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Yunjia Chen

Genotype-Phenotype Correlation in NF1: Evidence for a More Severe Phenotype Associated with Missense Mutations Affecting NF1 Codons 844–848
2017 · Magdalena Koczkowska, Yunjia Chen, et al. · The American Journal of Human Genetics · 216
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Secreted protein prediction system combining CJ-SPHMM, TMHMM, and PSORT
2003 · Yunjia Chen, Peng Yu, et al. · Mammalian Genome · 215
Noradrenergic dysfunction in Alzheimer's disease
2015 · Mary Gannon, Pulin Che, et al. · Frontiers in Neuroscience · 209
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SPD--a web-based secreted protein database
2004 · Y. Chen · Nucleic Acids Research · 192
High Incidence of Noonan Syndrome Features Including Short Stature and Pulmonic Stenosis in Patients carrying NF1 Missense Mutations Affecting p.Arg1809: Genotype–Phenotype Correlation
2015 · Kitiwan Rojnueangnit, Jing Xie, et al. · Human Mutation · 188
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Clinical spectrum of individuals with pathogenic N F1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype–phenotype study in neurofibromatosis type 1
2019 · Magdalena Koczkowska, Tom Callens, et al. · Human Mutation · 135
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β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade
2020 · Fang Zhang, Mary Gannon, et al. · Science Translational Medicine · 133
Expanding the clinical phenotype of individuals with a 3-bp in-frame deletion of the NF1 gene (c.2970_2972del): an update of genotype–phenotype correlation
2018 · Magdalena Koczkowska, Tom Callens, et al. · Genetics in Medicine · 93
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α 2A adrenergic receptor promotes amyloidogenesis through disrupting APP-SorLA interaction
2014 · Yunjia Chen, Yin Peng, et al. · Proceedings of the National Academy of Sciences · 79
CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice
2013 · Yuelong Liu, Cristina Harmelink, et al. · Human Molecular Genetics · 60
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Effects of the β3-adrenoceptor (Adrb3) agonist SR58611A (amibegron) on serotonergic and noradrenergic transmission in the rodent: Relevance to its antidepressant/anxiolytic-like profile
2008 · Y. Claustre, M. Leonetti, et al. · Neuroscience · 59
The Antidepressant Desipramine Is an Arrestin-biased Ligand at the α2A-Adrenergic Receptor Driving Receptor Down-regulation in Vitro and in Vivo
2011 · Christopher Cottingham, Yunjia Chen, et al. · Journal of Biological Chemistry · 51
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The α2B‐adrenergic receptor is mutant in cortical myoclonus and epilepsy
2013 · Maurizio De Fusco, Riccardo Vago, et al. · Annals of Neurology · 43
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Neurabin Scaffolding of Adenosine Receptor and RGS4 Regulates Anti-Seizure Effect of Endogenous Adenosine
2012 · Yunjia Chen, Yin Liu, et al. · Journal of Neuroscience · 36
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Epitope-tagged Receptor Knock-in Mice Reveal That Differential Desensitization of α2-Adrenergic Responses Is because of Ligand-selective Internalization
2009 · Roujian Lu, Yong Li, et al. · Journal of Biological Chemistry · 34
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Epigenetic switch reshapes epithelial progenitor cell signatures and drives inflammatory pathogenesis in hidradenitis suppurativa
2023 · Lin Jin, Yunjia Chen, et al. · Proceedings of the National Academy of Sciences · 33
AG‐exclusion zone revisited: Lessons to learn from 91 intronic NF1 3′ splice site mutations outside the canonical AG‐dinucleotides
2020 · Katharina Wimmer, Esther Schamschula, et al. · Human Mutation · 33
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Enhanced Hypotensive, Bradycardic, and Hypnotic Responses to α2-Adrenergic Agonists in Spinophilin-Null Mice Are Accompanied by Increased G Protein Coupling to the α2A-Adrenergic Receptor
2010 · R. Lu, Y. Chen, et al. · Molecular Pharmacology · 29
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The amyloid precursor protein modulates α 2A ‐adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment
2017 · Fang Zhang, Mary Gannon, et al. · The FASEB Journal · 25
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
2020 · Lin Jin, Yunjia Chen, et al. · Nature Communications · 24
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Constitutional mismatch repair deficiency is the diagnosis in 0.41% of pathogenic NF1/SPRED1 variant negative children suspected of sporadic neurofibromatosis type 1
2020 · Juan A. Perez-Valencia, Richard Gallon, et al. · Genetics in Medicine · 23
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The in vivo specificity of synaptic Gβ and Gγ subunits to the α2a adrenergic receptor at CNS synapses
2019 · Yun Young Yim, Katherine M. Betke, et al. · Scientific Reports · 22
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Protein Kinase A Phosphorylation of Spinophilin Modulates Its Interaction with the α2A-Adrenergic Receptor (AR) and Alters Temporal Properties of α2AAR Internalization
2008 · Jianmin Xu, Yunjia Chen, et al. · Journal of Biological Chemistry · 21
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Neurabin scaffolding of adenosine receptor and RGS4 regulates anti‐seizure effect of endogenous adenosine
2012 · Yunjia Chen, Yin Liu, et al. · The FASEB Journal · 15
Genetic Variations of α2-Adrenergic Receptors Illuminate the Diversity of Receptor Functions
2011 · Christopher Cottingham, Huaping Chen, et al. · Current topics in membranes · 14
Works count: 81
Citation count: 2,117
H-index: 22
I10-index: 31
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