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Author

Huiwen Che

Observed names: Che, Huiwen, H. Che
Institution: KU Leuven
Observed institutions: Uppsala University, Chinese University of Hong Kong, Science for Life Laboratory, Prince of Wales Hospital, Aligning Science Across Parkinson's, KU Leuven
ORCID: 0000-0002-3651-069X
Observed ORCID: 0000-0002-3651-069X
OpenAlex ID: A5033501843
SweGen: a whole-genome data resource of genetic variability in a cross-section of the Swedish population
2017 · Adam Ameur, Johan Dahlberg, et al. · European Journal of Human Genetics · 209
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Cell-free DNA methylome analysis for early preeclampsia prediction
2023 · Marie De Borre, Huiwen Che, et al. · Nature Medicine · 89
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Comprehensive genome-wide analysis of routine non-invasive test data allows cancer prediction: A single-center retrospective analysis of over 85,000 pregnancies
2021 · Liesbeth Lenaerts, Nathalie Brison, et al. · EClinicalMedicine · 83
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De Novo Assembly of Two Swedish Genomes Reveals Missing Segments from the Human GRCh38 Reference and Improves Variant Calling of Population-Scale Sequencing Data
2018 · Adam Ameur, Huiwen Che, et al. · Genes · 58
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Genomewide copy number alteration screening of circulating plasma DNA: potential for the detection of incipient tumors
2018 · L. Lenaerts, P. Vandenberghe, et al. · Annals of Oncology · 53
Benchmarking of methods for DNA methylome deconvolution
2024 · Kobe De Ridder, Huiwen Che, et al. · Nature Communications · 37
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Noninvasive prenatal diagnosis by genome-wide haplotyping of cell-free plasma DNA
2020 · Huiwen Che, Darine Villela, et al. · Genetics in Medicine · 34
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Non‐invasive prenatal testing suggesting a maternal malignancy: What do we tell the prospective parents in Belgium?
2021 · Lore Lannoo, Liesbeth Lenaerts, et al. · Prenatal Diagnosis · 32
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Pregnant women with confirmed neoplasms should not have noninvasive prenatal testing
2019 · Liesbeth Lenaerts, Kristel Van Calsteren, et al. · Prenatal Diagnosis · 28
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Breast Cancer Detection and Treatment Monitoring Using a Noninvasive Prenatal Testing Platform: Utility in Pregnant and Nonpregnant Populations
2020 · Liesbeth Lenaerts, Huiwen Che, et al. · Clinical Chemistry · 21
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Pan-Cancer Detection and Typing by Mining Patterns in Large Genome-Wide Cell-Free DNA Sequencing Datasets
2022 · Huiwen Che, Tatjana Jatsenko, et al. · Clinical Chemistry · 20
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Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma
2024 · Huiwen Che, Peiyong Jiang, et al. · Genome Research · 19
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Machine learning-based detection of immune-mediated diseases from genome-wide cell-free DNA sequencing datasets
2022 · Huiwen Che, Tatjana Jatsenko, et al. · npj Genomic Medicine · 16
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Fetal sex determination in twin pregnancies using non-invasive prenatal testing
2019 · Darine Villela, Huiwen Che, et al. · npj Genomic Medicine · 12
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Expanded knowledge of cell-free DNA biology: potential to broaden the clinical utility
2022 · Huiwen Che, Kate Stanley, et al. · Extracellular Vesicles and Circulating Nucleic Acids · 10
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Longitudinal cell-free DNA methylome and fragmentome profiles in health uncover signatures of cell type and demographic origin
2026 · Mio Aerden, Tatjana Jatsenko, et al. · Genome Medicine · 5
Unbiased genomewide screening of circulating plasma DNA for cancer detection
2018 · L. Lenaerts, N. Brison, et al. · Annals of Oncology · 2
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Cutoff Sample Size Estimation For Survival Data: A Simulation Study
2014 · Huiwen Che · KTH Publication Database DiVA (KTH Royal Institute of Technology) · 2
Mitigating genotype-driven bias improves atlas-scale single-cell DNA methylome profiling
2026 · Xinran Song, Anna Diacofotaki, et al. · bioRxiv (Cold Spring Harbor Laboratory)
More of less: Novel multi-ome profiling of single human neurons
2022 · Huiwen Che, Bernard Thienpont · Cell Genomics
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60 Comprehensive genome-wide analysis of non-invasive test data allows accurate cancer prediction: a retrospective analysis of over 85.000 pregnancies
2021 · L. Lenaerts, N. Brison, et al. · International Journal of Gynecological Cancer
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Genome-wide Profiling and Haplotyping of Cell-free Dna Enabling Combined Non-invasive Prenatal Diagnosis of Inherited Monogenic Diseases and Aneuploidy
2019 · Huiwen Che, Darine Vileila, et al. · Reproductive BioMedicine Online
Evaluation of de novo assembly using PacBio long reads
2016 · Huiwen Che · KTH Publication Database DiVA (KTH Royal Institute of Technology)
Works count: 25
Citation count: 730
H-index: 13
I10-index: 15
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