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Peter Sjö
Observed names:
P. Sjö,
Peter Sjo,
Peter Sjö,
Sjö, Peter,
Sjö, Peter
Institution:
Drugs for Neglected Diseases Initiative
Observed institutions:
AstraZeneca (United Kingdom),
Goethe University Frankfurt,
Scripps Research Institute,
Drugs for Neglected Diseases Initiative,
University of Oslo,
AstraZeneca (Sweden),
Medicines for Malaria Venture,
Massachusetts Institute of Technology
show all 8
ORCID:
0000-0002-6768-0536
Observed ORCID:
0000-0002-6768-0536
OpenAlex ID:
A5032037097
Works
55
Awards
1
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
2023
·
Melissa L. Boby
, Daren Fearon
, et al.
·
Science
·
252
Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease
2023
·
Gabriela Dias Noske
, Ellen de Souza Silva
, et al.
·
Journal of Biological Chemistry
·
131
PDF
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern
2022
·
Rana Abdelnabi
, Caroline S. Foo
, et al.
·
Nature Communications
·
123
PDF
Facing the escalating burden of dengue: Challenges and perspectives
2023
·
Gathsaurie Neelika Malavige
, Peter Sjö
, et al.
·
PLOS Global Public Health
·
91
PDF
Explanation for Main Features of Structure–Genotoxicity Relationships of Aromatic Amines by Theoretical Studies of Their Activation Pathways in CYP1A2
2011
·
Igor Shamovsky
, Lena Ripa
, et al.
·
Journal of the American Chemical Society
·
84
Asymmetric dihydroxylation of enynes
1992
·
Kyu-Sung Jeong
, Peter Sjö
, et al.
·
Tetrahedron Letters
·
71
Mining Natural Products for Macrocycles to Drug Difficult Targets
2020
·
Fabio Begnini
, Vasanthanathan Poongavanam
, et al.
·
Journal of Medicinal Chemistry
·
50
PDF
Importance of Binding Site Hydration and Flexibility Revealed When Optimizing a Macrocyclic Inhibitor of the Keap1–Nrf2 Protein–Protein Interaction
2022
·
Fabio Begnini
, Stefan Geschwindner
, et al.
·
Journal of Medicinal Chemistry
·
48
Toward the Design of Molecular Chameleons: Flexible Shielding of an Amide Bond Enhances Macrocycle Cell Permeability
2018
·
Mohit Tyagi
, Vasanthanathan Poongavanam
, et al.
·
Organic Letters
·
41
A Computational Community Blind Challenge on Pan-Coronavirus Drug Discovery Data
2026
·
Hugo MacDermott-Opeskin
, Jenke Scheen
, et al.
·
Journal of Chemical Information and Modeling
·
32
PDF
Neutrophil Elastase Inhibitors: Recent Advances In The Development Of Mechanism-Based And Nonelectrophilic Inhibitors
2012
·
Peter Sjö
·
Future Medicinal Chemistry
·
32
Turning high-throughput structural biology into predictive inhibitor design
2023
·
Kadi L. Saar
, William McCorkindale
, et al.
·
Proceedings of the National Academy of Sciences
·
29
Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model
2022
·
David Péricat
, Stephen Adonai Leon-Icaza
, et al.
·
International Journal of Molecular Sciences
·
26
PDF
Toward Consensus on Correct Interpretation of Protein Binding in Plasma and Other Biological Matrices for COVID‐19 Therapeutic Development
2020
·
Marta Boffito
, David J. Back
, et al.
·
Clinical Pharmacology & Therapeutics
·
26
PDF
Theoretical Studies of Chemical Reactivity of Metabolically Activated Forms of Aromatic Amines toward DNA
2012
·
Igor Shamovsky
, Lena Ripa
, et al.
·
Chemical Research in Toxicology
·
26
High-throughput screening of small-molecules libraries identified antibacterials against clinically relevant multidrug-resistant A. baumannii and K. pneumoniae
2024
·
Benjamin Blasco
, Soojin Jang
, et al.
·
EBioMedicine
·
25
Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2
2022
·
Jean-Sélim Driouich
, Maxime Cochin
, et al.
·
EBioMedicine
·
21
PDF
Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants
2017
·
Cristina N. Alexandru-Crivac
, Christian Umeobika
, et al.
·
Chemical Communications
·
21
PDF
Theoretical Studies of the Mechanism of N-Hydroxylation of Primary Aromatic Amines by Cytochrome P450 1A2: Radicaloid or Anionic?
2014
·
Lena Ripa
, Christine Mee
, et al.
·
Chemical Research in Toxicology
·
21
Susceptibility Testing of Medically Important Parasites
2017
·
Abebe Genetu Bayih
, Anjan Debnath
, et al.
·
Clinical Microbiology Reviews
·
14
PDF
Core outcome measurement set for clinical trials in dengue: an international Delphi consensus study (DEN-CORE)
2025
·
Sophie Yacoub
, Anastasia Demidova
, et al.
·
The Lancet Infectious Diseases
·
13
PDF
Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2
2022
·
Benoît Laleu
, Kelly Rubiano
, et al.
·
ChemMedChem
·
12
PDF
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19
2022
·
Frauke Assmus
, Jean-Sélim Driouich
, et al.
·
Microorganisms
·
11
PDF
Theoretical studies of the second step of the nitric oxide synthase reaction: Electron tunneling prevents uncoupling
2018
·
Igor Shamovsky
, Graham Belfield
, et al.
·
Journal of Inorganic Biochemistry
·
11
4-Anilino-6-phenyl-quinoline inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK2)
2010
·
Henric Olsson
, Peter Sjö
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
11
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Works count:
55
Citation count:
1,292
H-index:
19
I10-index:
26
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