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Gessica Filocamo
Observed name:
G Filocamo
Observed institutions:
Merck & Co., Inc., Rahway, NJ, USA (United States),
Institute of Molecular Biology and Pathology,
Sapienza University of Rome
OpenAlex ID:
A5028641408
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus
2002
·
Elisa Scarselli
, Helenia Ansuini
, et al.
·
The EMBO Journal
·
1,236
Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor
2004
·
Alessandro Vannini
, Cinzia Volpari
, et al.
·
Proceedings of the National Academy of Sciences
·
647
Dissecting the Biological Functions of Drosophila Histone Deacetylases by RNA Interference and Transcriptional Profiling
2006
·
Cristiana Foglietti
, Gessica Filocamo
, et al.
·
Journal of Biological Chemistry
·
92
PDF
Loss of Histone Deacetylase 4 Causes Segregation Defects during Mitosis of p53-Deficient Human Tumor Cells
2009
·
Bruno Cadot
, Mirko Brunetti
, et al.
·
Cancer Research
·
42
PDF
Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclo- propyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydro-imidazo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, Part 2
2011
·
Olaf Kinzel
, Anna Alfieri
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
37
Interplay of the E Box, the Cyclic AMP Response Element, and HTF4/HEB in Transcriptional Regulation of the Neurospecific, Neurotrophin-Inducible vgf Gene†
1997
·
Giuliana Di Rocco
, Maria Pennuto
, et al.
·
Molecular and Cellular Biology
·
33
Identification of MK-5710 ((8aS)-8a-methyl-1,3-dioxo-2-[(1S,2R)-2-phenylcyclopropyl]-N-(1-phenyl-1H-pyrazol-5-yl)hexahydroimid azo[1,5-a]pyrazine-7(1H)-carboxamide), a potent smoothened antagonist for use in Hedgehog pathway dependent malignancies, Part 1
2011
·
Savina Malancona
, Sergio Altamura
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
30
Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells
2013
·
Raffaella Spina
, Gessica Filocamo
, et al.
·
Oncotarget
·
29
PDF
Chimeric Sindbis viruses dependent on the NS3 protease of hepatitis C virus
1997
·
G Filocamo
, L Pacini
, et al.
·
Journal of Virology
·
26
MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma
2016
·
Gessica Filocamo
, Mirko Brunetti
, et al.
·
Molecular Cancer Therapeutics
·
23
PDF
Nonrheumatoid IgM in human hepatitis C virus-associated type II cryoglobulinemia recognize mimotopes of the CD4-like LAG-3 protein
1996
·
M Mecchia
, M Casato
, et al.
·
The Journal of Immunology
·
20
In Vivo Selection of Protease Cleavage Sites by Using Chimeric Sindbis Virus Libraries
2000
·
Laura Pacini
, Alessandra Vitelli
, et al.
·
Journal of Virology
·
14
Selection of Functional Variants of the NS3-NS4A Protease of Hepatitis C Virus by Using Chimeric Sindbis Viruses
1999
·
Gessica Filocamo
, Laura Pacini
, et al.
·
Journal of Virology
·
14
PDF
Efficacy of selective histone deacetylase 6 inhibition in mouse models of Pseudomonas aeruginosa infection: A new glimpse for reducing inflammation and infection in cystic fibrosis
2022
·
Margherita Brindisi
, Simona Barone
, et al.
·
European Journal of Pharmacology
·
12
Smoothened antagonists: a promising new class of antitumor agents
2009
·
Paola Gallinari
, Gessica Filocamo
, et al.
·
Expert Opinion on Drug Discovery
·
12
Challenging triple negative breast cancer through HDAC6 selective inhibition: Novel cap-group identification, structure-activity relationships, computational and biological studies
2025
·
Simona Barone
, Ivana Bello
, et al.
·
European Journal of Medicinal Chemistry
·
8
Fine-tuning the combination of novel spirocyclic capping moieties and heterocyclic zinc binding groups for selective HDAC6 inhibition: design, synthesis, kinetic and biological studies
2026
·
Simona Barone
, Ivana Bello
, et al.
·
European Journal of Medicinal Chemistry
·
2
Abstract 5045: Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells.
2013
·
Raffaella Spina
, Gessica Filocamo
, et al.
·
Cancer Research
·
2
Structure-Based Design of HDAC6 Inhibitors Targeting the L2 Pocket: Modulating Autophagy and Liquid−Liquid Phase Separation in Lung Cancer
2026
·
Simona Barone
, Abraham Eafa
, et al.
·
Journal of Medicinal Chemistry
·
1
PDF
Trifunctional Pyrrolidine-Carbamate Self-Immolative Spacers Decouple Enzymatic Activation from Drug Release in Antibody−Drug Conjugates
2026
·
Mattia Failla
, Elia Ubiali
, et al.
·
Bioconjugate Chemistry
PDF
Abstract A006: Identification of a novel, safety-engineered ADC directed against FGFR4 for the treatment of Rhabdomyosarcoma
2026
·
Christian Steinkühler
, Mirko Brunetti
, et al.
·
Cancer Research
Targeting Colorectal Cancer Stem Cells Through Inhibition of the Fibroblast Growth Factor Receptor 4 Pathway with a Novel Antibody
2026
·
Gessica Filocamo
, Mariachiara Buccarelli
, et al.
·
Cancers
PDF
Supplementary Figure S1 from MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma
2023
·
Gessica Filocamo
, Mirko Brunetti
, et al.
Supplementary Table S1 from MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma
2023
·
Gessica Filocamo
, Mirko Brunetti
, et al.
Supplementary Table S2 from MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma
2023
·
Gessica Filocamo
, Mirko Brunetti
, et al.
PDF
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Works count:
38
Citation count:
2,280
H-index:
13
I10-index:
15
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