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Toshiaki Tsuchitani

Observed names: Tsuchitani, Toshiaki, ツチタニ, トシアキ
Institution: Keio University
ORCID: 0000-0002-7257-3196
Observed ORCID: 0000-0002-7257-3196
OpenAlex ID: A5030886085
Elucidating nonlinear pharmacokinetics of telmisartan: Integration of target‐mediated drug disposition and OATP1B3‐mediated hepatic uptake in a physiologically based model
2024 · Toshiaki Tsuchitani, Atsuko Tomaru, et al. · CPT Pharmacometrics & Systems Pharmacology · 15
Inhibitory Effects of Cranberry Juice and Its Components on Intestinal OATP1A2 and OATP2B1: Identification of Avicularin as a Novel Inhibitor
2022 · Tokio Morita, Takeshi Akiyoshi, et al. · Journal of Agricultural and Food Chemistry · 13
The Effects of Jabara Juice on the Intestinal Permeation of Fexofenadine
2023 · Hongye Han, Takeshi Akiyoshi, et al. · Biological and Pharmaceutical Bulletin · 4
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Rat-Specific Expression of Placental MATE1 Contributes to Species Difference in Fetal Transfer of Metformin and 1-Methyl-4-Phenylpyridinium
2025 · Ashukan Suzuki, Saki Noguchi, et al. · Molecular Pharmaceutics · 2
Bridging in vitro and clinical data: Experimental insights into the IC50 variability of dolutegravir as an organic cation transporter 2 inhibitor
2025 · Tomoki Koishikawa, Yukana Tomoda, et al. · Drug Metabolism and Disposition · 2
Trends of in vitro pharmacological potency and in vivo pharmacokinetics parameters of modern drugs: Can the therapeutic/subtherapeutic dose be estimated from in vitro Ki and pharmacokinetic parameters?
2024 · Toshiaki Tsuchitani, Motohiro Kato, et al. · Clinical and Translational Science · 2
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Digoxin absorption decreased independently of P-gp activity in rats with irinotecan-induced gastrointestinal damage
2021 · Toshiaki Tsuchitani, Takeshi Akiyoshi, et al. · Journal of Pharmaceutical Health Care and Sciences · 2
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Relative contributions of metabolic enzymes to systemic elimination can be estimated from clinical DDI studies: Validation using an in silico approach
2020 · Kana Koinuma, Toshiaki Tsuchitani, et al. · International Journal of Clinical Pharmacology and Therapeutics · 2
MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model
2026 · Toshiaki Tsuchitani, Rin Midorikawa, et al. · The Journal of Physiology · 1
Analysis of the Correlation Between Membrane Permeability in RPMI 2650 Cells and Human Nasal Absorption
2026 · Tokio Morita, Toshiaki Tsuchitani, et al. · AAPS PharmSciTech · 1
Using an online journal club to improve Asian speakers’ comfort in using English to discuss and understand research papers written in English
2022 · Masami Tsuchiya, Manit Saeteaw, et al. · Journal of Oncology Pharmacy Practice · 1
Mechanistic bottom-up estimation of passive drug absorption from the gastrointestinal tract: Comparison among primary cultured human intestinal cells, Caco-2 cells, artificial membrane, and animal scale-up
2022 · Toshiaki Tsuchitani, Takeshi Akiyoshi, et al. · International Journal of Clinical Pharmacology and Therapeutics · 1
Net Renal Drug Secretion Critically Requires Significant Contribution of Basal Uptake Transporters: Perspective From Mechanistic Kidney Model Simulation and Integration of Clinical and In Vitro Data
2026 · Toshiaki Tsuchitani, Masatoshi Tomi, et al. · CPT Pharmacometrics & Systems Pharmacology
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MCT1-mediated propionate transport across a trophoblast stem cell-derived human placental barrier model
2026 · Kohei Yamamoto, Rin Midorikawa, et al. · Placenta
Wnt/β-Catenin Activation Drives Broad Trophoblast Lineage Specification Beyond Syncytiotrophoblast layer-II
2026 · Takuro Ishinabe, Saki Noguchi, et al. · Placenta
Spatial Transcriptomic Landscape of the Murine Placental Labyrinth in the Absence of Maternal Microbiota
2026 · Taichi Miyagi, Takuro Ishinabe, et al. · Placenta
Mechanistic modeling of human ex vivo placental perfusion data for pravastatin and antipyrine to elucidate their transplacental permeability, interindividual variability, and relationship with cotyledon weight
2026 · Toshiaki Tsuchitani, Sakura Mizutani, et al. · Placenta
Mechanistic insights into edoxaban’s nonlinear pharmacokinetics and quinidine interaction via P-glycoprotein using physiologically based pharmacokinetic modeling
2026 · Wen Kou, Toshiaki Tsuchitani, et al. · Drug Metabolism and Disposition
Characterizing Apixaban Pharmacokinetics Through Physiologically‐Based Pharmacokinetic Modeling: Critical Role of Biliary Secretion and Enterohepatic Circulation in Humans
2025 · Toshiaki Tsuchitani, Wen Kou, et al. · CPT Pharmacometrics & Systems Pharmacology
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MFSD2A-mediated transplacental transfer of lysophosphatidylcholine-docosahexaenoic acid in mice
2025 · Masatoshi Tomi, Ami Ishii, et al. · Placenta
Role of placental MFSD2A on docosahexaenoic acid transfer to the fetus in mice
2025 · Ami Ishii, Saki Noguchi, et al. · Placenta
Trends in in vitro potency and PK parameters; can therapeutic doses be estimated from in vitro KI?
2025 · Toshiaki Tsuchitani, Motohiro Kato, et al. · Drug Metabolism and Pharmacokinetics
Bottom-up法による薬物の消化管吸収および消化管P-gpを介した薬物間相互作用の定量的予測 (要約)
2021 · ツチタニ, トシアキ, Tsuchitani, Toshiaki, et al. · KeiO Associated Repository of Academic Resources (Keio University)
Bottom-up法による薬物の消化管吸収および消化管P-gpを介した薬物間相互作用の定量的予測 (審査報告)
2021 · ツチタニ, トシアキ, Tsuchitani, Toshiaki, et al. · KeiO Associated Repository of Academic Resources (Keio University)
Bottom-up法による薬物の消化管吸収および消化管P-gpを介した薬物間相互作用の定量的予測 (要旨)
2021 · ツチタニ, トシアキ, Tsuchitani, Toshiaki, et al. · KeiO Associated Repository of Academic Resources (Keio University)
Works count: 30
Citation count: 46
H-index: 3
I10-index: 2
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