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Jagadeesh Babu Thentu

Observed institution: Suven Life Sciences (India)
ORCID: 0000-0002-1840-5263
Observed ORCID: 0000-0002-1840-5263
OpenAlex ID: A5031141885
Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression
2020 · Ramakrishna Nirogi, Abdul Rasheed Mohammed, et al. · Journal of Medicinal Chemistry · 28
Discovery and Preclinical Characterization of Usmarapride (SUVN-D4010): A Potent, Selective 5-HT4 Receptor Partial Agonist for the Treatment of Cognitive Deficits Associated with Alzheimer’s Disease
2021 · Ramakrishna Nirogi, Abdul Rasheed Mohammed, et al. · Journal of Medicinal Chemistry · 18
Ropanicant (SUVN-911), an α4β2 nicotinic acetylcholine receptor antagonist intended for the treatment of depressive disorders: pharmacological, behavioral, and neurochemical characterization
2022 · Ramakrishna Nirogi, Renny Abraham, et al. · Psychopharmacology · 8
Usmarapride (SUVN-D4010), a 5-HT4 receptor partial agonist for the potential treatment of Alzheimer's disease: Behavioural, neurochemical and pharmacological profiling
2023 · Ramakrishna Nirogi, Venkata Ramalingayya Grandhi, et al. · European Journal of Pharmacology · 7
A definite measure of occupancy exposures, seeking with non-radiolabeled in vivo 5-HT2A receptor occupancy and in vitro free fractions
2018 · Gopinadh Bhyrapuneni, Jagadeesh Babu Thentu, et al. · Journal of Receptors and Signal Transduction · 6
Simultaneous in-vivo receptor occupancy assays for serotonin 1A, 2A, and dopamine 2 receptors with the use of non-radiolabelled tracers: Proposed method in screening antipsychotics
2017 · Jagadeesh Babu Thentu, Ramakrishna Nirogi, et al. · Journal of Pharmacological and Toxicological Methods · 6
1‐[2‐(1‐Cyclobutylpiperidin‐4‐yloxy)‐6,7‐dihydro‐4H‐thiazolo[5,4‐c]pyridin‐5‐yl]propan‐1‐one: a Histamine H3 Receptor Inverse Agonist with Efficacy in Animal Models of Cognition
2021 · Anil Karbhari Shinde, Rajesh Kumar Badange, et al. · ChemMedChem · 4
Evaluation of monoamine oxidase A and B type enzyme occupancy using non-radiolabelled tracers in rat brain
2021 · Jagadeesh Babu Thentu, Gopinadh Bhyrapuneni, et al. · Neurochemistry International · 4
P1‐310: Suvn‐g3031, an h3 receptor inverse agonist, produces procognitive effects without affecting sleep in preclinical models
2015 · Vijay S. Benade, Saivishal Daripelli, et al. · Alzheimer s & Dementia · 4
LC–MS/MS Method for Quantification of 3,4-dihydroxyphenylglycol, a Norepinephrine Metabolite in Plasma and Brain Regions
2019 · Naga Surya Prakash Padala, Devender Reddy Ajjala, et al. · Bioanalysis · 3
Assessment of sigma-1 receptor occupancy in mice with non-radiolabelled FTC-146 as a tracer
2018 · Gopinadh Bhyrapuneni, Jagadeesh Babu Thentu, et al. · Journal of Receptors and Signal Transduction · 2
0051 Samelisant, a H3 Receptor Inverse Agonist for the Potential Treatment of Excessive Daytime Sleepiness in Parkinson’s Disease
2023 · Ramakrishna Nirogi, Vijay Benade, et al. · SLEEP · 1
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5‐HT1A Receptor Agonist, SUVN‐N9503012 for the Treatment of Dementia and Associated Neuropsychiatric Disorders
2023 · Renny Abraham, Surendra Petlu, et al. · Alzheimer s & Dementia
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Usmarapride Oxalate (SUVN‐D4010): A Serotonin‐4 Receptor Partial Agonist for the Treatment of Cognitive Disorders
2022 · Renny Abraham, Ramkumar Subramanian, et al. · Alzheimer s & Dementia
0265 Samelisant (SUVN-G3031), a Histamine H3 Receptor Inverse Agonist in Animal Models of Narcolepsy
2022 · Vijay Benade, Renny Abraham, et al. · SLEEP
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P2‐062: Assessment of Central and Peripheral 5‐Ht4 Receptor Occupancy in Rats
2016 · Jagadeesh Babu Thentu, Gopinadh Bhyrapuneni, et al. · Alzheimer s & Dementia
In Vivo Brain Receptor Occupancy for Pde‐10 Receptors in Mice and Rats Using Non‐radiolabeled Tracer
2014 · Gopinadh Bhyrapuneni, Jagadeesh Babu Thentu, et al. · Alzheimer s & Dementia
Works count: 17
Citation count: 91
H-index: 6
I10-index: 2
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