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Fabien Delaspre

First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass
2015 · Guangliang Wang, Surendra K Rajpurohit, et al. · eLife · 96
HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy
2017 · Antonella Mangraviti, Tula Raghavan, et al. · Scientific Reports · 93
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Centroacinar Cells Are Progenitors That Contribute to Endocrine Pancreas Regeneration
2015 · Fabien Delaspre, Rebecca L. Beer, et al. · Diabetes · 87
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PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia
2020 · Laura Rodríguez-Pascau, Elena Britti, et al. · Neurobiology of Disease · 62
Mitochondrial calcium signalling and neurodegenerative diseases
2018 · Elena Britti, Fabien Delaspre, et al. · Neuronal Signaling · 47
Frataxin‐deficient neurons and mice models of Friedreich ataxia are improved by TAT ‐ MTS cs‐ FXN treatment
2017 · Elena Britti, Fabien Delaspre, et al. · Journal of Cellular and Molecular Medicine · 43
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Mitochondrial pore opening and loss of Ca2+ exchanger NCLX levels occur after frataxin depletion
2017 · R. Purroy, E. Britti, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 39
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Retinoic acid plays an evolutionarily conserved and biphasic role in pancreas development
2014 · Wei Huang, Guangliang Wang, et al. · Developmental Biology · 39
The Ralstonia solanacearum pathogenicity regulator HrpB induces 3-hydroxy-oxindole synthesis
2007 · Fabien Delaspre, Carlos G. Nieto Peñalver, et al. · Proceedings of the National Academy of Sciences · 38
Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response
2024 · Arabela Sanz-Alcázar, Marta Portillo-Carrasquer, et al. · Redox Biology · 31
Mitochondrial iron and calcium homeostasis in Friedreich ataxia
2021 · Jordi Tamarit, Elena Britti, et al. · IUBMB Life · 27
Murine Embryonic Stem Cell–Derived Pancreatic Acinar Cells Recapitulate Features of Early Pancreatic Differentiation
2008 · Meritxell Rovira, Fabien Delaspre, et al. · Gastroenterology · 27
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Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia
2020 · Elena Britti, Fabien Delaspre, et al. · Biochemical Journal · 24
Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na+/Ca2+ Exchanger, NCLX, and Apoptosis
2020 · Elena Britti, Fabien Delaspre, et al. · Neurochemical Research · 24
Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models
2023 · Arabela Sanz-Alcázar, Elena Britti, et al. · Cellular and Molecular Life Sciences · 22
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Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations
2022 · Marta Medina-Carbonero, Arabela Sanz-Alcázar, et al. · Cellular and Molecular Life Sciences · 20
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Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation
2016 · Wei Huang, Rebecca L. Beer, et al. · Developmental Biology · 14
Directed Pancreatic Acinar Differentiation of Mouse Embryonic Stem Cells via Embryonic Signalling Molecules and Exocrine Transcription Factors
2013 · Fabien Delaspre, Mohammad Massumi, et al. · PLoS ONE · 14
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Calcitriol Treatment Is Safe and Increases Frataxin Levels in Friedreich Ataxia Patients
2024 · Berta Alemany‐Perna, Jordi Tamarit, et al. · Movement Disorders · 6
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Targeting frataxin deficiency in DRG neurons and fibroblasts: omaveloxolone restores metabolic and iron balance to reduce ferroptosis
2026 · Marta Portillo-Carrasquer, Arabela Sanz-Alcázar, et al. · Biomedicine & Pharmacotherapy · 5
Leriglitazone improves iron homeostasis and ferroptotic markers in frataxin-deficient dorsal root ganglia neurons
2025 · Marta Portillo-Carrasquer, Arabela Sanz-Alcázar, et al. · Biomedicine & Pharmacotherapy · 5
Pathological frataxin deficiency in mice causes tissue-specific alterations in iron homeostasis
2026 · Maria Pazos-Gil, Marta Medina-Carbonero, et al. · iScience · 4
Deficient Mitochondrial Respiration Impairs Sirtuin Activity in Dorsal Root Ganglia in Friedreich Ataxia Mouse and Cell Models
2023 · Arabela Sanz-Alcázar, Elena Britti, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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Evolution of an Iron-Detoxifying Protein: Eukaryotic and Rickettsia Frataxins Contain a Conserved Site Which Is Not Present in Their Bacterial Homologues
2022 · Rui Alves, Maria Pazos-Gil, et al. · International Journal of Molecular Sciences · 2
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Biochemical alterations precede neurobehavioral deficits in a novel mouse model of Friedreich ataxia
2021 · Marta Medina-Carbonero, Arabela Sanz-Alcázar, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Works count: 34
Citation count: 773
H-index: 16
I10-index: 18
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