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Lisa K. Folkes

Biological Consequences of Radiation-induced DNA Damage: Relevance to Radiotherapy
2013 · M.E. Lomax, L.K. Folkes, et al. · Clinical Oncology · 738
Kinetics and Mechanisms of Hypochlorous Acid Reactions
1995 · Lisa K. Folkes, Luis P. Candeias, et al. · Archives of Biochemistry and Biophysics · 357
Increased global transcription activity as a mechanism of replication stress in cancer
2016 · Panagiotis Kotsantis, Lara Marques Silva, et al. · Nature Communications · 336
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Phase I Clinical Trial of Weekly Combretastatin A4 Phosphate: Clinical and Pharmacokinetic Results
2003 · Gordon J.S. Rustin, Susan M. Galbraith, et al. · Journal of Clinical Oncology · 307
The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
2016 · Thomas M. Ashton, Emmanouil Fokas, et al. · Nature Communications · 248
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Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial
2018 · Paul C Lyon, Michael D Gray, et al. · The Lancet Oncology · 234
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Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest
2010 · Sebastián Carballal, Madia Trujillo, et al. · Free Radical Biology and Medicine · 221
Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability
2010 · Isabel M. Pires, Zuzana Bencokova, et al. · Cancer Research · 200
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Oxidative activation of indole-3-acetic acids to cytotoxic species— a potential new role for plant auxins in cancer therapy11Abbreviations: IAA, indole-3-acetic acid; HRP, horseradish peroxidase; TBA, thiobarbituric acid; MPO, myeloperoxidase; MOI, 3-methylene-2-oxindole; BSO, buthionine sulphoximine; GSH, glutathione; CEA, carcinoembryonic antigen; ADEPT, antibody directed enzyme prodrug therapy; PDEPT, polymer directed enzyme prodrug therapy; GDEPT, gene directed enzyme prodrug therapy; and PEG, polyethylene glycol.
2001 · Lisa K. Folkes, Peter Wardman · Biochemical Pharmacology · 166
Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial
2019 · Michael D. Gray, Paul C. Lyon, et al. · Radiology · 107
Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit
2008 · Edyta Madej, Lisa K. Folkes, et al. · Free Radical Biology and Medicine · 105
5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: phase I clinical and pharmacokinetic study
2003 · G J S Rustin, C Bradley, et al. · British Journal of Cancer · 105
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Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study
2007 · Quan-Sing Ng, Vicky Goh, et al. · The Lancet Oncology · 101
Free-Radical Repair by a Novel Perthiol: Reversible Hydrogen Transfer and Perthiyl Radical Formation
1994 · S. A. Everett, L. K. Folkes, et al. · Free Radical Research · 101
Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
2021 · Michael Skwarski, Daniel R. McGowan, et al. · Clinical Cancer Research · 94
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Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid
2000 · Olga Greco, Lisa K Folkes, et al. · Cancer Gene Therapy · 85
CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes
2016 · Liam J. O’Connor, Ishna N. Mistry, et al. · ACS Central Science · 80
Enhancement of Lipid Peroxidation by Indole-3-Acetic Acid and Derivatives: Substituent Effects
1995 · Luis P. Candeias, Lisa K. Folkes, et al. · Free Radical Research · 80
A Phase I Trial of Radioimmunotherapy with 131I-A5B7 Anti-CEA Antibody in Combination with Combretastatin-A4-Phosphate in Advanced Gastrointestinal Carcinomas
2009 · Tim Meyer, Andrew M. Gaya, et al. · Clinical Cancer Research · 76
Phase I Clinical and Pharmacokinetic Evaluation of the Vascular-Disrupting Agent OXi4503 in Patients with Advanced Solid Tumors
2012 · Dan M. Patterson, Martin Zweifel, et al. · Clinical Cancer Research · 75
Kinetics of reduction of tyrosine phenoxyl radicals by glutathione
2010 · Lisa K. Folkes, Madia Trujillo, et al. · Archives of Biochemistry and Biophysics · 74
Enhancing the efficacy of photodynamic cancer therapy by radicals from plant auxin (indole-3-acetic acid).
2003 · Lisa K Folkes, Peter Wardman · PubMed · 70
Peroxidase-catalyzed effects of indole-3-acetic acid and analogues on lipid membranes, DNA, and mammalian cells in vitro
1999 · Lisa K Folkes, Madeleine F Dennis, et al. · Biochemical Pharmacology · 67
Oxidative Metabolism of Combretastatin A-1 Produces Quinone Intermediates with the Potential To Bind to Nucleophiles and To Enhance Oxidative Stress via Free Radicals
2007 · Lisa K. Folkes, Martin Christlieb, et al. · Chemical Research in Toxicology · 65
Radiosensitization by Nitric Oxide at Low Radiation Doses
2007 · Peter Wardman, Kai Rothkamm, et al. · Radiation Research · 61
Works count: 95
Citation count: 5,343
H-index: 39
I10-index: 61
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