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Ana Tapia‐Abellán

Observed names: A Tapia-Abellán, A. Tapia-Abellan, Ana Tapia, Ana Tapia Abellán, Ana Tapia-Abellán, Ana Tapía-Abellán, Tapia Abellán, Ana, Tapia-Abellan, Ana, Tapia-Abellán, Ana
Observed institutions: Santa Lucía University General Hospital, Instituto Murciano de Investigación Biosanitaria, Hospital Universitario Virgen de la Arrixaca, Universidad de Murcia, University of Tübingen, UCLouvain
ORCID: 0000-0002-6235-4248
Observed ORCID: 0000-0002-6235-4248
OpenAlex ID: A5029577701
MCC950 closes the active conformation of NLRP3 to an inactive state
2019 · Ana Tapia-Abellán, Diego Angosto-Bazarra, et al. · Nature Chemical Biology · 456
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
2017 · Mattia Cocco, Carolina Pellegrini, et al. · Journal of Medicinal Chemistry · 176
Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation
2021 · Ana Tapia-Abellán, Diego Angosto-Bazarra, et al. · Science Advances · 156
NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
2018 · Iva Hafner-Bratkovič, Petra Sušjan, et al. · Nature Communications · 149
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BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
2021 · Zsófia Agnes Bittner, Xiao Liu, et al. · The Journal of Experimental Medicine · 86
Recent insights into the regulatory networks of NLRP3 inflammasome activation
2020 · Alexander N. R. Weber, Zsófia A. Bittner, et al. · Journal of Cell Science · 85
Unleashing the power of CAR-M therapy in solid tumors: a comprehensive review
2025 · Ahsen Morva, Ana Belén Arroyo, et al. · Frontiers in Immunology · 52
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Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production
2024 · Cristina Molina-López, Laura Hurtado-Navarro, et al. · Nature Communications · 41
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The peritoneal macrophage inflammatory profile in cirrhosis depends on the alcoholic or hepatitis C viral etiology and is related to ERK phosphorylation
2012 · Ana Tapia-Abellán, María Martínez-Esparza, et al. · BMC Immunology · 32
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Role of MAP Kinases and PI 3K‐Akt on the cytokine inflammatory profile of peritoneal macrophages from the ascites of cirrhotic patients
2012 · Ana Tapia‐Abellán, Antonio J. Ruiz‐Alcaraz, et al. · Liver International · 31
Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization
2019 · Alberto Baroja-Mazo, Vincent Compan, et al. · Scientific Reports · 30
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Peritoneal macrophage priming in cirrhosis is related to ERK phosphorylation and IL‐6 secretion
2010 · Antonio J. Ruiz‐Alcaraz, María Martínez‐Esparza, et al. · European Journal of Clinical Investigation · 29
Non-decameric NLRP3 forms an MTOC-independent inflammasome
2023 · María Mateo-Tórtola, Inga V. Hochheiser, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 28
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ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux
2023 · Fátima Martín-Sánchez, Vincent Compan, et al. · The Journal of Cell Biology · 27
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A novel CD14high CD16high subset of peritoneal macrophages from cirrhotic patients is associated to an increased response to LPS
2016 · Antonio José Ruiz-Alcaraz, Ana Tapia-Abellán, et al. · Molecular Immunology · 26
Effective ex vivo inhibition of cryopyrin-associated periodic syndrome (CAPS)-associated mutant NLRP3 inflammasome by MCC950/CRID3
2022 · Alexander N R Weber, Ana Tapia-Abellán, et al. · Rheumatology · 24
Glycoconjugate expression on the cell wall of tps1/tps1 trehalose-deficient Candida albicans strain and implications for its interaction with macrophages
2011 · M. Martinez-Esparza, A. Tapia-Abellan, et al. · Glycobiology · 22
Isolation of functional mature peritoneal macrophages from healthy humans
2019 · Antonio J Ruiz‐Alcaraz, Helios Martínez‐Banaclocha, et al. · Immunology and Cell Biology · 21
Addendum: MCC950 closes the active conformation of NLRP3 to an inactive state
2021 · Ana Tapia-Abellán, Diego Angosto-Bazarra, et al. · Nature Chemical Biology · 13
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Regulatory role of PI3K-protein kinase B on the release of interleukin-1β in peritoneal macrophages from the ascites of cirrhotic patients
2014 · A Tapia-Abellán, A J Ruiz-Alcaraz, et al. · Clinical & Experimental Immunology · 12
Actionable heterogeneity of hepatocellular carcinoma therapy-induced senescence
2025 · Pujan Engels, Andras Szolek, et al. · Cancer Immunology Immunotherapy · 10
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Non-decameric NLRP3 reveals a TGN/MTOC-distal pathway of inflammasome activation
2026 · María Mateo-Tórtola, Inga V. Hochheiser, et al. · Nature Communications · 4
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NLRP3 acts as a direct sensor of intracellular potassium ions
2026 · Ana Tapia-Abellán, Lukas Funk, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
Measuring NLR Oligomerization III: Detection of NLRP3 and NLRC4 Complex by Bioluminescence Resonance Energy Transfer
2023 · Fátima Martín-Sánchez, Alejandro Peñín-Franch, et al. · Methods in molecular biology · 1
Author Correction: Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization
2020 · Alberto Baroja-Mazo, Vincent Compan, et al. · Scientific Reports · 1
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Works count: 34
Citation count: 1,516
H-index: 18
I10-index: 21
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