Author

Melanie E Sumner

Observed name: Melanie Sumner

Institution: AiCuris (Germany)

Observed institutions: AiCuris (Germany), Heinrich Heine University Düsseldorf

ORCID: 0009-0009-0205-4970

Observed ORCID: 0009-0009-0205-4970

OpenAlex ID: A5034137042

Discovery, Chemistry, and Preclinical Development of Pritelivir, a Novel Treatment Option for Acyclovir-Resistant Herpes Simplex Virus Infections

2022 · Alexander Birkmann, Susanne Bonsmann, et al. · Journal of Medicinal Chemistry · 60

First‐in‐Human, Single‐ and Multiple‐Ascending‐Dose, Food‐Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase‐Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects

2023 · Dirk Kropeit, Susanne Bonsmann, et al. · Clinical Pharmacology in Drug Development · 19

A Multicenter Assessment of the Outcomes and Toxicities of Foscarnet for Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex in Immunocompromised Patients

2024 · Sarah P Hammond, Manickam Rangaraju, et al. · Open Forum Infectious Diseases · 13

Mass Balance and Metabolite Profile after Single and Multiple Oral Doses of Pritelivir in Healthy Subjects

2024 · Susanne Bonsmann, David McCormick, et al. · Clinical Pharmacology in Drug Development · 10

Evaluation of the Clinical Drug‐Drug Interaction Potential of Pritelivir on Transporters and CYP450 Enzymes Using a Cocktail Approach

2024 · Michiel de Vries, Susanne Bonsmann, et al. · Clinical Pharmacology in Drug Development · 6

Efficacy and Safety of Pritelivir vs Foscarnet for the Treatment of Acyclovir-Refractory Herpes Simplex Virus Infection in Immunocompromised Adults: A Randomized, Open-Label Phase 2 Trial

2026 · Camille N Kotton, Kimberly A Workowski, et al. · Open Forum Infectious Diseases · 1

233. Efficacy and safety results from the Phase 2 clinical trial of pritelivir versus foscarnet for treatment of acyclovir-refractory and/or resistant mucocutaneous HSV infections in immunocompromised subjects

2026 · Camille N Kotton, Robin K Avery, et al. · Open Forum Infectious Diseases · 1

Effect of Renal and Hepatic Impairment on the Pharmacokinetics of Pritelivir and Its Metabolites

2024 · Katharina Erb‐Zohar, Susanne Bonsmann, et al. · Clinical Pharmacology in Drug Development · 1

Treatment of Herpes simplex encephalitis with the helicase-primase inhibitor pritelivir in an immunocompromised patient

2026 · Catherina Lueck, Christina Rautenberg, et al. · npj Antimicrobials and Resistance

[Drug interactions of tacrolimus].

2006 · Melanie E Sumner, Stefanie Albers, et al. · PubMed

Works count: 10

Citation count: 111

H-index: 5

I10-index: 4