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Hao Ruan

First orally bioavailable prodrug of proteolysis targeting chimera (PROTAC) degrades cyclin-dependent kinases 2/4/6 in vivo
2020 · Mingming Wei, Rui Zhao, et al. · European Journal of Medicinal Chemistry · 109
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis
2021 · Hai-long Li, Yi-ying Wei, et al. · Acta Pharmacologica Sinica · 74
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Anlotinib attenuated bleomycin-induced pulmonary fibrosis via the TGF-β1 signalling pathway
2019 · Hao Ruan, Ziwei Lv, et al. · Journal of Pharmacy and Pharmacology · 62
Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach
2018 · Bart Hens, Marival Bermejo, et al. · European Journal of Pharmaceutical Sciences · 57
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Effect of dihydromyricetin on SARS-CoV-2 viral replication and pulmonary inflammation and fibrosis
2021 · Ting Xiao, Yuli Wei, et al. · Phytomedicine · 56
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Fedratinib Attenuates Bleomycin-Induced Pulmonary Fibrosis via the JAK2/STAT3 and TGF-β1 Signaling Pathway
2021 · Hao Ruan, Jiaoyan Luan, et al. · Molecules · 42
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Bergenin attenuates bleomycin‐induced pulmonary fibrosis in mice via inhibiting TGF ‐β1 signaling pathway
2021 · Xiaohe Li, Yanhua Wang, et al. · Phytotherapy Research · 33
Lenalidomide attenuates post-inflammation pulmonary fibrosis through blocking NF-κB signaling pathway
2021 · Xiaohe Li, Qing Liang, et al. · International Immunopharmacology · 25
Ellagic Acid Attenuates BLM-Induced Pulmonary Fibrosis via Inhibiting Wnt Signaling Pathway
2021 · Xiaohe Li, Kai Huang, et al. · Frontiers in Pharmacology · 25
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Clevudine attenuates bleomycin-induced early pulmonary fibrosis via regulating M2 macrophage polarization
2021 · Shuangling Li, Shaoyan Gao, et al. · International Immunopharmacology · 23
Deglycosylated Azithromycin Targets Transgelin to Enhance Intestinal Smooth Muscle Function
2020 · Weilong Zhong, Bo Sun, et al. · iScience · 19
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Deglycosylated Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1 Signaling Pathway
2021 · Hao Ruan, Shaoyan Gao, et al. · Molecules · 12
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Microbiota regulation in constipation and colorectal cancer
2023 · Li-Wei Wang, Hao Ruan, et al. · World Journal of Gastrointestinal Oncology · 11
Discovery and Optimization of a Novel 2H-Pyrazolo[3,4-d]pyrimidine Derivative as a Potent Irreversible Pan-Fibroblast Growth Factor Receptor Inhibitor
2021 · Yujiao Wei, Yanting Tang, et al. · Journal of Medicinal Chemistry · 10
Pazopanib attenuated bleomycin-induced pulmonary fibrosis via suppressing TGF-β1 signaling pathway
2024 · Kai Huang, Qianyi Zhang, et al. · Journal of Thoracic Disease · 2
Design, synthesis, biological evaluation, and molecular docking studies of aniline-pyrimidine derivatives as potential anti-non-small cell lung cancer agents
2026 · Wenjun Liang, Hao Ruan, et al. · Results in Chemistry · 1
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Roseburia intestinalis-derived inosine improves intestinal motility by activating TGF-β1/p-Smad3/Transgelin signaling axis
2025 · Xiaoqian Dong, Hao Zhang, et al. · Journal of Translational Medicine · 1
Research Progress of Idiopathic Pulmonary Fibrosis Complicated with Lung Cancer
2024 · Hao Ruan, Zihui Zhang, et al. · International Journal of Cancer Management
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Potential pharmacological mechanism of Colitis treatment by diosmetin
2020 · hailong Li, Yiying Wei, et al.
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Works count: 19
Citation count: 562
H-index: 12
I10-index: 14
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