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H. Akiko Popiel

Observed names: H A Popiel, H Akiko Popiel, H. Popiel, H.A. Popiel, Helena A. Popiel, Helena Akiko Popiel, Popiel, Helena Akiko
ORCID: 0000-0001-5797-2773
Observed ORCID: 0000-0001-5797-2773
OpenAlex ID: A5031745118
A toxic monomeric conformer of the polyglutamine protein
2007 · Yoshitaka Nagai, Takashi Inui, et al. · Nature Structural & Molecular Biology · 333
Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level
2015 · Toshihide Takeuchi, Mari Suzuki, et al. · Proceedings of the National Academy of Sciences · 207
Heat Shock Transcription Factor 1-activating Compounds Suppress Polyglutamine-induced Neurodegeneration through Induction of Multiple Molecular Chaperones
2008 · Nobuhiro Fujikake, Yoshitaka Nagai, et al. · Journal of Biological Chemistry · 199
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Detection of Polyglutamine Protein Oligomers in Cells by Fluorescence Correlation Spectroscopy
2007 · Yasuo Takahashi, Yuma Okamoto, et al. · Journal of Biological Chemistry · 97
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Alternative splicing regulates the transcriptional activity of Drosophila heat shock transcription factor in response to heat/cold stress
2005 · Nobuhiro Fujikake, Yoshitaka Nagai, et al. · FEBS Letters · 87
Transgenic Monkey Model of the Polyglutamine Diseases Recapitulating Progressive Neurological Symptoms
2017 · Ikuo Tomioka, Hidetoshi Ishibashi, et al. · eNeuro · 86
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Induction of Molecular Chaperones as a Therapeutic Strategy for the Polyglutamine Diseases
2010 · Yoshitaka Nagai, Nobuhiro Fujikake, et al. · Current Pharmaceutical Biotechnology · 74
p62 Plays a Protective Role in the Autophagic Degradation of Polyglutamine Protein Oligomers in Polyglutamine Disease Model Flies
2014 · Yuji Saitoh, Nobuhiro Fujikake, et al. · Journal of Biological Chemistry · 61
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Supplemental Treatment for Huntington’s Disease with miR-132 that Is Deficient in Huntington’s Disease Brain
2018 · Masashi Fukuoka, Masaki Takahashi, et al. · Molecular Therapy — Nucleic Acids · 58
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Protein Transduction Domain-mediated Delivery of QBP1 Suppresses Polyglutamine-induced Neurodegeneration In Vivo
2007 · H Akiko Popiel, Yoshitaka Nagai, et al. · Molecular Therapy · 58
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Conformational Changes and Aggregation of Expanded Polyglutamine Proteins as Therapeutic Targets of the Polyglutamine Diseases: Exposed β-Sheet Hypothesis
2008 · Yoshitaka Nagai, H. Popiel · Current Pharmaceutical Design · 57
Delivery of the aggregate inhibitor peptide QBP1 into the mouse brain using PTDs and its therapeutic effect on polyglutamine disease mice
2008 · H. Akiko Popiel, Yoshitaka Nagai, et al. · Neuroscience Letters · 49
Hsp40 Gene Therapy Exerts Therapeutic Effects on Polyglutamine Disease Mice via a Non-Cell Autonomous Mechanism
2012 · H. Akiko Popiel, Toshihide Takeuchi, et al. · PLoS ONE · 43
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Inhibition of Protein Misfolding/Aggregation Using Polyglutamine Binding Peptide QBP1 as a Therapy for the Polyglutamine Diseases
2013 · H. Akiko Popiel, Toshihide Takeuchi, et al. · Neurotherapeutics · 37
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Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation
2020 · Eiko N Minakawa, Helena Akiko Popiel, et al. · Brain · 36
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The Aggregation Inhibitor Peptide QBP1 as a Therapeutic Molecule for the Polyglutamine Neurodegenerative Diseases
2011 · H. Akiko Popiel, James R. Burke, et al. · Journal of Amino Acids · 33
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Disruption of the toxic conformation of the expanded polyglutamine stretch leads to suppression of aggregate formation and cytotoxicity
2004 · Helena A. Popiel, Yoshitaka Nagai, et al. · Biochemical and Biophysical Research Communications · 26
Development, validity, and reliability of the Japanese version of the 7C of vaccination readiness scale
2022 · Masaki Machida, Takako Kojima, et al. · American Journal of Infection Control · 25
Structure–activity relationship study on polyglutamine binding peptide QBP1
2008 · Kenji Tomita, H. Akiko Popiel, et al. · Bioorganic & Medicinal Chemistry · 24
Surface plasmon resonance characterization of specific binding of polyglutamine aggregation inhibitors to the expanded polyglutamine stretch
2008 · Yuma Okamoto, Yoshitaka Nagai, et al. · Biochemical and Biophysical Research Communications · 22
Using Guidelines to Improve Scientific Writing: Tips on Use of Correct Verb Tenses for Non-Native English-Speaking Researchers
2022 · Takako Kojima, Helena A. Popiel · Journal of Korean Medical Science · 12
Peptide-Based Therapeutic Approaches for Treatment of the Polyglutamine Diseases
2014 · Toshihide Takeuchi, H. Popiel, et al. · Current Medicinal Chemistry · 8
Proper Scholarly Writing for Non-Native English-Speaking Authors: Choosing Active and Passive Voice, Rewording, and Refining Texts
2022 · Takako Kojima, Helena A. Popiel · Journal of Korean Medical Science · 4
Strategies on Reducing Wordiness to Enhance Readability in Academic Writing
2024 · Takako Kojima, Helena A. Popiel · Journal of Korean Medical Science · 3
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Effective Use of Hedging in Scientific Manuscripts: Advice to Non-Native English-Speaking Researchers
2023 · Takako Kojima, Helena A. Popiel · Journal of Korean Medical Science · 3
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Works count: 39
Citation count: 1,653
H-index: 20
I10-index: 21
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