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Tomas Björklund

Observed names: Björklund, Tomas, T Björklund, T. Björklund, Tomas Bjorklund
Institution: Lund University
ORCID: 0000-0001-7968-0034
Observed ORCID: 0000-0001-7968-0034
OpenAlex ID: A5031631254
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
2014 · Staffan Holmqvist, Oldriska Chutna, et al. · Acta Neuropathologica · 973
A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System
2010 · Mari Iwamoto, Tomas Björklund, et al. · Chemistry & Biology · 399
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain
2007 · Andisheh Eslamboli, Marina Romero-Ramos, et al. · Brain · 234
A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism
2019 · Marcus Davidsson, Gang Wang, et al. · Proceedings of the National Academy of Sciences · 147
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Applications of Lentiviral Vectors for Biology and Gene Therapy of Neurological Disorders
2008 · Cecilia Lundberg, Tomas Bjorklund, et al. · Current Gene Therapy · 133
A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency
2018 · Julie Tordo, Claire O’Leary, et al. · Brain · 113
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Mutant Huntingtin Causes Metabolic Imbalance by Disruption of Hypothalamic Neurocircuits
2011 · Sofia Hult, Rana Soylu, et al. · Cell Metabolism · 110
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Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level
2016 · Trine A. Kristiansen, Elin Jaensson Gyllenbäck, et al. · Immunity · 98
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Differential Transduction Following Basal Ganglia Administration of Distinct Pseudotyped AAV Capsid Serotypes in Nonhuman Primates
2009 · Hemraj B Dodiya, Tomas Bjorklund, et al. · Molecular Therapy · 89
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AAV Production Everywhere: A Simple, Fast, and Reliable Protocol for In‐house AAV Vector Production Based on Chloroform Extraction
2020 · Matilde Negrini, Gang Wang, et al. · Current Protocols in Neuroscience · 84
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A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP
2013 · Christian Hansen, Tomas Björklund, et al. · Neurobiology of Disease · 73
Dose Optimization for Long-term rAAV-mediated RNA Interference in the Nigrostriatal Projection Neurons
2009 · Ayse Ulusoy, Gurdal Sahin, et al. · Molecular Therapy · 73
DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
2016 · Patrick Aldrin-Kirk, Andreas Heuer, et al. · Neuron · 65
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Gene therapy for Parkinson's disease
2010 · Tomas Bjorklund, Jeffrey H. Kordower · Movement Disorders · 57
Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons
2012 · Ayse Ulusoy, Tomas Björklund, et al. · Neurobiology of Disease · 56
Morphometric and Psychometric Comparisons between Non-Substance-Abusing Patients with Posttraumatic Stress Disorder and Normal Controls
2006 · Reza Emdad, David Bonekamp, et al. · Psychotherapy and Psychosomatics · 56
Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum
2017 · Patrick Aldrin-Kirk, Andreas Heuer, et al. · Neurobiology of Disease · 48
Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson’s disease
2010 · Tomas Björklund, Thomas Carlsson, et al. · Brain · 48
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Restoration of the Striatal Dopamine Synthesis for Parkinsons Disease:Viral Vector-Mediated Enzyme Replacement Strategy
2007 · Thomas Carlsson, Tomas Bjorklund, et al. · Current Gene Therapy · 48
Gene Therapy for Dopamine Replacement in Parkinson´s Disease
2009 · Anders Björklund, Tomas Björklund, et al. · Science Translational Medicine · 42
In vivo gene delivery for development of mammalian models for Parkinson's disease
2007 · Ayse Ulusoy, Tomas Bjorklund, et al. · Experimental Neurology · 42
Scientific rationale for the development of gene therapy strategies for Parkinson's disease
2009 · Tomas Björklund, Deniz Kirik · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 39
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Design of a Single AAV Vector for Coexpression of TH and GCH1 to Establish Continuous DOPA Synthesis in a Rat Model of Parkinson's Disease
2012 · Erik Cederfjäll, Gurdal Sahin, et al. · Molecular Therapy · 37
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Seeding of protein aggregation causes cognitive impairment in rat model of cortical synucleinopathy
2019 · Elena Espa, Erik K.H. Clemensson, et al. · Movement Disorders · 35
Positron Emission Tomography Imaging Demonstrates Correlation between Behavioral Recovery and Correction of Dopamine Neurotransmission after Gene Therapy
2009 · Ludovic Leriche, Tomas Björklund, et al. · Journal of Neuroscience · 34
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Works count: 66
Citation count: 3,500
H-index: 27
I10-index: 41
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