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Marcus Pickhardt

“Lest we forget you — methylene blue …”
2011 · R. Heiner Schirmer, Heike Adler, et al. · Neurobiology of Aging · 425
Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy
2005 · Inna Khlistunova, Jacek Biernat, et al. · Journal of Biological Chemistry · 366
Anthraquinones Inhibit Tau Aggregation and Dissolve Alzheimer's Paired Helical Filaments in Vitro and in Cells
2004 · Marcus Pickhardt, Zuzana Gazova, et al. · Journal of Biological Chemistry · 344
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Development of Tau Aggregation Inhibitors for Alzheimer's Disease
2009 · Bruno Bulic, Marcus Pickhardt, et al. · Angewandte Chemie International Edition · 287
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
2007 · Y. P. Wang, J. Biernat, et al. · Proceedings of the National Academy of Sciences · 216
Tau protein and tau aggregation inhibitors
2010 · Bruno Bulic, Marcus Pickhardt, et al. · Neuropharmacology · 191
Curcumin‐Derived Pyrazoles and Isoxazoles: Swiss Army Knives or Blunt Tools for Alzheimer's Disease?
2007 · Rajeshwar Narlawar, Marcus Pickhardt, et al. · ChemMedChem · 177
Rhodanine‐Based Tau Aggregation Inhibitors in Cell Models of Tauopathy
2007 · Bruno Bulic, Marcus Pickhardt, et al. · Angewandte Chemie International Edition · 164
Mechanistic Basis of Phenothiazine‐Driven Inhibition of Tau Aggregation
2013 · Elias Akoury, Marcus Pickhardt, et al. · Angewandte Chemie International Edition · 153
The Core of Tau-Paired Helical Filaments Studied by Scanning Transmission Electron Microscopy and Limited Proteolysis
2006 · Martin von Bergen, Stefan Barghorn, et al. · Biochemistry · 146
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau
2015 · Katja Hochgräfe, Astrid Sydow, et al. · Acta Neuropathologica Communications · 140
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Phenylthiazolyl-Hydrazide and Its Derivatives Are Potent Inhibitors of τ Aggregation and Toxicity in Vitro and in Cells
2007 · Marcus Pickhardt, Gregor Larbig, et al. · Biochemistry · 131
Progress and Developments in Tau Aggregation Inhibitors for Alzheimer Disease
2013 · Bruno Bulic, Marcus Pickhardt, et al. · Journal of Medicinal Chemistry · 119
Cellular and humoral immune response in progressive multifocal leukoencephalopathy
2001 · Frank Weber, Claudia Goldmann, et al. · Annals of Neurology · 105
Inhibition of Tau Filament Formation by Conformational Modulation
2013 · Elias Akoury, Michal Gajda, et al. · Journal of the American Chemical Society · 78
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Screening for Inhibitors of Tau Polymerization
2005 · Marcus Pickhardt, Martin Bergen, et al. · Current Alzheimer Research · 74
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies
2015 · Marcus Pickhardt, Thomas Neumann, et al. · Current Alzheimer Research · 64
Screening for Inhibitors of Tau Protein Aggregation into Alzheimer Paired Helical Filaments: A Ligand Based Approach Results in Successful Scaffold Hopping
2007 · Gregor Larbig, Marcus Pickhardt, et al. · Current Alzheimer Research · 59
N-Phenylamine Derivatives as Aggregation Inhibitors in Cell Models of Tauopathy
2007 · M. Pickhardt, J. Biernat, et al. · Current Alzheimer Research · 57
Analysis of the transcriptional control region in progressive multifocal leukoencephalopathy
2000 · Beatriz Vaz, Paola Cinque, et al. · Journal of NeuroVirology · 57
Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease
2016 · Christina Dammers, Deniz Yolcu, et al. · PLoS ONE · 50
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Structural Basis of Small Molecule Targetability of Monomeric Tau Protein
2018 · Róbert Kiss, Georgina Csizmadia, et al. · ACS Chemical Neuroscience · 35
Inhibition of Tau Aggregation in Cell Models of Tauopathy
2007 · Inna Khlistunova, Marcus Pickhardt, et al. · Current Alzheimer Research · 33
N′-Benzylidene-Benzohydrazides as Novel and Selective Tau-PHF Ligands
2011 · Ali Taghavi, Samir Nasir, et al. · Journal of Alzheimer s Disease · 32
Entwicklung von Inhibitoren der Tau‐Aggregation bei Morbus Alzheimer
2009 · Bruno Bulic, Marcus Pickhardt, et al. · Angewandte Chemie · 25
Works count: 49
Citation count: 3,680
H-index: 25
I10-index: 31
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