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Matthew T. O’Neill
Observed names:
Matthew O'Neill,
Matthew O’Neill,
Matthew T O'Neill,
Matthew T O’Neill,
Matthew T. O'Neill
Institutions:
The University of Melbourne,
Walter and Eliza Hall Institute of Medical Research,
Peter Doherty Institute
Observed institutions:
The University of Melbourne,
Walter and Eliza Hall Institute of Medical Research,
Peter Doherty Institute
ORCID:
0000-0001-5185-8603
Observed ORCID:
0000-0001-5185-8603
OpenAlex ID:
A5027960774
Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes
2008
·
Alexander G. Maier
, Melanie Rug
, et al.
·
Cell
·
529
PDF
Type II fatty acid synthesis is essential only for malaria parasite late liver stage development
2008
·
Ashley M. Vaughan
, Matthew T. O'Neill
, et al.
·
Cellular Microbiology
·
411
PDF
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design
2009
·
Kelley M. VanBuskirk
, Matthew T. O'Neill
, et al.
·
Proceedings of the National Academy of Sciences
·
172
Skeleton-binding protein 1 functions at the parasitophorous vacuole membrane to traffic PfEMP1 to the Plasmodium falciparum–infected erythrocyte surface
2006
·
Alexander G. Maier
, Melanie Rug
, et al.
·
Blood
·
169
PDF
An EGF-like Protein Forms a Complex with PfRh5 and Is Required for Invasion of Human Erythrocytes by Plasmodium falciparum
2011
·
Lin Chen
, Sash Lopaticki
, et al.
·
PLoS Pathogens
·
159
PDF
Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites
2014
·
Brad E. Sleebs
, Sash Lopaticki
, et al.
·
PLoS Biology
·
155
PDF
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers
2013
·
Michele Spring
, Jittawadee Murphy
, et al.
·
Vaccine
·
143
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice
2021
·
Phillip Pymm
, Amy Adair
, et al.
·
Proceedings of the National Academy of Sciences
·
137
Conditional expression of apical membrane antigen 1 in P lasmodium falciparum shows it is required for erythrocyte invasion by merozoites
2014
·
Alan Yap
, Mauro F. Azevedo
, et al.
·
Cellular Microbiology
·
122
PDF
VAR2CSA is the principal ligand for chondroitin sulfate A in two allogeneic isolates of Plasmodium falciparum
2006
·
Michael F. Duffy
, Alexander G. Maier
, et al.
·
Molecular and Biochemical Parasitology
·
116
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell
2015
·
Michael J Coffey
, Brad E Sleebs
, et al.
·
eLife
·
113
Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes
2015
·
Anthony N Hodder
, Brad E Sleebs
, et al.
·
Nature Structural & Molecular Biology
·
102
Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice
2017
·
Annie S.P. Yang
, Matthew T. O’Neill
, et al.
·
Cell Reports
·
100
PDF
A Set of Glycosylphosphatidyl Inositol-Anchored Membrane Proteins ofPlasmodium falciparumIs Refractory to Genetic Deletion
2006
·
Paul R. Sanders
, Lev M. Kats
, et al.
·
Infection and Immunity
·
94
A Next-generation Genetically Attenuated Plasmodium falciparum Parasite Created by Triple Gene Deletion
2014
·
Sebastian A Mikolajczak
, Viswanathan Lakshmanan
, et al.
·
Molecular Therapy
·
90
PDF
AMA1 and MAEBL are important forPlasmodium falciparumsporozoite infection of the liver
2017
·
Annie S. P. Yang
, Sash Lopaticki
, et al.
·
Cellular Microbiology
·
88
PDF
Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton
2014
·
Melanie Rug
, Marek Cyrklaff
, et al.
·
Blood
·
88
PDF
Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts
2017
·
Sash Lopaticki
, Annie S. P. Yang
, et al.
·
Nature Communications
·
75
PDF
Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding
2016
·
Justin A. Boddey
, Matthew T. O’Neill
, et al.
·
Nature Communications
·
70
PDF
Gene deletion from Plasmodium falciparum using FLP and Cre recombinases: Implications for applied site-specific recombination
2010
·
Matthew T. O’Neill
, Thuan Phuong
, et al.
·
International Journal for Parasitology
·
60
Transition State Mimetics of the Plasmodium Export Element Are Potent Inhibitors of Plasmepsin V from P. falciparum and P. vivax
2014
·
Brad E. Sleebs
, Michelle Gazdik
, et al.
·
Journal of Medicinal Chemistry
·
57
Rapid detection of monkeypox virus using a CRISPR-Cas12a mediated assay: a laboratory validation and evaluation study
2023
·
Soo Jen Low
, Matthew T O'Neill
, et al.
·
The Lancet Microbe
·
49
PDF
Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P 2 position of PEXEL peptidomimetics
2018
·
William Nguyen
, Anthony N. Hodder
, et al.
·
European Journal of Medicinal Chemistry
·
49
Plasmodium falciparum PF10_0164 (ETRAMP10.3) Is an Essential Parasitophorous Vacuole and Exported Protein in Blood Stages
2010
·
Drew C. MacKellar
, Matthew T. O'Neill
, et al.
·
Eukaryotic Cell
·
47
Inhibition of Plasmepsin V Activity Blocks Plasmodium falciparum Gametocytogenesis and Transmission to Mosquitoes
2019
·
Charlie Jennison
, Leonardo Lucantoni
, et al.
·
Cell Reports
·
44
PDF
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Works count:
45
Citation count:
3,497
H-index:
27
I10-index:
35
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