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Fréderic Ausseil

DNA methylation inhibitors in cancer: Recent and future approaches
2012 · Christina Gros, Jacques Fahy, et al. · Biochimie · 248
Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer
2012 · Isabelle Dufau, Céline Frongia, et al. · BMC Cancer · 145
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Parthenolide Inhibits Tubulin Carboxypeptidase Activity
2007 · Xavier Fonrose, Frédéric Ausseil, et al. · Cancer Research · 127
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Bioactive flavonoids of Tanacetum parthenium revisited
2003 · Christophe Long, Pierre Sauleau, et al. · Phytochemistry · 88
Design, Synthesis and Biological Evaluation of 4‐Amino‐ N ‐(4‐aminophenyl)benzamide Analogues of Quinoline‐Based SGI‐1027 as Inhibitors of DNA Methylation
2014 · Elodie Rilova, Alexandre Erdmann, et al. · ChemMedChem · 76
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Alisiaquinones and Alisiaquinol, Dual Inhibitors of Plasmodium falciparum Enzyme Targets from a New Caledonian Deep Water Sponge
2008 · Denis Desoubzdanne, Laurence Marcourt, et al. · Journal of Natural Products · 76
New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors
2014 · Christina Gros, Laurence Fleury, et al. · Journal of Biological Chemistry · 73
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Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells
2017 · Ludovic Halby, Yoann Menon, et al. · Journal of Medicinal Chemistry · 70
Physalin B, a novel inhibitor of the ubiquitin-proteasome pathway, triggers NOXA-associated apoptosis
2008 · Isabelle Vandenberghe, Laurent Créancier, et al. · Biochemical Pharmacology · 63
Modulation of Cellular Response to Cisplatin by a Novel Inhibitor of DNA Polymerase β
2005 · F. Boudsocq, P. Benaim, et al. · Molecular Pharmacology · 56
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
2019 · Clemens Zwergel, Michael Schnekenburger, et al. · Clinical Epigenetics · 54
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Development of a universal radioactive DNA methyltransferase inhibition test for high-throughput screening and mechanistic studies
2013 · Christina Gros, Laura Chauvigné, et al. · Nucleic Acids Research · 53
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Properly Substituted Analogues of BIX-01294 Lose Inhibition of G9a Histone Methyltransferase and Gain Selective Anti-DNA Methyltransferase 3A Activity
2014 · Dante Rotili, Domenico Tarantino, et al. · PLoS ONE · 43
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Design and synthesis of new non nucleoside inhibitors of DNMT3A
2015 · Alexandre Erdmann, Yoann Menon, et al. · Bioorganic & Medicinal Chemistry · 31
Identification of Chiral Alkenyl‐ and Alkynylcarbinols as Pharmacophores for Potent Cytotoxicity
2013 · Dounia El Arfaoui, Dymytrii Listunov, et al. · ChemMedChem · 31
Preparation of phenylethylbenzamide derivatives as modulators of DNMT3 activity
2013 · Anzhelika Kabro, Hugo Lachance, et al. · MedChemComm · 30
High-Throughput Bioluminescence Screening of Ubiquitin-Proteasome Pathway Inhibitors from Chemical and Natural Sources
2006 · Frederic Ausseil, Arnaud Samson, et al. · SLAS DISCOVERY · 28
Heteronemin as a Protein Farnesyl Transferase Inhibitor
2004 · Véronique Ledroit, Cécile Debitus, et al. · Pharmaceutical Biology · 28
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Dichapetalins from Dichapetalum species and their cytotoxic properties
2013 · Christophe Long, Yannick Aussagues, et al. · Phytochemistry · 27
Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells
2016 · Jean-Marc Gregoire, Laurence Fleury, et al. · BMC Cancer · 24
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Meroterpenes from Dichrostachys cinerea Inhibit Protein Farnesyl Transferase Activity
2009 · Christophe Long, Laurence Marcourt, et al. · Journal of Natural Products · 22
The CERT antagonist HPA-12: First practical synthesis and individual binding evaluation of the four stereoisomers
2015 · Cécile Santos, Laurence Fleury, et al. · Bioorganic & Medicinal Chemistry · 21
Asymmetric Synthesis and Binding Study of New Long‐Chain HPA‐12 Analogues as Potent Ligands of the Ceramide Transfer Protein CERT
2016 · Andrej Ďuriš, Adam Daïch, et al. · Chemistry - A European Journal · 20
Identification and Optimization of Hydrazone-Gallate Derivatives as Specific Inhibitors of DNA Methyltransferase 3A
2016 · Alexandre Erdmann, Yoann Menon, et al. · Future Medicinal Chemistry · 18
Proteasome Inhibitors from Neoboutonia melleri
2011 · Christophe Long, Joséphine Beck, et al. · Journal of Natural Products · 17
Works count: 46
Citation count: 1,533
H-index: 21
I10-index: 27
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