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Inge Verbrugge
Observed names:
I Verbrugge,
I. Verbrugge,
Verbrugge, Inge
Institution:
Genmab (Netherlands)
Observed institutions:
Janssen (Belgium),
The University of Melbourne,
Pfizer (United States),
Peter MacCallum Cancer Centre,
The Netherlands Cancer Institute,
University Medical Center Utrecht,
Juntendo University,
Genmab (Netherlands),
Oncode Institute
show all 9
ORCID:
0000-0003-4298-061X
Observed ORCID:
0000-0003-4298-061X
OpenAlex ID:
A5028764975
Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies
2012
·
Inge Verbrugge
, Jim Hagekyriakou
, et al.
·
Cancer Research
·
275
Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma
2016
·
Marcel A. Deken
, Jules Gadiot
, et al.
·
OncoImmunology
·
153
PDF
Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy
2016
·
Maarten Swart
, Inge Verbrugge
, et al.
·
Frontiers in Oncology
·
139
PDF
Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors
2014
·
Michael Bots
, Inge Verbrugge
, et al.
·
Blood
·
133
The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia
2015
·
Adele Baker
, Gareth P. Gregory
, et al.
·
Cancer Research
·
117
SnapShot: Extrinsic Apoptosis Pathways
2010
·
Inge Verbrugge
, Ricky W. Johnstone
, et al.
·
Cell
·
95
PDF
Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population
2017
·
Nadine Hein
, Donald P. Cameron
, et al.
·
Blood
·
92
PDF
Ubiquitination by the Membrane-associated RING-CH-8 (MARCH-8) Ligase Controls Steady-state Cell Surface Expression of Tumor Necrosis Factor-related Apoptosis Inducing Ligand (TRAIL) Receptor 1*
2013
·
Bert van de Kooij
, Inge Verbrugge
, et al.
·
Journal of Biological Chemistry
·
82
PDF
Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells
2021
·
Elisa Matas-Rico
, Elselien Frijlink
, et al.
·
Cell Reports
·
80
PDF
Radiotherapy and Cisplatin Increase Immunotherapy Efficacy by Enabling Local and Systemic Intratumoral T-cell Activity
2019
·
Paula Kroon
, Elselien Frijlink
, et al.
·
Cancer Immunology Research
·
47
PDF
Smac/DIABLO release from mitochondria and XIAP inhibition are essential to limit clonogenicity of Type I tumor cells after TRAIL receptor stimulation
2010
·
C Maas
, I Verbrugge
, et al.
·
Cell Death and Differentiation
·
44
Ionizing radiation modulates the TRAIL death-inducing signaling complex, allowing bypass of the mitochondrial apoptosis pathway
2007
·
I Verbrugge
, E de Vries
, et al.
·
Oncogene
·
44
PD-1 or CTLA-4 blockade promotes CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice
2024
·
Elselien Frijlink
, Douwe M.T. Bosma
, et al.
·
Journal of Clinical Investigation
·
37
PDF
TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy
2006
·
Esther H.J. Wissink
, Inge Verbrugge
, et al.
·
Radiotherapy and Oncology
·
35
Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma
2016
·
Paula Kroon
, Jules Gadiot
, et al.
·
Cancer Immunology Immunotherapy
·
34
PDF
The Curative Outcome of Radioimmunotherapy in a Mouse Breast Cancer Model Relies on mTOR Signaling
2014
·
Inge Verbrugge
, Alessia Gasparini
, et al.
·
Radiation Research
·
32
Combining Radiotherapy with APO010 in Cancer Treatment
2009
·
Inge Verbrugge
, Esther H.J. Wissink
, et al.
·
Clinical Cancer Research
·
29
Radiation and anticancer drugs can facilitate mitochondrial bypass by CD95/Fas via c-FLIP downregulation
2009
·
I Verbrugge
, C Maas
, et al.
·
Cell Death and Differentiation
·
24
Promises and challenges of anticancer drugs that target the epigenome
2011
·
Inge Verbrugge
, Ricky W Johnstone
, et al.
·
Epigenomics
·
22
Stem cell-derived cardiomyocytes after bone marrow and heart transplantation
2007
·
R A de Weger
, I Verbrugge
, et al.
·
Bone Marrow Transplantation
·
16
Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies
2012
·
Inge Verbrugge
, Mara Galli
, et al.
·
OncoImmunology
·
14
PDF
Regulating the TRAIL of Destruction: How A20 Protects Glioblastomas from TRAIL-Mediated Death
2012
·
Inge Verbrugge
, Ricky W. Johnstone
·
Cancer Discovery
·
12
Enhancing radiation response by a second-generation TRAIL receptor agonist using a new in vitro organoid model system
2020
·
Shuraila F. Zerp
, Zainab Bibi
, et al.
·
Clinical and Translational Radiation Oncology
·
8
PDF
Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8 + T cells
2020
·
Elisa Matas-Rico
, Elselien Frijlink
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
6
PDF
The IL-6 hypothesis in COVID-19: A phase 2, randomised, double-blind, placebo-controlled study to evaluate the efficacy and safety of free IL-6 sequestration by the monoclonal antibody sirukumab in severe and critical COVID-19
2024
·
Robert L. Gottlieb
, Meredith Clement
, et al.
·
Journal of Infection
·
5
PDF
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Works count:
82
Citation count:
1,593
H-index:
19
I10-index:
22
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