Author

David A. Copland

Observed names: Copland David, Copland, Dave, Copland, Dave A, Copland, David A, Copland, David A., Copland, David Alexander, D A Copland, D. A. Copland, D. Copland, Dave Copland, David A Copland, David Copland

Institutions: Moorfields Eye Hospital NHS Foundation Trust, National Institute for Health and Care Research, University of Bristol, NIHR Moorfields Biomedical Research Centre, Moorfields Eye Hospital, University College London

Observed institutions: National Health Service, Moorfields Eye Hospital NHS Foundation Trust, Harvard University, National Institute for Health and Care Research, University of Bristol, NIHR Moorfields Biomedical Research Centre, Bristol Eye Hospital, Moorfields Eye Hospital, Wyss Institute for Biologically Inspired Engineering, University College London

ORCID: 0000-0003-4044-4952

Observed ORCID: 0000-0003-4044-4952

OpenAlex ID: A5031815951

Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses

2021 · Ying Kai Chan, Ying Kai Chan, et al. · Science Translational Medicine · 213

Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations

2008 · Emma C. Kerr, Ben J.E. Raveney, et al. · Journal of Autoimmunity · 162

Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration

2021 · Keng Siang Lee, Shuxiao Lin, et al. · Journal of Neuroinflammation · 150

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Monoclonal Antibody-Mediated CD200 Receptor Signaling Suppresses Macrophage Activation and Tissue Damage in Experimental Autoimmune Uveoretinitis

2007 · David A. Copland, Claudia J. Calder, et al. · American Journal Of Pathology · 138

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Homeostatic regulation of T cell trafficking by a B cell–derived peptide is impaired in autoimmune and chronic inflammatory disease

2015 · Myriam Chimen, Helen M McGettrick, et al. · Nature Medicine · 119

Myeloid Cells Expressing VEGF and Arginase-1 Following Uptake of Damaged Retinal Pigment Epithelium Suggests Potential Mechanism That Drives the Onset of Choroidal Angiogenesis in Mice

2013 · Jian Liu, David A. Copland, et al. · PLoS ONE · 108

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The dynamics of leukocyte infiltration in experimental autoimmune uveoretinitis

2008 · Emma C. Kerr, David A. Copland, et al. · Progress in Retinal and Eye Research · 107

Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9

2020 · Jiahui Wu, Oliver H. Bell, et al. · Molecular Therapy · 96

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Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis

2016 · Jian Liu, David A. Copland, et al. · Scientific Reports · 87

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Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis

2009 · D A Copland, K Hussain, et al. · Clinical & Experimental Immunology · 79

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The Clinical Time-Course of Experimental Autoimmune Uveoretinitis Using Topical Endoscopic Fundal Imaging with Histologic and Cellular Infiltrate Correlation

2008 · David A. Copland, Michael S. Wertheim, et al. · Investigative Ophthalmology & Visual Science · 70

A Perspective of AMD Through the Eyes of Immunology

2018 · David A. Copland, Sofia Theodoropoulou, et al. · Investigative Ophthalmology & Visual Science · 66

Interleukin‐33 regulates tissue remodelling and inhibits angiogenesis in the eye

2016 · Sofia Theodoropoulou, David A Copland, et al. · The Journal of Pathology · 62

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Persistent Inflammation Subverts Thrombospondin-1–Induced Regulation of Retinal Angiogenesis and Is Driven by CCR2 Ligation

2011 · Mei Chen, David A. Copland, et al. · American Journal Of Pathology · 60

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Glucocorticoid-resistant Th17 cells are selectively attenuated by cyclosporine A

2015 · Lauren P. Schewitz-Bowers, Philippa J. P. Lait, et al. · Proceedings of the National Academy of Sciences · 58

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TNFR1-Dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis

2009 · Ben J E Raveney, David A Copland, et al. · The Journal of Immunology · 53

Therapeutic Dosing of Fingolimod (FTY720) Prevents Cell Infiltration, Rapidly Suppresses Ocular Inflammation, and Maintains the Blood-Ocular Barrier

2011 · David A. Copland, Jian Liu, et al. · American Journal Of Pathology · 50

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Tissue-Resident Exhausted Effector Memory CD8+ T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis

2014 · Joanne Boldison, Colin J Chu, et al. · The Journal of Immunology · 49

Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood–Retinal Barrier Integrity In Vitro

2019 · Marina Mesquida, Faye Drawnel, et al. · Translational Vision Science & Technology · 47

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IL-4 Regulates Specific Arg-1+ Macrophage sFlt-1–Mediated Inhibition of Angiogenesis

2015 · Wei-Kang Wu, Anastasios Georgiadis, et al. · American Journal Of Pathology · 44

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CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization

2013 · Shintaro Horie, Scott J. Robbie, et al. · Scientific Reports · 41

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Fingolimod (FTY720) as an Acute Rescue Therapy for Intraocular Inflammatory Disease

2008 · B. J. E. Raveney, D. A. Copland, et al. · Archives of Ophthalmology · 39

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Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes

2024 · Monica Gamez, Hesham E. Elhegni, et al. · Cardiovascular Diabetology · 33

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Environmental conditioning in the control of macrophage thrombospondin-1 production

2012 · Jezrom B. Fordham, Jing Hua, et al. · Scientific Reports · 33

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Tumour necrosis factor-mediated macrophage activation in the target organ is critical for clinical manifestation of uveitis

2012 · T K Khera, D A Copland, et al. · Clinical & Experimental Immunology · 32

Works count: 120

Citation count: 2,455

H-index: 26

I10-index: 46