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Thijs MP van Iersel

Observed names: T. Iersel, T. van Iersel, T.V. Iersel, Thijs van Iersel, van Iersel, Thijs
Observed institutions: University Medical Center Groningen, QPS (Netherlands), MSD (Netherlands), Xendo (Netherlands), ICON PLC (Ireland), Organon (Netherlands), Amsterdam UMC Location Vrije Universiteit Amsterdam, PRA Health Sciences
ORCID: 0000-0002-5754-6165
Observed ORCID: 0000-0002-5754-6165
OpenAlex ID: A5028016060
First Human Exposure of Org 25969, a Novel Agent to Reverse the Action of Rocuronium Bromide
2005 · Francois Gijsenbergh, Steven Ramael, et al. · Anesthesiology · 306
Acute and 2-week exposure to prednisolone impair different aspects of β-cell function in healthy men
2010 · Daniël H van Raalte, Valentina Nofrate, et al. · European Journal of Endocrinology · 176
Safety and tolerability of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11)
2009 · Walter JFM van der Velden, Thijs MP van Iersel, et al. · BMC Medicine · 124
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Safety, Tolerability and Pharmacokinetics of Sugammadex Using Single High Doses (Up to 96 mg/kg) in Healthy Adult Subjects
2010 · Pierre A. M. Peeters, Michiel W. van den Heuvel, et al. · Clinical Drug Investigation · 76
Pharmacokinetics and Safety Study of Posaconazole Intravenous Solution Administered Peripherally to Healthy Subjects
2014 · Wendy M. Kersemaekers, Thijs van Iersel, et al. · Antimicrobial Agents and Chemotherapy · 67
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A Phase I Study to Assess the Effect of Speed of Injection on Pain, Tolerability, and Pharmacokinetics After High-volume Subcutaneous Administration of Gantenerumab in Healthy Volunteers
2019 · Agnès Portron, Paul Jordan, et al. · Clinical Therapeutics · 44
Application of dried blood spot sampling combined with LC‐MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers
2011 · Theo de Boer, Jaap Wieling, et al. · Biomedical Chromatography · 32
Absence of Excretion of the Active Moiety of Bisacodyl and Sodium Picosulfate into Human Breast Milk: an Open-label Parallel-group, Multiple-dose Study in Healthy Lactating Women
2011 · Christian Friedrich, Erika Richter, et al. · Drug Metabolism and Pharmacokinetics · 31
Phase I study of Solulin, a novel recombinant soluble human thrombomodulin analogue
2010 · Thijs van Iersel, Heimo Stroissnig, et al. · Thrombosis and Haemostasis · 27
Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling
2012 · Sandrine Ellero-Simatos, Ewa Szymańska, et al. · Genome Medicine · 19
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Similar Pharmacokinetics of the Adalimumab (Humira®) Biosimilar BI 695501 Whether Administered via Subcutaneous Autoinjector or Prefilled Syringe (VOLTAIRE®-AI and VOLTAIRE®-TAI): Phase 1, Randomized, Open-Label, Parallel-Group Trials
2018 · Steven Ramael, Benjamin Van Hoorick, et al. · Rheumatology and Therapy · 18
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The Patient Motivation Pyramid and Patient-Centricity in Early Clinical Development
2021 · Thijs van Iersel, Jocelyn Courville, et al. · Current Clinical Pharmacology · 8
Phase 1 Safety and Tolerability Study of Imb-1018972, a Novel Oral Modulator of Myocardial Substrate Utilization Designed to Improve Cardiac Metabolic Efficiency and Bioenergetics
2021 · Paul Chamberlin, Lisa Barrett, et al. · Journal of the American College of Cardiology · 6
Preliminary Assessment of Org 25969 as a Reversal Agent for Rocuronium in Healthy Male Volunteers
2002 · Francois Gijsenbergh, Steven Ramael, et al. · Anesthesiology · 6
Healthy participant engagement in early clinical trials: results from the European EUFEMED survey
2025 · J. Klein, T. van Iersel, et al. · Frontiers in Pharmacology · 4
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THU0150 Safety, Pharmacokinetics, Pharmacodynamics, and Food Effect of an Oral Bruton's Tyrosine Kinase Inhibitor HM71224 in Healthy Subjects
2014 · Y.-K. Yoon, S. Hadi, et al. · Annals of the Rheumatic Diseases · 4
Single intravenous high-dose sugammadex (up to 96 mg/kg) is generally safe and well tolerated in healthy volunteers
2008 · P. Peeters, P. Passier, et al. · European Journal of Anaesthesiology · 4
Why do healthy volunteers participate in clinical trials?
2026 · Thijs van Iersel, Jelle Klein, et al. · British Journal of Clinical Pharmacology · 2
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P.3.a.026 Safety, tolerability and D2 occupancy of the fast dissociating D2 antagonist JNJ-37822681 in healthy subjects
2010 · M. Schmidt, P. de Boer, et al. · European Neuropsychopharmacology · 2
Erratum for Kersemaekers et al., Pharmacokinetics and Safety Study of Posaconazole Intravenous Solution Administered Peripherally to Healthy Subjects
2016 · Wendy M. Kersemaekers, Thijs van Iersel, et al. · Antimicrobial Agents and Chemotherapy · 1
The Role of Contract Research Organizations (CROs) in Imaging for the Drug Development Process
2012 · Izaak den Daas, Thijs van Iersel, et al. · WORLD SCIENTIFIC eBooks · 1
P.1.e.024 D2 receptor occupancy with HC-raclopride PET following single and multiple dose: does steady state make a difference?
2009 · M. Schmidt, E. Mannaert, et al. · European Neuropsychopharmacology · 1
Collecting Metabolite Pharmacokinetics in Drug–Drug Interaction Studies: A Review of Industry Practices and Data Utilization
2026 · Tatyana Dubich, Thijs van Iersel, et al. · Clinical Pharmacokinetics
Bioequivalence Between a Gantenerumab Disposable Syringe and an Autoinjector: A Randomized Controlled Trial in Healthy Volunteers
2026 · Dietmar Schwab, Carsten Hofmann, et al. · Clinical Pharmacology in Drug Development
Matching in Organ Impairment Studies: A Systematic Review of Accepted Methodologies
2025 · Tatyana Dubich, Gerhard Arold, et al. · The AAPS Journal
Works count: 29
Citation count: 959
H-index: 11
I10-index: 11
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