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Sahar A. Saddoughi

Observed names: S. A Saddoughi, S. Saddoughi, S.-A.-S. Saddoughi, S.A. Saddoughi, SAHAR A SADDOUGHI, SAHAR SADDOUGHI, Sahar A. Saddoughi, Sahar A Saddoughi, Sahar S. Saddoughi, Sahar Saddoughi, Sahar-Al-Sadat Saddoughi
Institution: Mayo Clinic
Observed institutions: University Health Network, Mayo Clinic, Medical University of South Carolina, University of California, Los Angeles, Toronto General Hospital, MUSC Hollings Cancer Center, McGill University
ORCID: 0000-0002-5609-1488
Observed ORCID: 0000-0002-5609-1488
OpenAlex ID: A5061457621
Sphingolipids and Cancer: Ceramide and Sphingosine-1-Phosphate in the Regulation of Cell Death and Drug Resistance
2010 · Suriyan Ponnusamy, Marisa Meyers-Needham, et al. · Future Oncology · 313
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis
2012 · Sahar A. Saddoughi, Salih Gencer, et al. · EMBO Molecular Medicine · 265
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Roles of Bioactive Sphingolipids in Cancer Biology and Therapeutics
2008 · Sahar A. Saddoughi, Pengfei Song, et al. · Sub-cellular biochemistry/Subcellular biochemistry · 244
PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells
2013 · Paolo Neviani, Jason G. Harb, et al. · Journal of Clinical Investigation · 221
Direct interaction between the inhibitor 2 and ceramide via sphingolipid‐protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
2008 · Archana Mukhopadhyay, Sahar A. Saddoughi, et al. · The FASEB Journal · 208
Diverse Functions of Ceramide in Cancer Cell Death and Proliferation
2013 · Sahar A. Saddoughi, Besim Ogretmen · Advances in cancer research · 176
Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+ and ER/Golgi Membrane Network
2011 · Can E. Senkal, Suriyan Ponnusamy, et al. · Journal of Biological Chemistry · 138
Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A
2011 · Arelis Salas, Suriyan Ponnusamy, et al. · Blood · 120
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Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies
2013 · Joshua J. Oaks, Ramasamy Santhanam, et al. · Blood · 110
Results of a Phase II Trial of Gemcitabine Plus Doxorubicin in Patients with Recurrent Head and Neck Cancers: Serum C18-Ceramide as a Novel Biomarker for Monitoring Response
2011 · Sahar A. Saddoughi, Elizabeth Garrett-Mayer, et al. · Clinical Cancer Research · 68
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National Trends in the Epidemiology of Malignant Pleural Mesothelioma: A National Cancer Data Base Study
2017 · Sahar A. Saddoughi, Zaid M. Abdelsattar, et al. · The Annals of Thoracic Surgery · 67
Comparison of Laparoscopic Versus Open Surgical Management of Morgagni Hernia
2018 · Michael C. Young, Sahar A. Saddoughi, et al. · The Annals of Thoracic Surgery · 56
Survival After Surgical Resection of Stage IV Esophageal Cancer
2016 · Sahar A. Saddoughi, J. Matthew Reinersman, et al. · The Annals of Thoracic Surgery · 48
Off-Target Function of the Sonic Hedgehog Inhibitor Cyclopamine in Mediating Apoptosis via Nitric Oxide–Dependent Neutral Sphingomyelinase 2/Ceramide Induction
2012 · Marisa Meyers-Needham, Jocelyn A. Lewis, et al. · Molecular Cancer Therapeutics · 45
The 2024 American Association for Thoracic Surgery expert consensus document: Current standards in donor lung procurement and preservation
2025 · Jasleen Kukreja, Jose Luis Campo-Canaveral de la Cruz, et al. · Journal of Thoracic and Cardiovascular Surgery · 32
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Esophagectomy Enhanced Recovery After Surgery Initiative Results in Improved Outcomes
2023 · Charles R. Sims, Mohamad K. Abou Chaar, et al. · The Annals of Thoracic Surgery · 20
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Determinants of Long-term Survival Decades After Esophagectomy for Esophageal Cancer
2023 · Mohamad K. Abou Chaar, Anny Godin, et al. · The Annals of Thoracic Surgery · 18
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Early national trends of lung allograft use during donation after circulatory death heart procurement in the United States
2023 · Kukbin Choi, Cristiano Spadaccio, et al. · JTCVS Open · 17
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Cumulative epinephrine dose during cardiac arrest and neurologic outcome after extracorporeal cardiopulmonary resuscitation
2024 · Samuel I. Garcia, Troy G. Seelhammer, et al. · The American Journal of Emergency Medicine · 16
Risk Factors for Early Fungal Disease in Solid Organ Transplant Recipients: A Systematic Review and Meta-analysis
2023 · Kelly M. Pennington, Max J. Martin, et al. · Transplantation · 16
Short and long-term outcomes of lung transplantation from brain death vs. circulatory death donors: A meta-analysis of comparative studies
2025 · Cristiano Spadaccio, Antonio Salsano, et al. · The Journal of Heart and Lung Transplantation · 14
Expanding the Lung Donor Pool
2023 · Sahar A. Saddoughi, Marcelo Cypel · Clinics in Chest Medicine · 14
Impact of normothermic regional perfusion during DCD recovery on lung allograft function: A preclinical study
2023 · Rafaela V.P. Ribeiro, Frank A. Reynolds, et al. · JHLT Open · 12
Surgical Resection of Rare Esophageal Cancers
2015 · Sahar A. Saddoughi, Jim Taswell, et al. · The Annals of Thoracic Surgery · 12
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Impact of lymph node evaluation standard in patients undergoing lung resection for clinical stage IA pulmonary adenocarcinoma and squamous cell carcinoma
2024 · Raffaele Rocco, Brandon S. Hendriksen, et al. · Journal of Thoracic Disease · 11
Works count: 133
Citation count: 2,459
H-index: 17
I10-index: 28
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