Get started
Author

Craig Siegel

Observed names: C S Siegel, C Siegel, C. S. Siegel, C. SIEGEL, C. Siegel, CRAIG SIEGEL, Craig S. Siegel
ORCID: 0009-0002-1271-9613
Observed ORCID: 0009-0002-1271-9613
OpenAlex ID: A5033862468
Detailed Analysis of Structures and Formulations of Cationic Lipids for Efficient Gene Transfer to the Lung
1996 · Edward R. Lee, John Marshall, et al. · Human Gene Therapy · 445
Biophysical characterization of cationic lipid:DNA complexes
1997 · S.J Eastman, C Siegel, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 275
PDF
Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes
2007 · Hongmei Zhao, Malgorzata Przybylska, et al. · Diabetes · 238
PDF
A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease
2007 · Kerry Anne McEachern, John Fung, et al. · Molecular Genetics and Metabolism · 180
Efficacy of Enzyme and Substrate Reduction Therapy with a Novel Antagonist of Glucosylceramide Synthase for Fabry Disease
2015 · Karen M. Ashe, Eva Budman, et al. · Molecular Medicine · 107
PDF
Asymmetric aldol reactions. A titanium enolate giving very high diastereofacial selectivities
1989 · Craig Siegel, Edward R. Thornton · Journal of the American Chemical Society · 90
Optimization of Formulations and Conditions for the Aerosol Delivery of Functional Cationic Lipid:DNA Complexes
1997 · Simon J. Eastman, Jennifer D. Tousignant, et al. · Human Gene Therapy · 80
Novel Cannabinol Probes for CB1 and CB2 Cannabinoid Receptors
2000 · Anu Mahadevan, Craig Siegel, et al. · Journal of Medicinal Chemistry · 73
Lowering Glycosphingolipid Levels in CD4+ T Cells Attenuates T Cell Receptor Signaling, Cytokine Production, and Differentiation to the Th17 Lineage
2011 · Yunxiang Zhu, Nathan Gumlaw, et al. · Journal of Biological Chemistry · 59
PDF
Improved management of lysosomal glucosylceramide levels in a mouse model of type 1 Gaucher disease using enzyme and substrate reduction therapy
2010 · John Marshall, Kerry Anne McEachern, et al. · Journal of Inherited Metabolic Disease · 48
Cationic Lipid Structure and Formulation Considerations for Optimal Gene Transfection of the Lung
2000 · John Marshall, Jennifer B. Nietupski, et al. · Journal of drug targeting · 40
Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury
2015 · Y. Zou, M. Stagi, et al. · Journal of Neuroscience · 38
PDF
Very high diastereofacial selectivities in convenient titanium—mediated aldol reactions
1986 · Craig Siegel, Edward R. Thornton · Tetrahedron Letters · 38
Conformational model for asymmetric Diels-Alder reactions with chiral dienes
1988 · Craig Siegel, Edward R. Thornton · Tetrahedron Letters · 37
Synthesis of racemic and optically active .DELTA.9-tetrahydrocannabinol (THC) metabolites
1991 · Craig Siegel, Patrick M. Gordon, et al. · The Journal of Organic Chemistry · 35
Reducing glycosphingolipid biosynthesis in airway cells partially ameliorates disease manifestations in a mouse model of asthma
2010 · J. Karman, J. L. Tedstone, et al. · International Immunology · 33
Increased Hepatic Insulin Action in Diet-Induced Obese Mice Following Inhibition of Glucosylceramide Synthase
2010 · Nelson S. Yew, Hongmei Zhao, et al. · PLoS ONE · 32
PDF
Synthesis and pharmacological evaluation of ether and related analogs of .DELTA.8-, .DELTA.9-, and .DELTA.9,11-tetrahydrocannabinol
1991 · David R. Compton, W. Roy Prescott, et al. · Journal of Medicinal Chemistry · 31
An optically active terpenic synthon for .DELTA.9-cannabinoids: synthesis of (-)-11-hydroxy-.DELTA.9-tetrahydrocannabinol (THC) and its 1',1'-dimethylheptyl analog
1989 · Craig Siegel, Patrick M. Gordon, et al. · The Journal of Organic Chemistry · 21
Limitations of the Murine Nose in the Development of Nonviral Airway Gene Transfer
2009 · Uta Griesenbach, Stephanie G. Sumner-Jones, et al. · American Journal of Respiratory Cell and Molecular Biology · 20
Process Development of a GCS Inhibitor Including Demonstration of Lossen Rearrangement on Kilogram Scale
2015 · Jin Zhao, Rayomand Gimi, et al. · Organic Process Research & Development · 16
Diels-Alder reactions with dienes bearing a remote stereogenic center. Conformational model for diastereofacial selectivity
1991 · Craig Siegel, Edward R. Thomton · Tetrahedron Asymmetry · 12
Evaluation of Agonist-antagonist Properties of Nitrogen Mustard and Cyano Derivatives of Δ 8 -Tetrahydrocannabinol
1996 · JENNY L WILEY, DAVID R COMPTON, et al. · Neuropharmacology · 10
Studies on the Synthesis of (-)-11-Nor-9-carboxy-Δ9-Tetrahydrocannabinol (THC) and Related Compounds: An Improved Oxidative Procedure
1991 · Craig Siegel, Patrick M. Gordon, et al. · Synthesis · 8
Elovl1 inhibition reduced very long chain fatty acids in a mouse model of adrenoleukodystrophy
2025 · Jeremy Y. Huang, Brian Freed, et al. · iScience · 6
Works count: 40
Citation count: 1,987
H-index: 20
I10-index: 23
Year
Topic
Type