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Author

Haruaki Kurasaki

Institution: Peptidream (Japan)
ORCID: 0000-0003-4276-0545
Observed ORCID: 0000-0003-4276-0545
OpenAlex ID: A5029399800
Total Synthesis of Grandisine D
2009 · Haruaki Kurasaki, Iwao Okamoto, et al. · Organic Letters · 43
Sulfonamide-based non-alkyne LpxC inhibitors as Gram-negative antibacterial agents
2016 · Tetsuya Kawai, Iwase Kazuhiko, et al. · Bioorganic & Medicinal Chemistry Letters · 36
LpxC Inhibitors: Design, Synthesis, and Biological Evaluation of Oxazolidinones as Gram-negative Antibacterial Agents
2016 · Haruaki Kurasaki, Kosuke Tsuda, et al. · ACS Medicinal Chemistry Letters · 36
A Flexible Approach to Grandisine Alkaloids: Total Synthesis of Grandisines B, D, and F
2009 · Haruaki Kurasaki, Iwao Okamoto, et al. · Chemistry - A European Journal · 33
Synthesis and in vitro antitumor activity of novel 2-alkyl-5-methoxycarbonyl-11-methyl-6H-pyrido[4,3-b]carbazol-2-ium and 2-alkylellipticin-2-ium chloride derivatives
2014 · Ryota Mori, Asako Kato, et al. · European Journal of Medicinal Chemistry · 23
Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5)
2015 · Sheo B. Singh, David E. Kaelin, et al. · Bioorganic & Medicinal Chemistry Letters · 19
Isostearyl Mixed Anhydrides for the Preparation ofN-Methylated Peptides UsingC-Terminally UnprotectedN-Methylamino Acids
2020 · Haruaki Kurasaki, Akihiro Nagaya, et al. · Organic Letters · 18
Structure activity relationship of substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-4)
2015 · Sheo B. Singh, David E. Kaelin, et al. · Bioorganic & Medicinal Chemistry Letters · 17
ODP353 Sustained Suppression of IGF1 with AZP-3813, a Bicyclic 16-Amino Acid Peptide Antagonist of the Human Growth Hormone Receptor and a Potential New Treatment for Acromegaly
2022 · Michael Culler, Stephane Milano, et al. · Journal of the Endocrine Society · 9
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Extended Solution-phase Peptide Synthesis Strategy Using Isostearyl-Mixed Anhydride Coupling and a New C-Terminal Silyl Ester-Protecting Group for N-Methylated Cyclic Peptide Production
2021 · Akihiro Nagaya, Shota Murase, et al. · Organic Process Research & Development · 9
Synthesis and evaluation of opioid receptor-binding affinity of elaeocarpenine and its analogs
2010 · Haruaki Kurasaki, Iwao Okamoto, et al. · Bioorganic & Medicinal Chemistry Letters · 8
Determination of binding modes and binding constants for the complexes of 6H-pyrido[4,3-b]carbazole derivatives with DNA
2016 · Akihito Shimazu, Masashi Kawagoshi, et al. · Bioorganic & Medicinal Chemistry · 7
Additive effects of ALXN2420, a GH receptor antagonist, and octreotide on IGF1 suppression in vivo
2025 · Guillaume Ravel, Xavier Gaume, et al. · European Journal of Endocrinology · 6
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THU046 Repeated Treatment With AZP-3813, A Bicyclic, 16-Amino Acid Peptide Antagonist Of The Human Growth Hormone Receptor, Induces Enhanced Suppression Of IGF1 In Beagle Dogs
2023 · Guillaume Ravel, Clémentine Chalmey, et al. · Journal of the Endocrine Society · 4
AZP-3813, a bicyclic 16-amino acid peptide antagonist of the human growth hormone receptor as a potential new treatment for acromegaly
2022 · Stephane Milano, Haruaki Kurasaki, et al. · Endocrine Abstracts · 4
Enantioselective Ring Opening of Meso-Epoxide —Scope of Halohydrination—
2009 · Haruaki Kurasaki · Journal of Synthetic Organic Chemistry Japan · 4
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Additive effect of combined treatment with the small peptide GH receptor antagonist, AZP-3813, and the somatostatin analog, octreotide, in decreasing IGF1 levels in the rat
2024 · Guillaume Ravel, Corentin Berardet, et al. · Endocrine Abstracts · 1
2524. Safety and Pharmacokinetics of PA-001, a New Potential COVID-19 Drug That Targets the S2 Subunit of SARS-CoV-2 Spike Protein, in Healthy Subjects
2023 · Haruaki Kurasaki, Masaki Ohuchi, et al. · Open Forum Infectious Diseases · 1
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2141. Preclinical Evaluation of PA-001: A Novel, Potential Macrocyclic Peptide-Based Treatment for COVID-19 Which Binds to the S2 Subunit of SARS-CoV-2 Spike Protein
2023 · Tatsuro Kawamura, Masaki Ohuchi, et al. · Open Forum Infectious Diseases · 1
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A macrocyclic peptide-based fusion inhibitor targeting SARS-CoV-2 Spike S2 subunit
2026 · Hirofumi Ohashi, Tatsuro Kawamura, et al. · bioRxiv (Cold Spring Harbor Laboratory)
7145 Enhanced Ability of the Small Peptide GH Receptor Antagonist, AZP-3813, to Decrease IGF1 When Combined with the Somatostatin Analog, Octreotide
2024 · Guillaume Ravel, Corentin Berardet, et al. · Journal of the Endocrine Society
Exploring Innovative Liquid-Phase Peptide Synthesis Strategies with Silane-Containing Molecules
2024 · Naoki Nishizawa, Akihiro Nagaya, et al. · European Peptide Symposium (EPS)
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AZP-3813, a bicyclic, 16-amino acid peptide antagonist of the human growth hormone receptor, effectively suppresses IGF1 in beagle dogs
2023 · Guillaume Ravel, Clementine Chalmey, et al. · Endocrine Abstracts
DNAと6H‐ピリド[4,3‐b]カルバゾール誘導体との複合体の結合様式および結合定数の決定
2017 · Shimazu Akihito, Masashi Kawagoshi, et al. · Bioorganic & Medicinal Chemistry
ChemInform Abstract: Total Synthesis of Grandisine D (I).
2009 · Haruaki Kurasaki, Iwao Okamoto, et al. · ChemInform
Works count: 25
Citation count: 279
H-index: 9
I10-index: 8
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