Author

Sergio Serafini

Observed name: S. Serafini

Institutions: Novartis (Switzerland), Novartis Institutes for BioMedical Research

Observed institutions: Novartis (Switzerland), Novartis Institutes for BioMedical Research

OpenAlex ID: A5030739688

Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases

2008 · Philip Jones, Sergio Altamura, et al. · Bioorganic & Medicinal Chemistry Letters · 103

Biochemical characterization of a hepatitis C virus RNA-dependent RNA polymerase mutant lacking the C-terminal hydrophobic sequence

2000 · Licia Tomei, Alessandra Vitelli, et al. · Journal of General Virology · 80

A series of novel, potent, and selective histone deacetylase inhibitors

2006 · Philip Jones, Sergio Altamura, et al. · Bioorganic & Medicinal Chemistry Letters · 67

Identification of Novel, Selective, and Stable Inhibitors of Class II Histone Deacetylases. Validation Studies of the Inhibition of the Enzymatic Activity of HDAC4 by Small Molecules as a Novel Approach for Cancer Therapy

2009 · Jesus M. Ontoria, Sergio Altamura, et al. · Journal of Medicinal Chemistry · 64

Engineering human interleukin‐6 to obtain variants with strongly enhanced bioactivity.

1996 · C. Toniatti, A. Cabibbo, et al. · The EMBO Journal · 57

Identification of a series of 4-[3-(quinolin-2-yl)-1,2,4-oxadiazol-5-yl]piperazinyl ureas as potent smoothened antagonist hedgehog pathway inhibitors

2011 · Jesus M. Ontoria, Laura Llauger Bufi, et al. · Bioorganic & Medicinal Chemistry Letters · 29

Discovery of N-[(1-aryl-1H-indazol-5-yl)methyl]amides derivatives as smoothened antagonists for inhibition of the hedgehog pathway

2009 · Gabriella Dessole, Danila Branca, et al. · Bioorganic & Medicinal Chemistry Letters · 25

Studies of the metabolic stability in cells of 5-(trifluoroacetyl)thiophene-2-carboxamides and identification of more stable class II histone deacetylase (HDAC) inhibitors

2008 · Rita Scarpelli, Annalise Di Marco, et al. · Bioorganic & Medicinal Chemistry Letters · 25

Multiplexed Reporter Gene Assays: Monitoring the Cell Viability and the Compound Kinetics on Luciferase Activity

2011 · Marie-Cecile Didiot, Sergio Serafini, et al. · SLAS DISCOVERY · 17

A High-Throughput Radiometric Assay for Hepatitis C Virus NS3 Protease

1999 · Mauro Cerretani, Laura Di Renzo, et al. · Analytical Biochemistry · 14

Optimization of a series of potent and selective ketone histone deacetylase inhibitors

2008 · Giovanna Pescatore, Olaf Kinzel, et al. · Bioorganic & Medicinal Chemistry Letters · 12

Works count: 11

Citation count: 493

H-index: 11

I10-index: 11