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Brian K. Raymer

Observed names: B. Raymer, Brian Raymer, Raymer, Brian
ORCID: 0000-0003-3913-5327
Observed ORCID: 0000-0003-3913-5327
OpenAlex ID: A5034603441
Total Synthesis of (+)-Azaspiracid-1. An Exhibition of the Intricacies of Complex Molecule Synthesis
2008 · David A. Evans, Lisbet Kværnø, et al. · Journal of the American Chemical Society · 102
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose
2020 · Kentaro Futatsugi, Aaron C. Smith, et al. · Journal of Medicinal Chemistry · 86
Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK)
2017 · Kim Huard, Kay Ahn, et al. · Journal of Medicinal Chemistry · 55
Total Synthesis of (+)‐Azaspiracid‐1. Part II: Synthesis of the EFGHI Sulfone and Completion of the Synthesis
2007 · David A. Evans, Travis B. Dunn, et al. · Angewandte Chemie International Edition · 55
Lead-like Drugs: A Perspective
2018 · Brian Raymer, Samit K. Bhattacharya · Journal of Medicinal Chemistry · 52
Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis
2017 · Kim F. McClure, David W. Piotrowski, et al. · Angewandte Chemie International Edition · 46
Total Synthesis of (+)‐Azaspiracid‐1. Part I: Synthesis of the Fully Elaborated ABCD Aldehyde
2007 · David A. Evans, Lisbet Kværnø, et al. · Angewandte Chemie International Edition · 44
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss
2023 · Michelle R. Garnsey, Aaron C. Smith, et al. · Journal of Medicinal Chemistry · 35
Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase
2009 · Brian Raymer, Michael Kavana, et al. · Bioorganic & Medicinal Chemistry Letters · 16
Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/piperazine-1-carboxamides as small molecule inhibitors of PCSK9
2018 · Allyn T. Londregan, Gary Aspnes, et al. · Bioorganic & Medicinal Chemistry Letters · 14
Total Synthesis of (+)‐Azaspiracid‐1. Part I: Synthesis of the Fully Elaborated ABCD Aldehyde
2007 · David A. Evans, Lisbet Kværnø, et al. · Angewandte Chemie · 13
Total Synthesis of (+)‐Azaspiracid‐1. Part II: Synthesis of the EFGHI Sulfone and Completion of the Synthesis
2007 · David A. Evans, Travis B. Dunn, et al. · Angewandte Chemie · 11
Sleep modulating agents
2019 · Younggi Choi, Brian K. Raymer · Bioorganic & Medicinal Chemistry Letters · 7
Small molecule and peptide therapies for chronic heart failure: a patent review (2011 – 2014)
2015 · Brian Raymer, David Ebner · Expert Opinion on Therapeutic Patents · 6
Small molecule inhibitors of PCSK9. SAR investigations of head and amine groups
2023 · Gary E. Aspnes, Steven B. Coffey, et al. · Bioorganic & Medicinal Chemistry Letters · 4
Liver‐Targeted Small‐Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis
2017 · Kim F. McClure, David W. Piotrowski, et al. · Angewandte Chemie · 4
Synthesis of (+)-Azaspiracid-1
2007 · D. A. Evans, T. B. Dunn, et al. · Synfacts · 2
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0848 Evaluation of the Novel Orexin 2 Receptor Agonist ALKS 2680 on Measures of Arousal Circuit Activation in Rodents
2025 · Julie Brooks, Angelica Patino, et al. · SLEEP
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Evaluation of a novel, orally available orexin 2 receptor agonist, on wakefulness and cataplexy in a mouse model of Type 1 narcolepsy
2024 · J. Brooks, Y. Sun, et al. · Sleep Medicine
CCDC 2237356: Experimental Crystal Structure Determination
2023 · Garnsey, Michelle R., Smith, Aaron C., et al. · The Cambridge Structural Database
CCDC 2098502: Experimental Crystal Structure Determination
2021 · Futatsugi, Kentaro, Smith, Aaron C., et al. · The Cambridge Structural Database
CCDC 1858283: Experimental Crystal Structure Determination
2018 · Londregan, Allyn T., Aspnes, Gary, et al. · The Cambridge Structural Database
CCDC 1569471: Experimental Crystal Structure Determination
2017 · McClure, Kim F., Piotrowski, David W., et al. · The Cambridge Structural Database
CCDC 1569467: Experimental Crystal Structure Determination
2017 · McClure, Kim F., Piotrowski, David W., et al. · The Cambridge Structural Database
CCDC 1569460: Experimental Crystal Structure Determination
2017 · McClure, Kim F., Piotrowski, David W., et al. · The Cambridge Structural Database
Works count: 30
Citation count: 552
H-index: 11
I10-index: 12
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