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Alexander J. Clarke

Observed names: A J Clarke, Alex Clarke, Alexander Clarke, Alexander J Clarke, Clarke, Alexander
Observed institutions: King's College London, Hammersmith Hospital, University of Oxford, MRC Human Immunology Unit, National Hospital for Neurology and Neurosurgery, Kennedy Institute of Rheumatology, Imperial College London, Medical Research Council
ORCID: 0000-0003-2846-7860
Observed ORCID: 0000-0003-2846-7860
OpenAlex ID: A5028030494
Autophagy in the renewal, differentiation and homeostasis of immune cells
2018 · Alexander J. Clarke, Anna Katharina Simon · Nature reviews. Immunology · 357
Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation
2017 · Thomas Riffelmacher, Alexander Clarke, et al. · Immunity · 298
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Autophagy is activated in systemic lupus erythematosus and required for plasmablast development
2014 · Alexander J Clarke, Ursula Ellinghaus, et al. · Annals of the Rheumatic Diseases · 252
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B1a B cells require autophagy for metabolic homeostasis and self-renewal
2018 · Alexander J. Clarke, Thomas Riffelmacher, et al. · The Journal of Experimental Medicine · 148
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Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus
2019 · Christopher A. Odhams, Amy L. Roberts, et al. · Nature Communications · 122
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B Cell Metabolism and Autophagy in Autoimmunity
2021 · Iwan G. A. Raza, Alexander J. Clarke · Frontiers in Immunology · 105
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Plasma iron controls neutrophil production and function
2022 · Joe N. Frost, Sarah K. Wideman, et al. · Science Advances · 86
EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
2021 · Suyasha Roy, Zaigham Abbas Rizvi, et al. · Nature Communications · 69
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Dynamic mitochondrial transcription and translation in B cells control germinal center entry and lymphomagenesis
2023 · Yavuz F. Yazicioglu, Eros Marin, et al. · Nature Immunology · 66
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Amplification of autoimmune organ damage by NKp46-activated ILC1s
2024 · Stylianos-Iason Biniaris-Georgallis, Tom Aschman, et al. · Nature · 34
Genetics of rheumatic disease
2009 · Alex Clarke, Timothy J Vyse · Arthritis Research & Therapy · 29
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Systematic Review: Monoclonal Antibody-Induced Subacute Cutaneous Lupus Erythematosus
2020 · Chrissy Bolton, Yifan Chen, et al. · Drugs in R&D · 28
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Fuelling B cells: dynamic regulation of B cell metabolism
2024 · Julia C. Johnstone, Yavuz F. Yazicioglu, et al. · Current Opinion in Immunology · 27
A cellular overview of immunometabolism in systemic lupus erythematosus
2023 · Antonios Psarras, Alexander Clarke · Oxford Open Immunology · 27
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Asparagine availability controls germinal center B cell homeostasis
2024 · Yavuz F. Yazicioglu, Eros Marin, et al. · Science Immunology · 20
LAT1 enables T cell activation under inflammatory conditions
2023 · Joy Ogbechi, Helen L. Wright, et al. · Journal of Autoimmunity · 17
The unusual metabolism of germinal center B cells
2025 · Caitlin J. Gracie, Robert Mitchell, et al. · Trends in Immunology · 15
Mitochondrial control of lymphocyte homeostasis
2024 · Yavuz F. Yazicioglu, Robert J. Mitchell, et al. · Seminars in Cell and Developmental Biology · 11
ALK positive inflammatory myofibroblastic tumour of the pineal region
2005 · A J Clarke, T S Jacques, et al. · Journal of Clinical Pathology · 9
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One carbon (metabolism) to rule T cell identity
2021 · Felix Clemens Richter, Alexander J. Clarke · Nature reviews. Immunology · 6
Non-canonical autophagy LAPs lupus
2016 · A K Simon, A J Clarke · Cell Death and Differentiation · 6
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A cross-sectional audit of the uptake of seasonal and H1N1 influenza vaccination amongst patients with rheumatoid arthritis in a London hospital.
2011 · A J Clarke, P Gulati, et al. · PubMed · 3
The autoantigen TRIM21 assembles proinflammatory immune complexes after lytic cell death
2026 · Esther L. Jones Evans, Benjamin Demarco, et al. · Science Immunology · 2
The adaptor protein TASL is required for age-related B cell emergence and lupus-like disease development in mice
2026 · Julia C. Johnstone, Robert Mitchell, et al. · PLoS Biology · 2
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Glycogen synthase kinase-3 is essential for Treg development and function
2025 · Matheswaran Kandasamy, Hana F. Andrew, et al. · Cell Reports · 2
Works count: 39
Citation count: 1,745
H-index: 16
I10-index: 18
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