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Luke M. Healy
Observed names:
Healy, Luke,
Healy, Luke M.,
L.M. Healy,
Luke Healy,
Luke M Healy,
Luke Michael Healy
show all 6
Institutions:
Montreal Neurological Institute and Hospital,
McGill University
Observed institutions:
Montreal Neurological Institute and Hospital,
Trinity College Dublin,
McGill University,
University of Pennsylvania
ORCID:
0000-0001-9496-2216
Observed ORCID:
0000-0001-9496-2216
OpenAlex ID:
A5030216414
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
2017
·
Edsel M. Abud
, Ricardo N. Ramirez
, et al.
·
Neuron
·
1,148
PDF
Microglial control of astrocytes in response to microbial metabolites
2018
·
Veit Rothhammer
, Davis M. Borucki
, et al.
·
Nature
·
1,044
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39
2019
·
Maisa C. Takenaka
, Galina Gabriely
, et al.
·
Nature Neuroscience
·
516
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
2016
·
Konrad Gabrusiewicz
, Benjamin Rodriguez
, et al.
·
JCI Insight
·
445
PDF
Roles of microglia in brain development, tissue maintenance and repair
2015
·
Mackenzie A. Michell-Robinson
, Hanane Touil
, et al.
·
Brain
·
425
Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo
2019
·
Jonathan Hasselmann
, Morgan A. Coburn
, et al.
·
Neuron
·
377
PDF
Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes
2017
·
Konrad Gabrusiewicz
, Xu Li
, et al.
·
OncoImmunology
·
349
PDF
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates
2021
·
Jinar Rostami
, Tobias Mothes
, et al.
·
Journal of Neuroinflammation
·
224
PDF
Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain
2020
·
Jinar Rostami
, Grammatiki Fotaki
, et al.
·
Journal of Neuroinflammation
·
210
PDF
Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury
2018
·
Andrew D. Greenhalgh
, Juan G. Zarruk
, et al.
·
PLoS Biology
·
207
PDF
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation
2017
·
Veit Rothhammer
, Jessica E. Kenison
, et al.
·
Proceedings of the National Academy of Sciences
·
195
Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans
2017
·
David R Owen
, Nehal Narayan
, et al.
·
Journal of Cerebral Blood Flow & Metabolism
·
194
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
2023
·
Erik Nutma
, Nurun Fancy
, et al.
·
Nature Communications
·
192
PDF
Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain
2022
·
Shannon Tansley
, Sonali Uttam
, et al.
·
Nature Communications
·
178
PDF
MerTK Is a Functional Regulator of Myelin Phagocytosis by Human Myeloid Cells
2016
·
Luke M Healy
, Gabrielle Perron
, et al.
·
The Journal of Immunology
·
173
Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
2019
·
Carl Laflamme
, Paul M McKeever
, et al.
·
eLife
·
155
The role of glial cells in multiple sclerosis disease progression
2022
·
Luke M. Healy
, Jo Anne Stratton
, et al.
·
Nature Reviews Neurology
·
152
Lesion stage-dependent causes for impaired remyelination in MS
2020
·
Katharina Heß
, Laura Starost
, et al.
·
Acta Neuropathologica
·
138
PDF
pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis
2019
·
David Kremer
, Joel Gruchot
, et al.
·
Proceedings of the National Academy of Sciences
·
119
Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis
2016
·
Rui Li
, Ayman Rezk
, et al.
·
Frontiers in Immunology
·
98
PDF
USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation
2016
·
Sabrina Torre
, Maria J Polyak
, et al.
·
Nature Immunology
·
95
Sphingosine 1‐phosphate receptors regulate TLR 4‐induced CXCL 5 release from astrocytes and microglia
2018
·
Sinead A. O'Sullivan
, Catherine O'Sullivan
, et al.
·
Journal of Neurochemistry
·
83
PDF
Effects of fumarates on circulating and CNS myeloid cells in multiple sclerosis
2015
·
Mackenzie A. Michell‐Robinson
, Craig S. Moore
, et al.
·
Annals of Clinical and Translational Neurology
·
74
PDF
Microglia Diversity in Health and Multiple Sclerosis
2020
·
Sameera Zia
, Khalil S. Rawji
, et al.
·
Frontiers in Immunology
·
70
PDF
Cross-talk between B cells, microglia and macrophages, and implications to central nervous system compartmentalized inflammation and progressive multiple sclerosis
2023
·
Hanane Touil
, Rui Li
, et al.
·
EBioMedicine
·
69
PDF
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Works count:
127
Citation count:
7,945
H-index:
36
I10-index:
56
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