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Lingtian Zhang

Observed name: Ling-Tian Zhang
ORCID: 0000-0003-3898-3287
Observed ORCID: 0000-0003-3898-3287
OpenAlex ID: A5029467958
Discovery of SP-96, the first non-ATP-competitive Aurora Kinase B inhibitor, for reduced myelosuppression
2020 · Naga Rajiv Lakkaniga, Lingtian Zhang, et al. · European Journal of Medicinal Chemistry · 42
Catalyst free, C-3 functionalization of imidazo[1,2- a ]pyridines to rapidly access new chemical space for drug discovery efforts
2018 · Naresh Gunaganti, Anupreet Kharbanda, et al. · Chemical Communications · 38
Screening the key genes of hair follicle growth cycle in Inner Mongolian Cashmere goat based on RNA sequencing
2020 · Rui Su, Gao Gong, et al. · Archives animal breeding/Archiv für Tierzucht · 37
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Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation
2021 · Wei Yan, Lingtian Zhang, et al. · European Journal of Medicinal Chemistry · 35
Pyrrolo[2,3-d]pyrimidine derivatives as inhibitors of RET: Design, synthesis and biological evaluation
2020 · Naga Rajiv Lakkaniga, Naresh Gunaganti, et al. · European Journal of Medicinal Chemistry · 35
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Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology
2020 · Marialuisa Moccia, Brendan Frett, et al. · Journal of Medicinal Chemistry · 34
Sulfation of afimoxifene, endoxifen, raloxifene, and fulvestrant by the human cytosolic sulfotransferases (SULTs): A systematic analysis
2015 · Ying Hui, Lijun Luo, et al. · Journal of Pharmacological Sciences · 28
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Discovery of imidazo[1,2-a]pyridine-thiophene derivatives as FLT3 and FLT3 mutants inhibitors for acute myeloid leukemia through structure-based optimization of an NEK2 inhibitor
2021 · Lingtian Zhang, Naga Rajiv Lakkaniga, et al. · European Journal of Medicinal Chemistry · 27
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose
2022 · Lingtian Zhang, Marialuisa Moccia, et al. · Journal of Medicinal Chemistry · 22
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Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases
2021 · Marialuisa Moccia, Donglin Yang, et al. · Scientific Reports · 20
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Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT
2018 · Jaideep B. Bharate, Nicholas McConnell, et al. · Scientific Reports · 20
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Discovery of Fused Benzimidazole-Imidazole Autophagic Flux Inhibitors for Treatment of Triple-Negative Breast Cancer
2022 · Dong-Lin Yang, Ya-Jun Zhang, et al. · European Journal of Medicinal Chemistry · 17
Intramolecular cyclization of imidazo[1,2- a ]pyridines via a silver mediated/palladium catalyzed C–H activation strategy
2019 · Debasmita Saha, Anupreet Kharbanda, et al. · Organic Chemistry Frontiers · 16
Progress in Research and Prospects for Application of Precision Gene-Editing Technology Based on CRISPR–Cas9 in the Genetic Improvement of Sheep and Goats
2024 · Zeyu Lu, Lingtian Zhang, et al. · Agriculture · 13
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Sulfation of benzyl alcohol by the human cytosolic sulfotransferases (SULTs): a systematic analysis
2015 · Lingtian Zhang, Katsuhisa Kurogi, et al. · Journal of Applied Toxicology · 8
Discovery of 4-aminoquinolines as highly selective TGFβR1 inhibitors with an attenuated MAP4K4 profile for potential applications in immuno-oncology
2021 · Anupreet Kharbanda, Phuc Tran, et al. · European Journal of Medicinal Chemistry · 4
Discovery and biological evaluation of phthalazines as novel non-kinase TGFβ pathway inhibitors
2021 · Anupreet Kharbanda, Lingtian Zhang, et al. · European Journal of Medicinal Chemistry · 4
[Progress in goat genome studies].
2019 · Feng-Hong Wang, Lei Zhang, et al. · PubMed · 4
Strategic Use of Benzylic Alcohols Reveals Cryptic Hydrogen-Bonding Interactions: Discovery of HBC-12551 as a Potent Noncovalent Bruton’s Tyrosine Kinase Inhibitor
2026 · Gang Liu, Shuaishuai Liu, et al. · Journal of Medicinal Chemistry · 2
Estimation of genetic parameters for horn traits and essential economic traits in Inner Mongolia Cashmere goats
2021 · Lei Zhang, Fenghong Wang, et al. · Czech Journal of Animal Science · 2
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Abstract B020: Preclinical assessment of WRN inhibitor HS-10515 for selective targeting of MSI-H cancers
2025 · Tzu-Pei Chang, Gang Liu, et al. · Molecular Cancer Therapeutics
Works count: 21
Citation count: 408
H-index: 13
I10-index: 14
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