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Anders Wittrup

Observed names: A WITTRUP, Wittrup, Anders
ORCID: 0000-0003-4918-0500
Observed ORCID: 0000-0003-4918-0500
OpenAlex ID: A5029459882
Knocking down disease: a progress report on siRNA therapeutics
2015 · Anders Wittrup, Judy Lieberman · Nature Reviews Genetics · 830
Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1
2013 · Katrin J. Svensson, Helena C. Christianson, et al. · Journal of Biological Chemistry · 721
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Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
2015 · Anders Wittrup, Angela Ai, et al. · Nature Biotechnology · 715
The Human Antimicrobial Peptide LL-37 Transfers Extracellular DNA Plasmid to the Nuclear Compartment of Mammalian Cells via Lipid Rafts and Proteoglycan-dependent Endocytosis
2004 · Staffan Sandgren, Anders Wittrup, et al. · Journal of Biological Chemistry · 247
Nuclear delivery of macromolecules: barriers and carriers
2004 · M BELTING, S SANDGREN, et al. · Advanced Drug Delivery Reviews · 211
Imaging small molecule-induced endosomal escape of siRNA
2020 · Hampus Du Rietz, Hampus Hedlund, et al. · Nature Communications · 210
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Nanotubes, exosomes, and nucleic acid–binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease
2008 · Mattias Belting, Anders Wittrup · The Journal of Cell Biology · 163
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Cellular and biophysical barriers to lipid nanoparticle mediated delivery of RNA to the cytosol
2025 · Johanna M. Johansson, Hampus Du Rietz, et al. · Nature Communications · 134
N-terminal peptides from unprocessed prion proteins enter cells by macropinocytosis
2006 · Mazin Magzoub, Staffan Sandgren, et al. · Biochemical and Biophysical Research Communications · 105
Gene Knockdown by EpCAM Aptamer–siRNA Chimeras Suppresses Epithelial Breast Cancers and Their Tumor-Initiating Cells
2015 · Adi Gilboa-Geffen, Peter Hamar, et al. · Molecular Cancer Therapeutics · 91
Cancer Cells Can Exhibit a Sparing FLASH Effect at Low Doses Under Normoxic In Vitro-Conditions
2021 · Gabriel Adrian, Elise Konradsson, et al. · Frontiers in Oncology · 79
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Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery
2010 · Anders Wittrup, Si-He Zhang, et al. · Proceedings of the National Academy of Sciences · 74
ScFv Antibody-induced Translocation of Cell-surface Heparan Sulfate Proteoglycan to Endocytic Vesicles
2009 · Anders Wittrup, Si-He Zhang, et al. · Journal of Biological Chemistry · 61
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Identification of Proteins Released by Mammalian Cells That Mediate DNA Internalization through Proteoglycan-dependent Macropinocytosis
2007 · Anders Wittrup, Staffan Sandgren, et al. · Journal of Biological Chemistry · 44
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Single-cell quantification and dose-response of cytosolic siRNA delivery
2023 · Hampus Hedlund, Hampus Du Rietz, et al. · Nature Communications · 43
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Auto-segmentations by convolutional neural network in cervical and anorectal cancer with clinical structure sets as the ground truth
2020 · Hanna Sartor, David Minarik, et al. · Clinical and Translational Radiation Oncology · 34
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Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation
2008 · Mattias Belting, Toin Van Kuppevelt, et al. · International Journal of Oncology · 28
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Macromolecular Drug Delivery: Basic Principles and Therapeutic Applications
2009 · Mattias Belting, Anders Wittrup · Molecular Biotechnology · 24
Developments in Macromolecular Drug Delivery
2008 · Mattias Belting, Anders Wittrup · Methods in molecular biology · 18
Studies of Proteoglycan Involvement in CPP-Mediated Delivery
2010 · Anders Wittrup, Si-He Zhang, et al. · Methods in molecular biology · 12
Characterizing Peptide-Mediated DNA Internalization in Human Cancer Cells
2008 · Anders Wittrup, Mattias Belting · Methods in molecular biology · 8
Abstract LB-299: Gene knockdown by EpCAM aptamer-siRNA chimeras suppresses epithelial breast cancers and their tumor-initiating cells
2015 · Adi Gilboa-Geffen, Peter Hamar, et al. · Cancer Research · 7
Proteoglycans as Endocytosis Receptors for CPPs
2006 · Mattias Belting, Anders Wittrup, et al. · Pharmacology & toxicology · 1
Source data file_JohanssonJM_NAR
2026 · Johansson, Johanna M, Du Rietz, Hampus, et al. · Zenodo (CERN European Organization for Nuclear Research)
Nutritional Access Modulates Activity of a Small Molecule Enhancer of Endosomal Escape
2026 · Sten Wilhelmson-Andén, Hampus Du Rietz, et al. · bioRxiv (Cold Spring Harbor Laboratory)
Works count: 31
Citation count: 3,860
H-index: 18
I10-index: 20
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