Get started
Author

Anthony R Bradley

Observed names: A. Bradley, A. R. Bradley, A.R. Bradley, Anthony Bradley, Anthony R. Bradley, Anthony R. Bradley, Bradley, Anthony, Bradley, Anthony R.
Observed institutions: University of Liverpool, San Diego Supercomputer Center, University of Johannesburg, University of Cambridge, Diamond Light Source, Structural Genomics Consortium, University of California San Diego, University of Oxford, Research Complex at Harwell, Cambridge Crystallographic Data Centre, Worldwide Protein Data Bank, Kennedy Institute of Rheumatology
ORCID: 0000-0002-0881-3490
Observed ORCID: 0000-0002-0881-3490
OpenAlex ID: A5031260889
OUP accepted manuscript
2016 · Peter W. Rose, Andreas Prlić, et al. · Nucleic Acids Research · 796
PDF
NGL viewer: web-based molecular graphics for large complexes
2018 · Alexander S Rose, Anthony R Bradley, et al. · Bioinformatics · 492
Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening
2019 · Efrat Resnick, Anthony Bradley, et al. · Journal of the American Chemical Society · 325
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density
2017 · Nicholas M. Pearce, Tobias Krojer, et al. · Nature Communications · 301
PDF
Deep Generative Models for 3D Linker Design
2020 · Fergus Imrie, Anthony R. Bradley, et al. · Journal of Chemical Information and Modeling · 268
A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain
2015 · Oakley B. Cox, Tobias Krojer, et al. · Chemical Science · 168
PDF
Protein Family-Specific Models Using Deep Neural Networks and Transfer Learning Improve Virtual Screening and Highlight the Need for More Data
2018 · Fergus Imrie, Anthony R. Bradley, et al. · Journal of Chemical Information and Modeling · 125
PDF
Deep generative design with 3D pharmacophoric constraints
2021 · Fergus Imrie, Thomas E. Hadfield, et al. · Chemical Science · 113
PDF
Generating property-matched decoy molecules using deep learning
2021 · Fergus Imrie, Anthony R Bradley, et al. · Bioinformatics · 106
PDF
Web-based molecular graphics for large complexes
2016 · Alexander S. Rose, Anthony R. Bradley, et al. · international conference on 3D web technology · 85
Testing the limits of SMILES-based de novo molecular generation with curriculum and deep reinforcement learning
2023 · Maranga Mokaya, Fergus Imrie, et al. · Nature Machine Intelligence · 49
BioJava 5: A community driven open-source bioinformatics library
2019 · Aleix Lafita, Spencer Bliven, et al. · PLoS Computational Biology · 43
PDF
MMTF—An efficient file format for the transmission, visualization, and analysis of macromolecular structures
2017 · Anthony R. Bradley, Alexander S. Rose, et al. · PLoS Computational Biology · 43
PDF
Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites
2017 · Nicholas M. Pearce, Anthony R. Bradley, et al. · Structural Dynamics · 35
PDF
The druggable genome: Twenty years later
2022 · Chris J. Radoux, Francesca Vianello, et al. · Frontiers in Bioinformatics · 22
PDF
Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
2020 · Sarah L. Kidd, Elaine Fowler, et al. · Chemical Science · 21
PDF
Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design
2020 · Peter R. Curran, Chris J. Radoux, et al. · Journal of Chemical Information and Modeling · 19
Fragment Hotspot Mapping to Identify Selectivity-Determining Regions between Related Proteins
2022 · Mihaela D. Smilova, Peter R. Curran, et al. · Journal of Chemical Information and Modeling · 15
The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery
2017 · Anthony R. Bradley, Aude Echalier, et al. · Essays in Biochemistry · 15
PDF
Towards an efficient compression of 3D coordinates of macromolecular structures
2017 · Yana Valasatava, Anthony R. Bradley, et al. · PLoS ONE · 14
PDF
Binding‐Site Purification of Actives (B‐SPA) Enables Efficient Large‐Scale Progression of Fragment Hits by Combining Multi‐Step Array Synthesis With HT Crystallography
2025 · Harold Grosjean, Anthony Aimon, et al. · Angewandte Chemie International Edition · 13
PDF
OOMMPPAA: A Tool To Aid Directed Synthesis by the Combined Analysis of Activity and Structural Data
2014 · Anthony R. Bradley, Ian D. Wall, et al. · Journal of Chemical Information and Modeling · 9
PDF
WONKA: objective novel complex analysis for ensembles of protein–ligand structures
2015 · A. R. Bradley, I. D. Wall, et al. · Journal of Computer-Aided Molecular Design · 8
PDF
Coverage Score: A Model Agnostic Method to Efficiently Explore Chemical Space
2022 · Daniel J. Woodward, Anthony R. Bradley, et al. · Journal of Chemical Information and Modeling · 7
Deliberately Losing Control of C−H Activation Processes in the Design of Small‐Molecule‐Fragment Arrays Targeting Peroxisomal Metabolism
2020 · Raysa Khan Tareque, Storm Hassell‐Hart, et al. · ChemMedChem · 7
Works count: 120
Citation count: 3,137
H-index: 17
I10-index: 21
Year
Topic
Type