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Manish Datt

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
2017 · Jaya Sangodkar, Abbey Perl, et al. · Journal of Clinical Investigation · 192
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Apigenin blocks IKKα activation and suppresses prostate cancer progression
2015 · Sanjeev Shukla, Rajnee Kanwal, et al. · Oncotarget · 107
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Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4+ T Lymphocytes
2013 · Uri R. Mbonye, Giridharan Gokulrangan, et al. · PLoS Pathogens · 95
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Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
2016 · Rajnee Kanwal, Manish Datt, et al. · PLoS ONE · 69
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Safranal inhibits NLRP3 inflammasome activation by preventing ASC oligomerization
2021 · Mehak Gupta, Abubakar Wani, et al. · Toxicology and Applied Pharmacology · 25
Structural Analysis of Proinsulin Hexamer Assembly by Hydroxyl Radical Footprinting and Computational Modeling
2011 · Janna G. Kiselar, Manish Datt, et al. · Journal of Biological Chemistry · 23
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Identification of a New Exosite Involved in Catalytic Turnover by the Streptokinase-Plasmin Activator Complex during Human Plasminogen Activation
2009 · Rachna Aneja, Manish Datt, et al. · Journal of Biological Chemistry · 21
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Evolutionary and structural annotation of disease-associated mutations in human aminoacyl-tRNA synthetases
2014 · Manish Datt, Amit Sharma · BMC Genomics · 20
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Novel and unique domains in aminoacyl-tRNA synthetases from human fungal pathogens Aspergillus niger, Candida albicans and Cryptococcus neoformans
2014 · Manish Datt, Amit Sharma · BMC Genomics · 17
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Multiple Exosites Distributed across the Three Domains of Streptokinase Co-Operate to Generate High Catalytic Rates in the Streptokinase–Plasmin Activator Complex
2013 · Rachna Aneja, Manish Datt, et al. · Biochemistry · 17
Equilibrium binding and kinetic characterization of putative tetracycline repressor family transcription regulator Fad35R from Mycobacterium tuberculosis
2012 · Sushma Anand, Vijay Singh, et al. · FEBS Journal · 17
Role of the 88–97 loop in plasminogen activation by streptokinase probed through site-specific mutagenesis
2008 · Suman Yadav, Manish Datt, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 17
Molecular cloning, characterization, and engineering of xylitol dehydrogenase from Debaryomyces hansenii
2012 · Dipanwita Biswas, Manish Datt, et al. · Applied Microbiology and Biotechnology · 16
Plant Defense Peptides: Exploring the Structure–Function Correlation for Potential Applications in Drug Design and Therapeutics
2025 · Hrutuja Shirsat, Manish Datt, et al. · ACS Omega · 15
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Conformational landscapes for KMSKS loop in tyrosyl-tRNA synthetases
2014 · Manish Datt, Amit Sharma · Journal of Structural and Functional Genomics · 14
A Single-Amino-Acid Substitution in the C Terminus of PhoP Determines DNA-Binding Specificity of the Virulence-Associated Response Regulator from Mycobacterium tuberculosis
2010 · Arijit Kumar Das, Anuj Pathak, et al. · Journal of Molecular Biology · 14
Genome-Wide Collation of the Plasmodium falciparum WDR Protein Superfamily Reveals Malarial Parasite-Specific Features
2015 · Priyanka Chahar, Manjeri Kaushik, et al. · PLoS ONE · 13
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Cys-Gly specific dipeptidase Dug1p from S. cerevisiae binds promiscuously to di-, tri-, and tetra-peptides: Peptide–protein interaction, homology modeling, and activity studies reveal a latent promiscuity in substrate recognition☆
2010 · Hardeep Kaur, Manish Datt, et al. · Biochimie · 13
Correction: Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
2016 · Rajnee Kanwal, Manish Datt, et al. · PLoS ONE · 12
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Replacement of the active surface of a thermophile protein by that of a homologous mesophile protein through structure-guided ‘protein surface grafting’
2008 · Divya Kapoor, Vijay Kumar, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 11
Identification through Combinatorial Random and Rational Mutagenesis of a Substrate-interacting Exosite in the γ Domain of Streptokinase
2010 · Suman Yadav, Rachna Aneja, et al. · Journal of Biological Chemistry · 10
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Cloning and characterization of thermotolerant xylitol dehydrogenases from yeast Pichia angusta
2010 · Dipanwita Biswas, Manish Datt, et al. · Applied Microbiology and Biotechnology · 10
In silico assessment of natural products and approved drugs as potential inhibitory scaffolds targeting aminoacyl-tRNA synthetases from Plasmodium
2020 · Ketki Doshi, Niyati Pandya, et al. · 3 Biotech · 8
Redox-dependent stability of the γ-glutamylcysteine synthetase enzyme of Escherichia coli: a novel means of redox regulation
2012 · Shailesh Kumar, Neha Kasturia, et al. · Biochemical Journal · 8
Three Consecutive Arginines Are Important for the Mycobacterial Peptide Deformylase Enzyme Activity
2008 · Rahul Saxena, Pavitra Kanudia, et al. · Journal of Biological Chemistry · 7
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Works count: 37
Citation count: 784
H-index: 14
I10-index: 22
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