Author

Sean Lang

Institutions: St. Michael's Hospital, University of Toronto, Keenan Research Centre for Biomedical Science, Canadian Blood Services

Observed institutions: St. Michael's Hospital, University of Toronto, University of Toronto Scarborough, Keenan Research Centre for Biomedical Science, Canadian Blood Services

OpenAlex ID: A5031271425

Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries

2012 · Conglei Li, June Li, et al. · Advances in Hematology · 155

Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia

2017 · Issaka Yougbaré, Wei-She Tai, et al. · Nature Communications · 123

Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage

2015 · Issaka Yougbaré, Sean Lang, et al. · Journal of Clinical Investigation · 122

Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression

2009 · Hong Yang, Sean Lang, et al. · Blood · 106

Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy

2010 · Pingguo Chen, Conglei Li, et al. · Blood · 103

The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies

2011 · Conglei Li, Siavash Piran, et al. · Journal of Clinical Investigation · 96

Platelets in Thrombosis and Hemostasis: Old Topic with New Mechanisms

2012 · Yiming Wang, Marc Andrews, et al. · Cardiovascular & Haematological Disorders - Drug Targets · 76

Co-stimulation with LPS or Poly I:C markedly enhances the anti-platelet immune response and severity of fetal and neonatal alloimmune thrombocytopenia

2013 · Conglei Li, Pingguo Chen, et al. · Thrombosis and Haemostasis · 28

Fc-independent Phagocytosis: Implications for IVIG and other Therapies in Immune-mediated Thrombocytopenia

2013 · June Li, Dianne van der Wal, et al. · Cardiovascular & Haematological Disorders - Drug Targets · 23

Desialylation: A Novel Platelet Clearance Mechanism and a Potential New Therapeutic Target in Anti-GPIb Antibody Mediated Thrombocytopenia

2012 · Dianne E. van Der Wal, Guangheng Zhu, et al. · Blood · 14

Maternal Anti-Platelet β3 Integrin Antibodies Impair Angiogenesis and Cause Intracranial Hemorrhage in Fetal and Neonatal Alloimmune Thrombocytopenia

2014 · Yougbare Issaka, Sean Lang, et al. · Blood

Abstract 225: Apolipoprotein A-IV Is a ß3 Integrin Ligand and an Endogenous Inhibitor of Platelets: Novel Mechanisms of Prevention and Treatment for Atherothrombosis

2014 · Xiaohong Xu, Lining Ju, et al. · Arteriosclerosis Thrombosis and Vascular Biology

Pathogenesis of Fetal and Neonatal Immune Thrombocytopenia: Role of Anti-Beta3 Integrin Antibodies in Vascular Injury and Angiogenesis

2013 · Sean Lang · TSpace (University of Toronto)

Maternal Immune Response to Fetal Platelet GPIbα Causes More Frequent Miscarriage in An Animal Model: A Potential Explanation for Low Reported Incidence of Fetal and Neonatal Immune Thrombocytopenia Mediated by Anti-GPIbα Antibodies.

2008 · Conglei Li, Siavash Piran, et al. · Blood

Engagement of Fibrinogen and β3 Integrin Is Required for Maintenance of Platelet Intracellular and Cell Surface P-Selectin Expression

2008 · Hong Yang, Sean Lang, et al. · Blood

Works count: 15

Citation count: 846

H-index: 10

I10-index: 10