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Isaac G. Sakala

Observed names: Isaac G Sakala, Isaac Sakala, Sakala, Isaac, Sakala, Isaac Gibson
Observed institutions: Australian National University, Flinders University, Washington University in St. Louis, Flinders Medical Centre, Vaxine (Australia), Australian Respiratory and Sleep Medicine Institute, Saint Louis University
ORCID: 0000-0002-7472-3864
Observed ORCID: 0000-0002-7472-3864
OpenAlex ID: A5033839836
Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells
2013 · Rangsima Reantragoon, Alexandra J. Corbett, et al. · The Journal of Experimental Medicine · 596
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Live and Inactivated Influenza Vaccines Induce Similar Humoral Responses, but Only Live Vaccines Induce Diverse T-Cell Responses in Young Children
2011 · Daniel F. Hoft, Elizabeth Babusis, et al. · The Journal of Infectious Diseases · 329
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Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites
2015 · Isaac G Sakala, Lars Kjer-Nielsen, et al. · The Journal of Immunology · 133
Granzyme A Produced by γ9δ2 T Cells Induces Human Macrophages to Inhibit Growth of an Intracellular Pathogen
2013 · Charles T. Spencer, Getahun Abate, et al. · PLoS Pathogens · 116
Poxvirus CD8+T-Cell Determinants and Cross-Reactivity in BALB/c Mice
2006 · David C. Tscharke, Wai-Ping Woo, et al. · Journal of Virology · 116
Highly conserved influenza T cell epitopes induce broadly protective immunity
2019 · Christopher S. Eickhoff, Frances E. Terry, et al. · Vaccine · 74
Influenza immunization during pregnancy: Benefits for mother and infant
2016 · Isaac G. Sakala, Yoshikazu Honda-Okubo, et al. · Human Vaccines & Immunotherapeutics · 72
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Optimizing vaccine development
2011 · Daniel F. Hoft, Vladimir Brusic, et al. · Cellular Microbiology · 38
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A Subset of Protective γ9δ2T Cells Is Activated by Novel Mycobacterial Glycolipid Components
2016 · Mei Xia, Danny C. Hesser, et al. · Infection and Immunity · 35
Poxvirus-Encoded Gamma Interferon Binding Protein Dampens the Host Immune Response to Infection
2007 · Isaac G. Sakala, Geeta Chaudhri, et al. · Journal of Virology · 35
Rapid Development of Analytical Methods for Evaluating Pandemic Vaccines: A Covid-19 Perspective
2021 · Jeremy Baldwin, Sakshi Piplani, et al. · Bioanalysis · 34
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Neonatal vaccine effectiveness and the role of adjuvants
2019 · Isaac G. Sakala, Katherine Marie Eichinger, et al. · Expert Review of Clinical Immunology · 31
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BBIQ, a pure TLR7 agonist, is an effective influenza vaccine adjuvant
2020 · Deepender Kaushik, Simran Dhingra, et al. · Human Vaccines & Immunotherapeutics · 28
A M2 protein-based universal influenza vaccine containing Advax-SM adjuvant provides newborn protection via maternal or neonatal immunization
2021 · Isaac G. Sakala, Yoshikazu Honda-Okubo, et al. · Vaccine · 22
Investigation of the biodistribution, breakdown and excretion of delta inulin adjuvant
2017 · Lixin Wang, Thomas Barclay, et al. · Vaccine · 20
Design and Synthesis of Polyphenolic Imidazo[4,5-c]quinoline Derivatives to Modulate Toll Like Receptor-7 Agonistic Activity and Adjuvanticity
2024 · Kushvinder Kumar, Binita Sihag, et al. · ACS Pharmacology & Translational Science · 18
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Combined delivery of TLR2 and TLR7 agonists by Nanostructured lipid carriers induces potent vaccine adjuvant activity in mice
2021 · Arshpreet Kaur, Rohini Kanwar, et al. · International Journal of Pharmaceutics · 18
Modulation of the Adjuvant Potential of Imidazoquinoline-Based TLR7/8 Agonists via Alum Adsorption
2024 · Kushvinder Kumar, Yoshikazu Honda-Okubo, et al. · ACS Medicinal Chemistry Letters · 17
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Structure–Activity Relationships toward the Identification of a High-Potency Selective Human Toll-like Receptor-7 Agonist
2024 · Deepender Kaushik, Arshpreet Kaur, et al. · Journal of Medicinal Chemistry · 17
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Stereoisomeric Pam 2 CS based TLR2 agonists: synthesis, structural modelling and activity as vaccine adjuvants
2022 · Arshpreet Kaur, Sakshi Piplani, et al. · RSC Medicinal Chemistry · 12
Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice
2015 · Isaac G. Sakala, Geeta Chaudhri, et al. · PLoS Pathogens · 12
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Dipterinyl Calcium Pentahydrate Inhibits Intracellular Mycobacterial Growth in Human Monocytes via the C-C Chemokine MIP-1β and Nitric Oxide
2013 · Isaac G. Sakala, Christopher S. Eickhoff, et al. · Infection and Immunity · 9
An Advax-CpG55.2 adjuvanted recombinant hemagglutinin vaccine provides immunity against H7N9 influenza in adult and neonatal mice
2023 · Yoshikazu Honda-Okubo, Isaac G. Sakala, et al. · Vaccine · 8
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Deficiency in Th2 Cytokine Responses Exacerbate Orthopoxvirus Infection
2015 · Isaac G. Sakala, Geeta Chaudhri, et al. · PLoS ONE · 8
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Developmental and reproductive safety of Advax-CpG55.2™ adjuvanted COVID-19 and influenza vaccines in mice
2023 · Isaac G. Sakala, Yoshikazu Honda-Okubo, et al. · Vaccine · 6
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Works count: 39
Citation count: 1,812
H-index: 17
I10-index: 21
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