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Kentaro Iso
Observed names:
Iso, K.,
Iso, Kentaro,
K. Iso
Institution:
University of Dundee
Observed institutions:
Harvard University,
University of Dundee,
Tohoku University,
Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University,
Eisai (Japan)
ORCID:
0000-0001-5417-3642
Observed ORCID:
0000-0001-5417-3642
OpenAlex ID:
A5033556255
Targeted protein degradation via intramolecular bivalent glues
2024
·
Oliver Hsia
, Matthias Hinterndorfer
, et al.
·
Nature
·
230
An Environmentally Friendly Synthetic Method of 1,2-Dihydroisoquinoline Frameworks via Three-Component Reaction with o-Alkynylbenzaldehydes, Primary Amines, and Pronucleophiles
2006
·
Naoki Asao
, Kentaro Iso
, et al.
·
Organic Letters
·
111
A Concise Synthesis of the Pentacyclic Framework of Cortistatins
2008
·
Shuji Yamashita
, Kentaro Iso
, et al.
·
Organic Letters
·
91
Total Synthesis of Cortistatins A and J
2011
·
Shuji Yamashita
, Kentaro Iso
, et al.
·
The Journal of Organic Chemistry
·
77
E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling
2021
·
Kazuhiko Yamada
, Yusaku Hori
, et al.
·
Cancer Research
·
71
A landmark in drug discovery based on complex natural product synthesis
2019
·
Satoshi Kawano
, Ken Ito
, et al.
·
Scientific Reports
·
43
PDF
Unified, Efficient, and Scalable Synthesis of Halichondrins: Zirconium/Nickel‐Mediated One‐Pot Ketone Synthesis as the Final Coupling Reaction
2017
·
Kenzo Yahata
, Ning Ye
, et al.
·
Angewandte Chemie International Edition
·
42
Delivery of a BET protein degrader via a CEACAM6-targeted antibody–drug conjugate inhibits tumour growth in pancreatic cancer models
2024
·
Youya Nakazawa
, Masayuki Miyano
, et al.
·
Nature Communications
·
37
PDF
Efficient and stereoselective installation of isoquinoline: formal total synthesis of cortistatin A
2009
·
Shuji Yamashita
, Kazuki Kitajima
, et al.
·
Tetrahedron Letters
·
35
Dual E3 ligase recruitment by monovalent degraders for tunable SMARCA 2/4 degradation
2026
·
Valentina A. Spiteri
, Dmitri Segal
, et al.
·
Nature Chemical Biology
·
15
Stereocontrolled Synthesis of Left Halves of Halichondrins
2017
·
Kenzo Yahata
, Ning Ye
, et al.
·
The Journal of Organic Chemistry
·
15
Ten-Gram-Scale Total Synthesis of the Anticancer Drug Candidate E7130 to Supply Clinical Trials
2024
·
Yosuke Kaburagi
, Kazunobu Kira
, et al.
·
Organic Letters
·
14
Unified Synthesis of Right Halves of Halichondrins A–C
2017
·
Kenzo Yahata
, Ning Ye
, et al.
·
The Journal of Organic Chemistry
·
14
What Does It Take to Develop Structurally Complex Molecules by Total Synthesis? Rapid Process Development and GMP Manufacturing of E7130 Drug Substance for First-in-Human Clinical Study
2024
·
Takeo Sasaki
, Kenzo Yahata
, et al.
·
Organic Process Research & Development
·
11
A Facile Synthesis of 1,2-Dihydroisoquinolines by Three-Component Reaction
2007
·
Naoki Asao
, Kentaro Iso
, et al.
·
Heterocycles
·
7
Abstract 5177: E7386 : First-in-class orally active CBP/beta-catenin modulator as an anticancer agent
2017
·
Kazuhiko Yamada
, Yusaku Hori
, et al.
·
Cancer Research
·
6
Unified, Efficient, and Scalable Synthesis of Halichondrins: Zirconium/Nickel‐Mediated One‐Pot Ketone Synthesis as the Final Coupling Reaction
2017
·
Kenzo Yahata
, Ning Ye
, et al.
·
Angewandte Chemie
·
5
Synthesis of the Bicyclo[7.3.0]dodecadiyne Core of the Maduropeptin Chromophore
2008
·
Kentaro Iso
, Masayuki Inoue
, et al.
·
Chemistry - An Asian Journal
·
4
Preparation of 1,2-Dihydroisoquinolines by a Three-Component Reaction under Catalyst-Free Conditions
2008
·
Naoki Asao
, Kentaro Iso
, et al.
·
Synthesis
·
3
Induced ubiquitination of the partially disordered estrogen receptor alpha via a 14-3-3 directed molecular glue-PROTAC
2026
·
Carlo J. A. Verhoef
, Charlotte Crowe
, et al.
·
Nature Communications
·
1
Abstract 4179: E7130 derived from total synthesis of halichondrin as a novel tumor-microenvironment ameliorator
2020
·
Satoshi Kawano
, Takanori Abe
, et al.
·
Cancer Research
·
1
An Environmentally Friendly Synthetic Method of 1,2‐Dihydroisoquinoline Frameworks via Three‐Component Reaction with o‐Alkynylbenzaldehydes, Primary Amines, and Pronucleophiles.
2007
·
Naoki Asao
, Kentaro Iso
, et al.
·
ChemInform
·
1
Three-Component Synthesis of 1,2-Dihydroisoquinolines
2006
·
N. Asao
, K. Iso
·
Synfacts
·
1
Data from E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling
2023
·
Kazuhiko Yamada
, Yusaku Hori
, et al.
Supplementary Materials and Methods from E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling
2023
·
Kazuhiko Yamada
, Yusaku Hori
, et al.
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Works count:
34
Citation count:
835
H-index:
13
I10-index:
14
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