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Jack P. K. Bravo

Observed names: Bravo, Jack P.K., J.P.K. Bravo, Jack Bravo, Jack P K Bravo, Jack P.K. Bravo, Jack PK Bravo, Jack Peter Kelly Bravo, P.K. Bravo, Jack
ORCID: 0000-0003-0456-0753
Observed ORCID: 0000-0003-0456-0753
OpenAlex ID: A5033740376
Structural basis for mismatch surveillance by CRISPR–Cas9
2022 · Jack P. K. Bravo, Mu-Sen Liu, et al. · Nature · 284
Remdesivir is a Delayed Translocation Inhibitor of SARS CoV-2 Replication
2020 · Jack P.K. Bravo, Tyler L. Dangerfield, et al. · Molecular Cell · 136
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Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses
2021 · Florian Geiger, Julia Acker, et al. · The EMBO Journal · 121
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RNA targeting unleashes indiscriminate nuclease activity of CRISPR–Cas12a2
2023 · Jack P. K. Bravo, Thomson Hallmark, et al. · Nature · 92
SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation
2021 · Jurre A. Steens, Yifan Zhu, et al. · Nature Communications · 87
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Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9
2024 · Grace N. Hibshman, Jack P. K. Bravo, et al. · Nature Communications · 70
Type III-B CRISPR-Cas cascade of proteolytic cleavages
2024 · Jurre A. Steens, Jack P. K. Bravo, et al. · Science · 54
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Structural basis for broad anti-phage immunity by DISARM
2022 · Jack P. K. Bravo, Cristian Aparicio-Maldonado, et al. · Nature Communications · 45
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Structure of a type IV CRISPR-Cas ribonucleoprotein complex
2021 · Yi Zhou, Jack P.K. Bravo, et al. · iScience · 43
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A single 2′-O-methylation of ribosomal RNA gates assembly of a functional ribosome
2022 · James N. Yelland, Jack P. K. Bravo, et al. · Nature Structural & Molecular Biology · 42
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Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites
2025 · Zhiying Zhang, Thomas C. Todeschini, et al. · Cell · 39
Structural rearrangements allow nucleic acid discrimination by type I-D Cascade
2022 · Evan A. Schwartz, Tess M. McBride, et al. · Nature Communications · 39
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Structural basis for assembly of non-canonical small subunits into type I-C Cascade
2020 · Roisin E. O’Brien, Inês C. Santos, et al. · Nature Communications · 38
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Plasmid targeting and destruction by the DdmDE bacterial defence system
2024 · Jack P. K. Bravo, Delisa A. Ramos, et al. · Nature · 37
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Structural basis of rotavirus RNA chaperone displacement and RNA annealing
2021 · Jack P. K. Bravo, Kira Bartnik, et al. · Proceedings of the National Academy of Sciences · 37
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RNA targeting and cleavage by the type III-Dv CRISPR effector complex
2024 · Evan A. Schwartz, Jack P. K. Bravo, et al. · Nature Communications · 31
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Stability of local secondary structure determines selectivity of viral RNA chaperones
2018 · Jack P K Bravo, Alexander Borodavka, et al. · Nucleic Acids Research · 31
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Lipid droplets as substrates for protein phase separation
2024 · Advika Kamatar, Jack P.K. Bravo, et al. · Biophysical Journal · 26
RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity
2026 · Oleg Dmytrenko, Biao Yuan, et al. · Nature · 21
Engineered PsCas9 enables therapeutic genome editing in mouse liver with lipid nanoparticles
2024 · Dmitrii Degtev, Jack Bravo, et al. · Nature Communications · 21
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DNA targeting by compact Cas9d and its resurrected ancestor
2025 · Rodrigo Fregoso Ocampo, Jack P. K. Bravo, et al. · Nature Communications · 19
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Structural snapshots of R-loop formation by a type I-C CRISPR Cascade
2023 · Roisin E. O’Brien, Jack P.K. Bravo, et al. · Molecular Cell · 16
Constructing next-generation CRISPR–Cas tools from structural blueprints
2022 · Jack PK Bravo, Grace N Hibshman, et al. · Current Opinion in Biotechnology · 8
Publisher Correction: Structural basis for mismatch surveillance by CRISPR–Cas9
2022 · Jack P. K. Bravo, Mu-Sen Liu, et al. · Nature · 7
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Anti-plasmid immunity: a key to pathogen success?
2024 · Jack P K Bravo · Future Microbiology · 4
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Works count: 81
Citation count: 1,355
H-index: 20
I10-index: 22
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