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Julien Sourimant

Structure of the Respiratory Syncytial Virus Polymerase Complex
2019 · Morgan S.A. Gilman, Cheng Liu, et al. · Cell · 218
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Visualizing the replication of respiratory syncytial virus in cells and in living mice
2014 · Marie-Anne Rameix-Welti, Ronan Le Goffic, et al. · Nature Communications · 174
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4′-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication
2022 · Julien Sourimant, Carolin M Lieber, et al. · Science · 131
Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets
2021 · Robert M. Cox, Josef D. Wolf, et al. · Nature Communications · 120
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Identification and Characterization of the Binding Site of the Respiratory Syncytial Virus Phosphoprotein to RNA-Free Nucleoprotein
2015 · Marie Galloux, Gaëlle Gabiane, et al. · Journal of Virology · 90
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Fine Mapping and Characterization of the L-Polymerase-Binding Domain of the Respiratory Syncytial Virus Phosphoprotein
2015 · Julien Sourimant, Marie-Anne Rameix-Welti, et al. · Journal of Virology · 78
Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses
2021 · Chengjin Ye, Kevin Chiem, et al. · Proceedings of the National Academy of Sciences · 52
SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model
2022 · Carolin M. Lieber, Robert M. Cox, et al. · Nature Communications · 50
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Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase
2020 · Robert M. Cox, Julien Sourimant, et al. · Nature Microbiology · 49
4’-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses
2023 · Carolin M Lieber, Megha Aggarwal, et al. · PLoS Pathogens · 44
Therapeutic targeting of measles virus polymerase with ERDRP-0519 suppresses all RNA synthesis activity
2021 · Robert M. Cox, Julien Sourimant, et al. · PLoS Pathogens · 38
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Development of an allosteric inhibitor class blocking RNA elongation by the respiratory syncytial virus polymerase complex
2018 · Robert M. Cox, Mart Toots, et al. · Journal of Biological Chemistry · 38
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Orally efficacious lead of the AVG inhibitor series targeting a dynamic interface in the respiratory syncytial virus polymerase
2022 · Julien Sourimant, Carolin M. Lieber, et al. · Science Advances · 35
Progress and pitfalls of a year of drug repurposing screens against COVID-19
2021 · Julien Sourimant, Megha Aggarwal, et al. · Current Opinion in Virology · 26
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Organization, Function, and Therapeutic Targeting of the Morbillivirus RNA-Dependent RNA Polymerase Complex
2016 · Julien Sourimant, Richard Plemper · Viruses · 25
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The Unstructured Paramyxovirus Nucleocapsid Protein Tail Domain Modulates Viral Pathogenesis through Regulation of Transcriptase Activity
2018 · Vidhi D. Thakkar, Robert M. Cox, et al. · Journal of Virology · 24
SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy
2021 · Alexander M. Horspool, Chengjin Ye, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 22
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A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo
2021 · Kevin Chiem, Desarey Morales Vasquez, et al. · Journal of Virology · 19
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Viral evolution identifies a regulatory interface between paramyxovirus polymerase complex and nucleocapsid that controls replication dynamics
2020 · Julien Sourimant, Vidhi D. Thakkar, et al. · Science Advances · 18
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Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice
2022 · Ting Y. Wong, Alexander M. Horspool, et al. · Journal of Virology · 17
Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus
2020 · Nicole Pribut, Thomas M. Kaiser, et al. · ACS Infectious Diseases · 17
Pre-assembly of biomolecular condensate seeds drives RSV replication
2026 · Dhanushika Ratnayake, Marie Galloux, et al. · Nature · 10
High-Throughput Screening Assay to Identify Small Molecule Inhibitors of Marburg Virus VP40 Protein
2020 · Priya Luthra, Manu Anantpadma, et al. · ACS Infectious Diseases · 8
Can plitidepsin be used as an antiviral against RSV?
2025 · Charlotte Estampes, Jenna Fix, et al. · mSphere · 3
Direct interaction between RSV polymerase L and active Rab11a mediates viral ribonucleoprotein transport to assembly sites
2026 · Claire Giry, Ana Joaquina Jimenez, et al. · PLoS Pathogens · 2
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Works count: 50
Citation count: 1,310
H-index: 18
I10-index: 22
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