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Tianlun Zhou

Characterization of the Intracellular Deproteinized Relaxed Circular DNA of Hepatitis B Virus: an Intermediate of Covalently Closed Circular DNA Formation
2007 · Haitao Guo, Dong Jiang, et al. · Journal of Virology · 350
Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1.
1995 · K A McGlynn, E A Rosvold, et al. · Proceedings of the National Academy of Sciences · 278
Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
2015 · Qi Fei, Ke Shang, et al. · Nature Communications · 176
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Regulation of Hepatitis B Virus Replication by the Phosphatidylinositol 3-Kinase-Akt Signal Transduction Pathway
2007 · Haitao Guo, Tianlun Zhou, et al. · Journal of Virology · 148
Hepatitis B virus e antigen production is dependent upon covalently closed circular (ccc) DNA in HepAD38 cell cultures and may serve as a cccDNA surrogate in antiviral screening assays
2006 · Tianlun Zhou, Haitao Guo, et al. · Antiviral Research · 111
Emergence of Drug-Resistant Populations of Woodchuck Hepatitis Virus in Woodchucks Treated with the Antiviral Nucleoside Lamivudine
1999 · Tianlun Zhou, Jeffry Saputelli, et al. · Antimicrobial Agents and Chemotherapy · 86
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Low frequency of p53 mutations observed in a diverse collection of primary hepatocellular carcinomas.
1992 · K H Buetow, V C Sheffield, et al. · Proceedings of the National Academy of Sciences · 83
Activation of Stimulator of Interferon Genes in Hepatocytes Suppresses the Replication of Hepatitis B Virus
2017 · Fang Guo, Liudi Tang, et al. · Antimicrobial Agents and Chemotherapy · 78
Characterization of the Host Factors Required for Hepadnavirus Covalently Closed Circular (ccc) DNA Formation
2012 · Haitao Guo, Chunxiao Xu, et al. · PLoS ONE · 64
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Virological Basis for the Cure of Chronic Hepatitis B
2018 · Jin Hu, Junjun Cheng, et al. · ACS Infectious Diseases · 60
Glutathione S-transferase expression in hepatitis B virus-associated human hepatocellular carcinogenesis.
1997 · T Zhou, A A Evans, et al. · PubMed · 57
HBsAg mRNA degradation induced by a dihydroquinolizinone compound depends on the HBV posttranscriptional regulatory element
2017 · Tianlun Zhou, Timothy Block, et al. · Antiviral Research · 49
The liver of woodchucks chronically infected with the woodchuck hepatitis virus contains foci of virus core antigen-negative hepatocytes with both altered and normal morphology
2006 · Chunxiao Xu, Toshiki Yamamoto, et al. · Virology · 34
Mutations of the Woodchuck Hepatitis Virus Polymerase Gene That Confer Resistance to Lamivudine and 2′-Fluoro-5-Methyl-β- l -Arabinofuranosyluracil
2002 · Toshiki Yamamoto, Samuel Litwin, et al. · Journal of Virology · 33
Combination Therapy with Lamivudine and Adenovirus Causes Transient Suppression of Chronic Woodchuck Hepatitis Virus Infections
2000 · Tianlun Zhou, Juo-Tao Guo, et al. · Journal of Virology · 33
Hepatitis B virus nucleocapsid uncoating: biological consequences and regulation by cellular nucleases
2021 · Jin Hu, Liudi Tang, et al. · Emerging Microbes & Infections · 32
The Dihydroquinolizinone Compound RG7834 Inhibits the Polyadenylase Function of PAPD5 and PAPD7 and Accelerates the Degradation of Matured Hepatitis B Virus Surface Protein mRNA
2020 · Liren Sun, Fang Zhang, et al. · Antimicrobial Agents and Chemotherapy · 29
Discovery and Characterization of RP03707: A Highly Potent and Selective KRAS G12D PROTAC
2025 · Xiang Ji, Huanping Li, et al. · Journal of Medicinal Chemistry · 28
Hepatitis B Virus Large and Middle Glycoproteins Are Degraded by a Proteasome Pathway in Glucosidase-Inhibited Cells but Not in Cells with Functional Glucosidase Enzyme
2005 · Ender Simsek, Anand Mehta, et al. · Journal of Virology · 22
Hepatoselective Dihydroquinolizinone Bis-acids for HBsAg mRNA Degradation
2021 · Nicky Hwang, Liren Sun, et al. · ACS Medicinal Chemistry Letters · 19
A Putative Amphipathic Alpha Helix in Hepatitis B Virus Small Envelope Protein Plays a Critical Role in the Morphogenesis of Subviral Particles
2021 · Sisi Yang, Zhongliang Shen, et al. · Journal of Virology · 19
Molecular and genetic epidemiology of hepatocellular carcinoma: studies in China and Senegal.
1995 · W T London, A A Evans, et al. · PubMed · 19
“PROTAC” modified dihydroquinolizinones (DHQs) that cause degradation of PAPD-5 and inhibition of hepatitis A virus and hepatitis B virus, in vitro
2024 · You Li, Nicky Hwang, et al. · Bioorganic & Medicinal Chemistry Letters · 18
Rapid and sensitive detection of hepatitis B virus 1762T/1764A double mutation from hepatocellular carcinomas using LNA-mediated PCR clamping and hybridization probes
2009 · Xiangdong David Ren, Selena Y. Lin, et al. · Journal of Virological Methods · 18
The role of the downstream signal sequences in the maturation of the HBV middle surface glycoprotein: Development of a novel therapeutic vaccine candidate
2007 · Yuanjie Liu, Ender Simsek, et al. · Virology · 13
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Works count: 47
Citation count: 1,943
H-index: 19
I10-index: 29
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