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Author

Mahmoud Elshal

Institution: Mansoura University
ORCID: 0000-0002-9528-7483
Observed ORCID: 0000-0002-9528-7483
OpenAlex ID: A5034112618
Preventive empagliflozin activity on acute acetic acid-induced ulcerative colitis in rats via modulation of SIRT-1/PI3K/AKT pathway and improving colon barrier
2022 · Marwa S. Zaghloul, Mahmoud Elshal, et al. · Environmental Toxicology and Pharmacology · 54
Escin suppresses immune cell infiltration and selectively modulates Nrf2/HO-1, TNF-α/JNK, and IL-22/STAT3 signaling pathways in concanavalin A-induced autoimmune hepatitis in mice
2022 · Mahmoud Elshal, Sara H. Hazem · Inflammopharmacology · 34
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Diacerein counteracts acetaminophen-induced hepatotoxicity in mice via targeting NLRP3/caspase-1/IL-1β and IL-4/MCP-1 signaling pathways
2022 · Mahmoud Elshal, Marwa E. Abdelmageed · Archives of Pharmacal Research · 28
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Targeting SIRT1/AMPK/Nrf2/NF-кB by sitagliptin protects against oxidative stress-mediated ER stress and inflammation during ANIT-induced cholestatic liver injury
2024 · Rami M. Mosaoa, Mohammed W. Al-Rabia, et al. · Toxicology · 25
Retinoic acid modulates IL-4, IL-10 and MCP-1 pathways in immune mediated hepatitis and interrupts CD4+ T cells infiltration
2019 · Mahmoud Elshal, Nashwa Abu-Elsaad, et al. · International Immunopharmacology · 24
The multi-kinase inhibitor pazopanib targets hepatic stellate cell activation and apoptosis alleviating progression of liver fibrosis
2015 · Mahmoud Elshal, Nashwa Abu-Elsaad, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 21
Inhibitory effect of diacerein on diclofenac-induced acute nephrotoxicity in rats via modulating SIRT1/HIF-1α/NF-κB and SIRT1/p53 regulatory axes
2024 · Abduallah Nasser Mansoure, Mahmoud Elshal, et al. · International Immunopharmacology · 19
Modulation of the crosstalk between Keap1/Nrf2/HO-1 and NF-κB signaling pathways by Tomatidine protects against inflammation/oxidative stress-driven fulminant hepatic failure in mice
2024 · Wesam H. Abdulaal, Ulfat M. Omar, et al. · International Immunopharmacology · 19
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents
2023 · Mohammad M. Al-Sanea, Abdelrahman Hamdi, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 19
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Pirfenidone ameliorates ANIT-induced cholestatic liver injury via modulation of FXR, NF-кB/TNF-α, and Wnt/GSK-3β/β-catenin signaling pathways
2024 · Wesam H. Abdulaal, Ulfat M. Omar, et al. · Toxicology and Applied Pharmacology · 18
Targeting Nrf2/HO-1 and NF-κB/TNF-α signaling pathways with empagliflozin protects against atrial fibrillation-induced acute kidney injury in rats
2024 · Hussein Badreldin, Amr El-Karef, et al. · Toxicology · 16
Bioactivity of Eriocephalus africanus essential oil against concanavalin A-induced hepatitis via suppressing immune cell infiltration, inhibiting TNF-α/NF-κB and IFN-γ/STAT1 signaling pathways
2023 · Abdullah Haikal, Amal A. Galala, et al. · Journal of Ethnopharmacology · 14
Relative Importance of Different Elements of Mitochondrial Oxidative Phosphorylation in Maintaining the Barrier Integrity of Retinal Endothelial Cells: Implications for Vascular-Associated Retinal Diseases
2022 · Shaimaa Eltanani, Thangal Yumnamcha, et al. · Cells · 14
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Etanercept attenuates immune-mediated hepatitis induced by concanavalin A via differential regulation of the key effector cytokines of CD4+ T cells
2021 · Mahmoud Elshal, Nashwa Abu-Elsaad, et al. · Life Sciences · 12
Renoprotective effect of diacetylrhein on diclofenac-induced acute kidney injury in rats via modulating Nrf2/NF-κB/NLRP3/GSDMD signaling pathways
2024 · Abduallah Nasser Mansoure, Mahmoud Elshal, et al. · Food and Chemical Toxicology · 11
Empagliflozin protects the heart from atrial fibrillation in rats through inhibiting the NF-κB/HIF-1α regulatory axis and atrial remodeling
2024 · Hussein Badreldin, Mahmoud Elshal, et al. · International Immunopharmacology · 10
Urolithin B as a renoprotective agent against 5-fluorouracil-induced nephrotoxicity: Role of Nrf2/Keap1/HO-1, SIRT1/FOXO3, and NF-кB/TNF-α signaling pathways
2024 · Mohammed W. Al-Rabia, Hani Z. Asfour, et al. · Food and Chemical Toxicology · 8
Attenuating amiodarone-induced lung toxicity by the vitamin D receptor activator paricalcitol in rats: targeting TLR4/NF-κB/HIF-1α and TGF-β/Smad signaling pathways
2025 · Aamal G. El-Waseif, Mahmoud Elshal, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 3
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Paricalcitol, an active vitamin D analog, mitigates dexamethasone-induced hepatic injury: Role of autophagy, pyroptosis, and PERK/Nrf2/HO-1 signaling pathway
2025 · Aamal G. El-Waseif, Mahmoud Elshal, et al. · Toxicology and Applied Pharmacology · 3
Trientine ameliorates bleomycin-induced pulmonary fibrosis in rats through copper chelation and modulation of the CTR1/LOX/COL pathway
2026 · Ibrahim T. Khalil, Mahmoud Elshal, et al. · Inflammopharmacology · 2
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Targeting the underlying immune mechanism of diabetes-induced myocardial dysfunction via modulation of SIRT-3/p53/TIGAR/PFKFB-3 and SIRT-3/NF-κB signaling pathways as a potential controlling strategy
2026 · Mohamed S. Elsayed, Mahmoud Elshal, et al. · Biomedicine & Pharmacotherapy · 2
The AURKA-Selective Inhibitor Alisertib Attenuates Doxorubicin-Induced Hepatotoxicity in Mice via Modulation of IL-17A/NF-κB and STAT3 Signaling Pathways
2025 · Faisal Alqussair, Mahmoud Elshal, et al. · Pharmaceuticals · 2
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The Gut Microbiota Metabolite Urolithin B Mitigates Cholestatic Liver Injury in Mice via Modulating the Crosstalk Between PPARα, Nrf2, and NF-κB Signaling Pathways
2025 · Hani M. Alrawili, Mahmoud Elshal, et al. · Journal of Xenobiotics · 2
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3,4-Dimethoxycinnamic acid from coffee silverskin biowaste ameliorates bleomycin-induced pulmonary fibrosis via modulating caveolin-1-dependent activation of NF-κB, TGF-β1/Smad3, and ERK1/2 signaling pathways
2025 · Mahmoud Elshal, Abdelrahman Hamdi, et al. · Toxicology and Applied Pharmacology · 2
Honokiol Ameliorates LPS/D-GalN-Induced Acute Liver Failure via Activation of SIRT3/AMPK and Keap1/Nrf2/HO-1 Signaling and Inhibition of the NF-κB/NLRP3 Inflammasome Axis
2026 · Abdulaziz F. Alhussaini, Mahmoud Elshal, et al. · Pharmaceuticals · 1
Works count: 34
Citation count: 362
H-index: 13
I10-index: 15
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