engine of γ–secretase consists of two separate pairs of aspartates: A cysteine disulfide crosslinking study
2006 · Hanna Laudon, Anna Y. Kornilova, et al. · Alzheimer s & Dementia
Functional domains in the Alzheimer�s disease-associated presenilin 1 protein
2004 · Hanna Laudon
P4-297 Functional domains in presenilin 1: the TYR-288 residue controls gamma-secretas activity and endoproteolysis
2004 · Hanna Laudon, Helena Karlstöm, et al. · Neurobiology of Aging
Works count: 29
Citation count: 1,419
H-index: 16
I10-index: 18
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