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Juan A. Hernández Bort

Observed names: J.A. Hernandez Bort, Juan A. Hernandez Bort, Juan A.Hernandez Bort, Juan Hernandez Bort, Juan Hernández Bort
Observed institutions: Institute of Molecular Biotechnology, University of Vienna, Hochschule Campus Wien, Baxalta (United States), Austrian Centre of Industrial Biotechnology (Austria), Takeda (Austria), BOKU University
ORCID: 0000-0003-2348-4864
Observed ORCID: 0000-0003-2348-4864
OpenAlex ID: A5027981319
Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering
2011 · Matthias Hackl, Tobias Jakobi, et al. · Journal of Biotechnology · 114
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Dynamic mRNA and miRNA profiling of CHO‐K1 suspension cell cultures
2011 · Juan A. Hernández Bort, Matthias Hackl, et al. · Biotechnology Journal · 94
Stable overexpression of miR-17 enhances recombinant protein production of CHO cells
2014 · Vaibhav Jadhav, Matthias Hackl, et al. · Journal of Biotechnology · 84
Utilization and evaluation of CHO‐specific sequence databases for mass spectrometry based proteomics
2012 · Paula Meleady, Raimund Hoffrogge, et al. · Biotechnology and Bioengineering · 62
A screening method to assess biological effects of microRNA overexpression in Chinese hamster ovary cells
2012 · Vaibhav Jadhav, Matthias Hackl, et al. · Biotechnology and Bioengineering · 60
Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth
2011 · Michael Taschwer, Matthias Hackl, et al. · Journal of Biotechnology · 54
CHO‐K1 host cells adapted to growth in glutamine‐free medium by FACS‐assisted evolution
2010 · Juan A. Hernández Bort, Beate Stern, et al. · Biotechnology Journal · 45
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
2021 · Karen Julie la Cour Karottki, Hooman Hefzi, et al. · Metabolic Engineering · 38
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Assessment of the percentage of full recombinant adeno-associated virus particles in a gene therapy drug using CryoTEM
2022 · Mathieu Colomb-Delsuc, Roman Raim, et al. · PLoS ONE · 25
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Reduced quenching and extraction time for mammalian cells using filtration and syringe extraction
2014 · Juan A. Hernández Bort, Vinoth Shanmukam, et al. · Journal of Biotechnology · 25
A signature of 12 microRNAs is robustly associated with growth rate in a variety of CHO cell lines
2016 · Gerald Klanert, Vaibhav Jadhav, et al. · Journal of Biotechnology · 19
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Crucial aspects for maintaining rAAV stability
2024 · Johannes Lengler, Mia Gavrila, et al. · Scientific Reports · 18
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Comprehensive mRNA‐sequencing‐based characterization of three HEK‐293 cell lines during an rAAV production process for gene therapy applications
2023 · Martina Pistek, Carolin‐Isabel Kahlig, et al. · Biotechnology Journal · 18
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Enhancement of rAAV titers via inhibition of the interferon signaling cascade in transfected HEK293 suspension cultures
2024 · Carolin‐Isabel Kahlig, Sylvain Moser, et al. · Biotechnology Journal · 13
Multi-omics driven genome-scale metabolic modeling improves viral vector yield in HEK293
2025 · L. Zehetner, D. Széliová, et al. · Metabolic Engineering · 9
Orthogonal characterization of rAAV9 reveals unexpected transgene heterogeneity
2024 · Peter Eisenhut, Peter Andorfer, et al. · Journal of Biotechnology · 9
Factors affecting rAAV titers during triple-plasmid transient transfection in HEK-293 cells
2024 · Martina Pistek, Peter Andorfer, et al. · Biotechnology Letters · 8
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Scaling strategy for cell and gene therapy bioreactors based on turbulent parameters
2023 · Dmytro Iurashev, Peter Anthony Jones, et al. · Biotechnology Journal · 8
Optimizing VLP production in gene therapy: Opportunities and challenges for in silico modeling
2023 · Leopold Zehetner, Diana Széliová, et al. · Biotechnology Journal · 8
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Proton-transfer-reaction mass spectrometry (PTR-MS) for online monitoring of glucose depletion and cell concentrations in HEK 293 gene therapy processes
2021 · Benjamin Bayer, Andreas Maccani, et al. · Biotechnology Letters · 6
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Logistic PCA explains differences between genome-scale metabolic models in terms of metabolic pathways
2024 · Leopold Zehetner, Diana Széliová, et al. · PLoS Computational Biology · 5
Cas‐CLOVER‐mediated knockout of STAT1: A novel approach to engineer packaging HEK‐293 cell lines used for rAAV production
2024 · Peter Andorfer, Carolin‐Isabel Kahlig, et al. · Biotechnology Journal · 3
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Characterizing the Biopotency of Truncated Transgene Variants in rAAV8 viral vectors: Essential Considerations for Gene Therapy Applications
2024 · Christian Fiedler, Johannes Lengler, et al. · Research Square
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Works count: 23
Citation count: 725
H-index: 13
I10-index: 14
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