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Pei Xin Lim
Observed names:
P X Lim,
Pei-Xin Lim
Institution:
Ideaya Biosciences (United States)
Observed institutions:
Memorial Sloan Kettering Cancer Center,
Cornell University,
Purdue University West Lafayette,
Ideaya Biosciences (United States)
ORCID:
0000-0001-5742-3539
Observed ORCID:
0000-0001-5742-3539
OpenAlex ID:
A5031782217
Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer
2017
·
Chun-Chin Chen
, Weiran Feng
, et al.
·
Annual Review of Cancer Biology
·
326
PDF
BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
2024
·
Pei Xin Lim
, Mahdia Zaman
, et al.
·
Molecular Cell
·
85
PDF
Conditional Inactivation of the DNA Damage Response Gene Hus1 in Mouse Testis Reveals Separable Roles for Components of the RAD9-RAD1-HUS1 Complex in Meiotic Chromosome Maintenance
2013
·
Amy M. Lyndaker
, Pei Xin Lim
, et al.
·
PLoS Genetics
·
60
PDF
Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
2021
·
Rohit Prakash
, Thomas Sandoval
, et al.
·
Nature Communications
·
49
PDF
Robust homology-directed repair within mouse mammary tissue is not specifically affected by Brca2 mutation
2016
·
Elizabeth M. Kass
, Pei Xin Lim
, et al.
·
Nature Communications
·
45
PDF
Rapid interrogation of cancer cell of origin through CRISPR editing
2021
·
Weiran Feng
, Zhen Cao
, et al.
·
Proceedings of the National Academy of Sciences
·
24
Genome Protection by the 9-1-1 Complex Subunit HUS1 Requires Clamp Formation, DNA Contacts, and ATR Signaling-independent Effector Functions
2015
·
Pei Xin Lim
, Darshil R. Patel
, et al.
·
Journal of Biological Chemistry
·
17
BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks
2024
·
Daniela Georgieva
, Ning Wang
, et al.
·
Cell Reports
·
14
HUS1 regulates in vivo responses to genotoxic chemotherapies
2015
·
G Balmus
, P X Lim
, et al.
·
Oncogene
·
11
Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system
2010
·
Shreya Datta
, Megan E. Bucks
, et al.
·
Bioorganic & Medicinal Chemistry
·
9
Abstract 232: IDE034, A bispecific antibody-drug conjugate co-targeting PTK7 and B7-H3, exhibits avidity-driven selectivity and enhanced antitumor activity versus mono-specific ADCs.
2026
·
Diana M Munoz Delgado
, Ying Zhu
, et al.
·
Cancer Research
·
1
Abstract 2899: PARG inhibition provokes a DNA damage-dependent innate immune reaction that enhances ICI-driven anti-tumor immunity
2025
·
Reeja Maskey
, Megan Conway
, et al.
·
Cancer Research
·
1
Abstract A27: Assessing somatic tumor-associated RAD51 mutations and screening for novel dominant-interfering RAD51 proteins
2017
·
Pei Xin Lim
, Jeanette Sutherland
, et al.
·
Molecular Cancer Research
·
1
Abstract IA014: BRCA2 promotes genomic integrity and therapy resistance primarily through its role in homology-directed repair
2024
·
Pei Xin Lim
, Maria Jasin
·
Cancer Research
Mechanistic Functions Of The 9-1-1 Complex Subunit Hus1 In The Maintenance Of Genomic Integrity
2015
·
Pei Xin Lim
·
eCommons (Cornell University)
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Works count:
15
Citation count:
643
H-index:
9
I10-index:
9
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