Author

Patrick Appiah‐Kubi

Observed names: Appiah-Kubi, Patrick, Appiah-Kubi, Patrick., P. Appiah-Kubi, Patrick A. Kubi, Patrick Appiah-Kubi

Institution: University of Pretoria

Observed institutions: University of Pretoria, University of KwaZulu-Natal

ORCID: 0000-0002-5904-3051

Observed ORCID: 0000-0002-5904-3051

OpenAlex ID: A5035650262

Computational modelling of potent β-secretase (BACE1) inhibitors towards Alzheimer's disease treatment

2020 · Samuel C. Ugbaja, Zainab K. Sanusi, et al. · Biophysical Chemistry · 22

Unravelling the molecular basis of AM-6494 high potency at BACE1 in Alzheimer’s disease: an integrated dynamic interaction investigation

2021 · Samuel C. Ugbaja, Patrick Appiah-Kubi, et al. · Journal of Biomolecular Structure and Dynamics · 11

Same Target, Different Therapeutic Outcomes: The Case of CAY10471 and Fevipiprant on CRTh2 Receptor in Treatment of Allergic Rhinitis and Asthma

2019 · Abdul R. Issahaku, Clement Agoni, et al. · Combinatorial Chemistry & High Throughput Screening · 11

Unveiling the Inhibitory Potentials of Peptidomimetic Azanitriles and Pyridyl Esters towards SARS-CoV-2 Main Protease: A Molecular Modelling Investigation

2023 · Aganze G. Mushebenge, Samuel C. Ugbaja, et al. · Molecules · 10

Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs

2016 · Patrick Appiah-Kubi, Mahmoud Soliman · Cell Biochemistry and Biophysics · 10

Dual anti-inflammatory and selective inhibition mechanism of leukotriene A4hydrolase/aminopeptidase: insights from comparative molecular dynamics and binding free energy analyses

2015 · Patrick Appiah-Kubi, Mahmoud E.S. Soliman · Journal of Biomolecular Structure and Dynamics · 10

Structural Investigations and Binding Mechanisms of Oseltamivir Drug Resistance Conferred by the E119V Mutation in Influenza H7N9 Virus

2022 · Samuel C. Ugbaja, Sphamandla E. Mtambo, et al. · Molecules · 9

Probing Binding Landscapes and Molecular Recognition Mechanisms of Atypical Antipsychotic Drugs towards the Selective Targeting of D2 Dopamine Receptor

2019 · Patrick Appiah‐Kubi, Fisayo Andrew Olotu, et al. · Molecular Informatics · 7

A Synergistic Combination Against Chronic Myeloid Leukemia: An Intra-molecular Mechanism of Communication in BCR–ABL1 Resistance

2019 · Ahmed A. El Rashedy, Patrick Appiah-Kubi, et al. · The Protein Journal · 6

Exploring the structural basis and atomistic binding mechanistic of the selective antagonist blockade at D3 dopamine receptor over D2 dopamine receptor

2021 · Patrick Appiah‐Kubi, Fisayo Andrew Olotu, et al. · Journal of Molecular Recognition · 4

Structure-based identification of novel scaffolds as potential HIV-1 entry inhibitors involving CCR5

2021 · Patrick Appiah-Kubi, Emmanuel Amarachi Iwuchukwu, et al. · Journal of Biomolecular Structure and Dynamics · 2

Withdrawal Notice: Elucidating the Disparate Inhibitory Mechanisms of Novel 1-Heteroaryl-1,3-Propanediamine Derivatives and Maraviroc towards C-C Chemokine Receptor 5: Insights for Structural Modifications in HIV-1 Drug Discovery

2020 · Patrick Appiah-Kubi, Fisayo Andrew Olotu, et al. · Medicinal Chemistry · 1

Stacked ensemble learning and in-silico profiling reveal dual DPP-IV and SGLT2 inhibitors from Moringa oleifera metabolites

2026 · M. K. Letuku, M. G. Mohlala, et al. · Scientific Reports

Coupling of HSP72 α-Helix Subdomains by the Unexpected Irreversible Targeting of Lysine-56 over Cysteine-17; Coevolution of Covalent Bonding

2020 · Aimen Aljoundi, Ahmed El Rashedy, et al. · Molecules

Works count: 18

Citation count: 105

H-index: 7

I10-index: 6