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Kanchan Garai
Observed names:
Garai, Kanchan,
K. Garai
Institution:
Tata Institute of Fundamental Research
Observed institutions:
Tata Institute of Fundamental Research,
University of Pittsburgh,
Washington University in St. Louis,
TIFR Centre for Interdisciplinary Sciences,
Hope Center for Neurological Disorders
ORCID:
0000-0003-3753-7699
Observed ORCID:
0000-0003-3753-7699
OpenAlex ID:
A5033062872
ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions
2013
·
Philip B. Verghese
, Joseph M. Castellano
, et al.
·
Proceedings of the National Academy of Sciences
·
555
PDF
Measuring Size Distribution in Highly Heterogeneous Systems with Fluorescence Correlation Spectroscopy
2003
·
Parijat Sengupta
, K. Garai
, et al.
·
Biophysical Journal
·
218
PDF
Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation
2013
·
Scott L. Crick
, Kiersten M. Ruff
, et al.
·
Proceedings of the National Academy of Sciences
·
213
PDF
The Amyloid β Peptide (Aβ 1 - 40 ) Is Thermodynamically Soluble at Physiological Concentrations
2003
·
Parijat Sengupta
, K. Garai
, et al.
·
Biochemistry
·
167
The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation
2014
·
Kanchan Garai
, Philip B. Verghese
, et al.
·
Biochemistry
·
144
Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ
2013
·
Kanchan Garai
, Carl Frieden
·
Proceedings of the National Academy of Sciences
·
138
Structural differences between apoE3 and apoE4 may be useful in developing therapeutic agents for Alzheimer’s disease
2012
·
Carl Frieden
, Kanchan Garai
·
Proceedings of the National Academy of Sciences
·
132
Zinc Lowers Amyloid-β Toxicity by Selectively Precipitating Aggregation Intermediates
2007
·
K. Garai
, B. Sahoo
, et al.
·
Biochemistry
·
110
Quantitative Assessments of the Distinct Contributions of Polypeptide Backbone Amides versus Side Chain Groups to Chain Expansion via Chemical Denaturation
2015
·
Alex S. Holehouse
, Kanchan Garai
, et al.
·
Journal of the American Chemical Society
·
109
Lipopolysaccharide from Gut Microbiota Modulates α-Synuclein Aggregation and Alters Its Biological Function
2019
·
Dipita Bhattacharyya
, Ganesh M. Mohite
, et al.
·
ACS Chemical Neuroscience
·
108
Selective destabilization of soluble amyloid β oligomers by divalent metal ions
2006
·
K. Garai
, P. Sengupta
, et al.
·
Biochemical and Biophysical Research Communications
·
102
Hydrogen/Deuterium Exchange and Electron-Transfer Dissociation Mass Spectrometry Determine the Interface and Dynamics of Apolipoprotein E Oligomerization
2011
·
Richard Y-C. Huang
, Kanchan Garai
, et al.
·
Biochemistry
·
100
Mechanism of Secondary Nucleation at the Single Fibril Level from Direct Observations of Aβ42 Aggregation
2021
·
Manuela R. Zimmermann
, Subhas C. Bera
, et al.
·
Journal of the American Chemical Society
·
78
Mass Spectrometry-Based Protein Footprinting Characterizes the Structures of Oligomeric Apolipoprotein E2, E3, and E4
2011
·
Brian Gau
, Kanchan Garai
, et al.
·
Biochemistry
·
74
The Association−Dissociation Behavior of the ApoE Proteins: Kinetic and Equilibrium Studies
2010
·
Kanchan Garai
, Carl Frieden
·
Biochemistry
·
70
Quasihomogeneous nucleation of amyloid beta yields numerical bounds for the critical radius, the surface tension, and the free energy barrier for nucleus formation
2008
·
K. Garai
, B. Sahoo
, et al.
·
The Journal of Chemical Physics
·
62
Dissociation of Apolipoprotein E Oligomers to Monomer Is Required for High-Affinity Binding to Phospholipid Vesicles
2011
·
Kanchan Garai
, Berevan Baban
, et al.
·
Biochemistry
·
57
Probing transient non-native states in amyloid beta fiber elongation by NMR
2019
·
Jeffrey R. Brender
, Anirban Ghosh
, et al.
·
Chemical Communications
·
53
Detecting Amyloid-β Aggregation with Fiber-Based Fluorescence Correlation Spectroscopy
2007
·
Kanchan Garai
, Ruchi Sureka
, et al.
·
Biophysical Journal
·
47
Inhibition of amyloid beta fibril formation by monomeric human transthyretin
2018
·
Kanchan Garai
, Ammon E. Posey
, et al.
·
Protein Science
·
44
PDF
High‐affinity multivalent interactions between apolipoprotein E and the oligomers of amyloid‐β
2019
·
Shamasree Ghosh
, Timir Baran Sil
, et al.
·
FEBS Journal
·
38
Concerning the structure of apoE
2013
·
Carl Frieden
, Kanchan Garai
·
Protein Science
·
38
PDF
Expression and purification of amyloid-β peptides from Escherichia coli
2009
·
Kanchan Garai
, Scott L. Crick
, et al.
·
Protein Expression and Purification
·
35
Lipid-induced condensate formation from the Alzheimer’s Aβ peptide triggers amyloid aggregation
2025
·
Greta Šneiderienė
, Alicia González Díaz
, et al.
·
Proceedings of the National Academy of Sciences
·
29
PDF
Self-Association and Stability of the ApoE Isoforms at Low pH: Implications for ApoE–Lipid Interactions
2011
·
Kanchan Garai
, Berevan Baban
, et al.
·
Biochemistry
·
27
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Works count:
80
Citation count:
2,981
H-index:
25
I10-index:
35
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