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Alejandro Sevilleja-Ortiz
Observed name:
A. Sevilleja-Ortiz
Institutions:
Universidad Francisco de Vitoria,
Instituto Ramón y Cajal de Investigación Sanitaria,
Hospital Universitario Ramón y Cajal
Observed institutions:
Universidad Francisco de Vitoria,
Instituto Ramón y Cajal de Investigación Sanitaria,
Hospital Universitario Ramón y Cajal
ORCID:
0000-0002-8521-2058
Observed ORCID:
0000-0002-8521-2058
OpenAlex ID:
A5034026844
Short-term pharmacological activation of Nrf2 ameliorates vascular dysfunction in aged rats and in pathological human vasculature. A potential target for therapeutic intervention
2019
·
Javier Angulo
, Mariam El Assar
, et al.
·
Redox Biology
·
58
PDF
Early manifestation of aging-related vascular dysfunction in human penile vasculature—A potential explanation for the role of erectile dysfunction as a harbinger of systemic vascular disease
2021
·
Mariam El Assar
, Javier Angulo
, et al.
·
GeroScience
·
28
Onion and Apple Functional Ingredients Intake Improves Antioxidant and Inflammatory Status and Vascular Injury in Obese Zucker Rats
2022
·
Claudia Balderas
, Javier Angulo
, et al.
·
Antioxidants
·
14
PDF
Erectile dysfunction is associated with defective L-cysteine/hydrogen sulfide pathway in human corpus cavernosum and penile arteries
2020
·
José M. La Fuente
, Alejandro Sevilleja-Ortiz
, et al.
·
European Journal of Pharmacology
·
12
Functional Role of STIM-1 and Orai1 in Human Microvascular Aging
2022
·
Mariam El Assar
, Esther García-Rojo
, et al.
·
Cells
·
10
PDF
Enhanced Contribution of Orai Channels to Contractility of Human Penile Smooth Muscle in Erectile Dysfunction
2020
·
Alejandro Sevilleja-Ortiz
, Mariam El Assar
, et al.
·
The Journal of Sexual Medicine
·
8
Upregulation of Orai Channels Contributes to Aging-Related Vascular Alterations in Rat Coronary Arteries
2023
·
Javier Angulo
, Argentina Fernández
, et al.
·
International Journal of Molecular Sciences
·
7
PDF
Ageing-induced hypercontractility is related to functional enhancement of STIM/Orai and upregulation of Orai 3 in rat and human penile tissue
2021
·
Alejandro Sevilleja-Ortiz
, Mariam El Assar
, et al.
·
Mechanisms of Ageing and Development
·
7
STIM/Orai Inhibition as a Strategy for Alleviating Diabetic Erectile Dysfunction Through Modulation of Rat and Human Penile Tissue Contractility andin vivoPotentiation of Erectile Responses
2022
·
Alejandro Sevilleja-Ortiz
, Mariam El Assar
, et al.
·
The Journal of Sexual Medicine
·
6
Orai1 Expression and Vascular Function in Kidney Donors Determine Graft Outcomes at Short/Mid-Term
2025
·
Esther García-Rojo
, Javier Angulo
, et al.
·
Cells
·
1
PDF
PS-3-1 Reduced Expression of Hydrogen Sulfide Synthesizing Enzymes Is Associated With the Functional Impairment of L-Cysteine-Induced Responses in Human Corpus Cavernosum and Penile Arteries From ED Patients
2020
·
J. Angulo
, A. Sevilleja-Ortiz
, et al.
·
The Journal of Sexual Medicine
·
1
PS-3-6 Orai Channel Inhibition Modulates Hypercontractility in Corpus Cavernosum From Diabetic Rats and Diabetic ED Patients where Orai Expression Is Upregulated
2020
·
J. Angulo
, A. Sevilleja-Ortiz
, et al.
·
The Journal of Sexual Medicine
Mp84-09 Defective L-cysteine/hydrogen Sulfide Pathway in Human Corpus Cavernosum and Penile Arteries From Men With Erectile Dysfunction
2020
·
Alejandro Sevilleja-Ortiz
, José M. La Fuente
, et al.
·
The Journal of Urology
PDF
Aging increases contribution of Orai channels to contractile tone in corpus cavernosum. Therapeutic potential in erectile dysfunction
2020
·
Alejandro Sevilleja-Ortiz
, Mariam El Assar
, et al.
·
Dianas
NRF-2 activation improves vascular dysfunction associated to aging in rats
2019
·
R.A. Torrado Carrión
, M. El Assar
, et al.
·
Clinica Chimica Acta
PS-04-001 Aging Increases Contribution of Orai Channels to Contractile Tone in Rat and Human Corpus Cavernosum
2019
·
J.A. Frutos
, M. El Assar
, et al.
·
The Journal of Sexual Medicine
018 Antagonizing Penile Smooth Muscle Contraction by Inhibition of Orai Calcium Channels. A Potential Therapeutic Target in Erectile Dysfunction
2018
·
J. Angulo
, M. El Assar
, et al.
·
The Journal of Sexual Medicine
Mp43-08 Inhibition of Penile Smooth Muscle Contraction by Blockade of Stim/orai Calcium Entry System as a Potential Strategy for Erectile Dysfunction
2018
·
Javier Romero-Otero
, javier Angulo
, et al.
·
The Journal of Urology
PDF
STIM/Orai calcium entry system contributes to contractility of human penile smooth muscle, becoming a potential therapeutic target in erectile dysfunction
2018
·
J. Romero Otero
, J. Angulo
, et al.
·
European Urology Supplements
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Works count:
19
Citation count:
152
H-index:
7
I10-index:
5
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