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Rajamanikkam Kamaraj

Observed names: Kamaraj RAJAMANIKKAM, Kamaraj Rajamanikkam, Kamaraj, Rajamanikkam
Institution: Charles University
ORCID: 0000-0001-7115-0178
Observed ORCID: 0000-0001-7115-0178
OpenAlex ID: A5030722768
A review on pharmacological activities and synergistic effect of quercetin with small molecule agents
2021 · Haoyang Zou, Haiqing Ye, et al. · Phytomedicine · 208
Dietary phytochemicals as modulators of human pregnane X receptor
2021 · Jie Zhang, Petr Pavek, et al. · Critical Reviews in Food Science and Nutrition · 55
Targeted Protein Degradation (TPD) for Immunotherapy: Understanding Proteolysis Targeting Chimera-Driven Ubiquitin-Proteasome Interactions
2024 · Rajamanikkam Kamaraj, Subhrojyoti Ghosh, et al. · Bioconjugate Chemistry · 37
Allosteric Antagonism of the Pregnane X Receptor (PXR): Current-State-of-the-Art and Prediction of Novel Allosteric Sites
2022 · Rajamanikkam Kamaraj, Martin Drastik, et al. · Cells · 19
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The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model
2025 · Jan Dusek, Ivana Mejdrová, et al. · Nature Communications · 17
Rifampicin and its derivatives: stability, disposition, and affinity towards pregnane X receptor employing 2D and 3D primary human hepatocytes
2024 · Tomas Smutny, Lucie Smutna, et al. · Biochemical Pharmacology · 13
Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific 68Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors
2022 · Pavel Barta, Rajamanikkam Kamaraj, et al. · Bioconjugate Chemistry · 10
Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation
2025 · Rajamanikkam Kamaraj, Ivana Mejdrová, et al. · Journal of Medicinal Chemistry · 9
The “specific” P-glycoprotein inhibitor zosuquidar (LY335979) also weakly inhibits human organic cation transporters
2024 · Gzona Bajraktari-Sylejmani, Rajamanikkam Kamaraj, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 9
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Coelomic Fluid of Earthworm, Eudrilus Eugeniae, Inhibits the Growth of Fungal Hyphae, in Vitro
2019 · Chandran Rajesh, Kamaraj Rajamanikkam, et al. · International Journal of Engineering and Advanced Technology · 9
Rifabutin but not rifampicin can partly out-balance P-glycoprotein induction by concurrent P-glycoprotein inhibition through high affinity binding to the inhibitory site
2023 · Lottida Phondeth, Rajamanikkam Kamaraj, et al. · Archives of Toxicology · 8
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Earthworm, a novel in vivo system to validate antimitotic compounds
2019 · Kamaraj RAJAMANIKKAM, Subramanian ELAIYA RAJA, et al. · TURKISH JOURNAL OF ZOOLOGY · 8
Novel antagonists reveal the mechanism of PXR inhibition
2024 · Rajamanikkam Kamaraj, Petr Pavek · Trends in Pharmacological Sciences · 6
2-Substituted quinazolines: Partial agonistic and antagonistic ligands of the constitutive androstane receptor (CAR)
2023 · Zuzana Rania Brožová, Jan Dušek, et al. · European Journal of Medicinal Chemistry · 6
Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5-HT2C receptor agonists
2021 · Gangireddy Sujeevan Reddy, Rajamanikkam Kamaraj, et al. · Bioorganic Chemistry · 5
Dimethyl fumarate attenuates bile acid retention and liver fibrosis in a mouse model of cholestasis
2025 · Hana Lastuvkova, Ester Dohnalkova, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 4
Gene Expression Profiling of 1α,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic‐Metabolizing Genes
2022 · Petr Pavek, Jan Dusek, et al. · Molecular Nutrition & Food Research · 3
Pregnane X receptor antagonist MI-891 reduces hepatic triglycerides in PXR-CAR-CYP3A4/3A7-humanized mice
2026 · Klára Dohnalová, Rajamanikkam Kamaraj, et al. · Biomedicine & Pharmacotherapy · 1
Radiolabeled 15-mer peptide internalization is mediated by megalin (LRP2 receptor) in a CRISPR/Cas9-based LRP2 knockout human kidney cell model
2024 · Anna Durinova, Lucie Smutna, et al. · EJNMMI Radiopharmacy and Chemistry · 1
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PXR Inverse agonism relies on differential ligand-induced co-regulator reruitment
2026 · Azam Rashidian, Kronenberger, Thales, et al. · UEF eRepo (University of Eastern Finland)
PXR Inverse agonism relies on differential ligand-induced co-regulator reruitment
2026 · Azam Rashidian, Kronenberger, Thales, et al. · UEF eRepo (University of Eastern Finland)
The effect of salidroside, an active component of Rhodiola rosea, on the metabolic activity of rat and human cytochromes P450 in preclinical studies
2026 · Eva Klaskova, Jan Jurica, et al. · Pharmacological Reports
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Discovery and Pharmacological Profiling of Quinoline- and Quinoxaline-Based Phenoxypropanoic Acid Derivatives as Multitarget Modulators of PPARα, FXR, and LXRα receptors
2026 · Iuliia Melnikova, Galina Karabanovich, et al. · SSRN Electronic Journal
Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation
2025 · Kamaraj, Rajamanikkam, Mejdrova, Ivana, et al. · Zenodo (CERN European Organization for Nuclear Research)
In vitro and in silico evaluation of the interaction of yohimbine with drug transporters and cytochrome P450 isoenzymes
2025 · Gzona Bajraktari-Sylejmani, Rajamanikkam Kamaraj, et al. · European Journal of Pharmacology
Works count: 33
Citation count: 428
H-index: 9
I10-index: 7
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