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Hetian Lei

Genome Analysis of the Ancient Tracheophyte Selaginella tamariscina Reveals Evolutionary Features Relevant to the Acquisition of Desiccation Tolerance
2018 · Zhichao Xu, Tianyi Xin, et al. · Molecular Plant · 150
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Genome editing abrogates angiogenesis in vivo
2017 · Xionggao Huang, Guohong Zhou, et al. · Nature Communications · 142
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A Novel Peptide Isolated from a Phage Display Library Inhibits Tumor Growth and Metastasis by Blocking the Binding of Vascular Endothelial Growth Factor to Its Kinase Domain Receptor
2002 · Lei Hetian, An Ping, et al. · Journal of Biological Chemistry · 116
Growth Factors Outside of the Platelet-derived Growth Factor (PDGF) Family Employ Reactive Oxygen Species/Src Family Kinases to Activate PDGF Receptor α and Thereby Promote Proliferation and Survival of Cells
2009 · Hetian Lei, Andrius Kazlauskas · Journal of Biological Chemistry · 102
Recent developments in our understanding of how platelet-derived growth factor (PDGF) and its receptors contribute to proliferative vitreoretinopathy
2009 · Hetian Lei, Marc-Andre Rheaume, et al. · Experimental Eye Research · 98
Protein Kinase A-dependent Translocation of Hsp90α Impairs Endothelial Nitric-oxide Synthase Activity in High Glucose and Diabetes
2007 · Hetian Lei, Annapurna Venkatakrishnan, et al. · Journal of Biological Chemistry · 96
PDGF Receptor-α Does Not Promote HCMV Entry into Epithelial and Endothelial Cells but Increased Quantities Stimulate Entry by an Abnormal Pathway
2012 · Adam L. Vanarsdall, Todd W. Wisner, et al. · PLoS Pathogens · 85
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Growth Factors Outside the PDGF Family Drive Experimental PVR
2009 · Hetian Lei, Gisela Velez, et al. · Investigative Ophthalmology & Visual Science · 79
PDGF receptors are activated in human epiretinal membranes
2008 · Jing Cui, Hetian Lei, et al. · Experimental Eye Research · 75
Suppression of tumor growth and metastasis by a VEGFR‐1 antagonizing peptide identified from a phage display library
2004 · Ping An, Hetian Lei, et al. · International Journal of Cancer · 70
N-Acetylcysteine Suppresses Retinal Detachment in an Experimental Model of Proliferative Vitreoretinopathy
2010 · Hetian Lei, Gisela Velez, et al. · American Journal Of Pathology · 69
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A Potential Role for PDGF-C in Experimental and Clinical Proliferative Vitreoretinopathy
2007 · Hetian Lei, Peter Hovland, et al. · Investigative Ophthalmology & Visual Science · 65
Heat Shock Protein 90α–Dependent Translocation of Annexin II to the Surface of Endothelial Cells Modulates Plasmin Activity in the Diabetic Rat Aorta
2004 · Hetian Lei, Giulio Romeo, et al. · Circulation Research · 65
Pathological Signaling via Platelet-Derived Growth Factor Receptor α Involves Chronic Activation of Akt and Suppression of p53
2011 · Hetian Lei, Gisela Velez, et al. · Molecular and Cellular Biology · 64
Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation
2017 · Xionggao Huang, Guohong Zhou, et al. · Investigative Ophthalmology & Visual Science · 61
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Expression of PDGFRα Is a Determinant of the PVR Potential of ARPE19 Cells
2011 · Hetian Lei, Marc-André Rhéaume, et al. · Investigative Ophthalmology & Visual Science · 56
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Exosomes mediate an epithelial‐mesenchymal transition cascade in retinal pigment epithelial cells: Implications for proliferative vitreoretinopathy
2020 · Yao Zhang, Kaizhe Wang, et al. · Journal of Cellular and Molecular Medicine · 48
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A Reactive Oxygen Species-Mediated, Self-Perpetuating Loop Persistently Activates Platelet-Derived Growth Factor Receptor α
2013 · Hetian Lei, Andrius Kazlauskas · Molecular and Cellular Biology · 48
AAV-CRISPR/Cas9–Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro
2017 · Wenyi Wu, Yajian Duan, et al. · Investigative Ophthalmology & Visual Science · 43
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A Novel Function of p53
2012 · Hetian Lei, Marc-Andre Rheaume, et al. · American Journal Of Pathology · 34
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PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis
2020 · Wenyi Wu, Guohong Zhou, et al. · Diabetes · 33
The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and Proliferation and Survival of Cells
2016 · Yajian Duan, Gaoen Ma, et al. · Journal of Biological Chemistry · 32
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Plasmin Is the Major Protease Responsible for Processing PDGF-C in the Vitreous of Patients with Proliferative Vitreoretinopathy
2008 · Hetian Lei, Gisela Velez, et al. · Investigative Ophthalmology & Visual Science · 28
Progress in the application of CRISPR: From gene to base editing
2018 · Wenyi Wu, Yanhui Yang, et al. · Medicinal Research Reviews · 27
RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology
2015 · Hetian Lei, Cynthia X. Qian, et al. · Molecular and Cellular Biology · 27
Works count: 113
Citation count: 2,219
H-index: 26
I10-index: 50
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