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Lucas de Almeida Machado

A machine learning-based virtual screening for natural compounds capable of inhibiting the HIV-1 integrase
2022 · Lucas A. Machado, Eduardo Krempser, et al. · Frontiers in Drug Discovery · 18
Cross-reactivity and immunotherapeutic potential of BamA recombinant protein from Acinetobacter baumannii
2021 · Anna Erika Vieira de Araujo, Luis Vidal Conde, et al. · Microbes and Infection · 18
Serine proteases profiles of Leishmania (Viannia) braziliensis clinical isolates with distinct susceptibilities to antimony
2021 · Anabel Zabala-Peñafiel, Geovane Dias-Lopes, et al. · Scientific Reports · 14
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Raltegravir-Induced Adaptations of the HIV-1 Integrase: Analysis of Structure, Variability, and Mutation Co-occurrence
2019 · Lucas de Almeida Machado, Marcelo Ferreira da Costa Gomes, et al. · Frontiers in Microbiology · 10
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Benchmarking Machine Learning Models for HIV-1 Protease Inhibitor Resistance Prediction: Impact of Data Set Construction and Feature Representation
2025 · Rocío Lucía Beatriz Riveros Maidana, Lucas de Almeida Machado, et al. · Journal of Chemical Information and Modeling · 9
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Evidence for Disruption of Mg2+ Pair as a Resistance Mechanism Against HIV-1 Integrase Strand Transfer Inhibitors
2020 · Lucas de Almeida Machado, Ana Carolina Ramos Guimarães · Frontiers in Molecular Biosciences · 6
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Engineering Protein Dynamics through Mutational Energy Landscape Traps
2025 · Lucas de Almeida Machado, João Sartori, et al. · Journal of Chemical Information and Modeling · 2
M. bovis BCG Moreau N-Terminal Loss Leads to a Less Stable Dodecin With Lower Flavin Binding Capacity
2021 · Marcos Gustavo Araujo Schwarz, Bianca Gallart Cinelli Luzes, et al. · Frontiers in Cellular and Infection Microbiology · 2
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Towards improved missense variant prioritization through automated structure-assisted interpretation
2026 · Nathália P.D. de Nigro, Paula F.C. Franklin, et al. · BMC Bioinformatics
Interrogating the contextual dependencies of ESM-2
2026 · Machado, Lucas · Zenodo (CERN European Organization for Nuclear Research)
A novel benchmark dataset for enzyme function prediction reveals the limitations of state-of-the-art models
2026 · João Sartori, Ana Carolina Ramos Guimarães, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Inherited IFNAR1 structural deficiency in severe adverse events following yellow fever vaccination
2026 · Tamiris Azamor, Paul Bastard, et al. · Clinical Immunology
Improving genomic annotation decision with structural-assisted variant interpretation
2026 · Nathália Nigro, Paula Franklin, et al. · International Symposium on Immunobiologicals (ISI)
A Genetic Algorithm to scour protein sequence space: A novel framework for protein engineering using protein language models and force fields
2025 · João Sartori, Eduardo Krempser, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Genetic Variants Affect Distinct Metabolic Pathways in Pediatric Multisystem Inflammatory Syndrome and Severe COVID‐19
2025 · Alysson Henrique Urbanski, Flávia Cristina de Paula Freitas, et al. · Journal of Medical Virology
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Design Strategies for Optimizing the Binding of an Α-Helical Peptide Binder While Preserving Secondary Structure
2024 · João Sartori, Paula Fernandes da Costa Franklin, et al. · SSRN Electronic Journal
Mechanistic Explanations for the Effects of Human N-Acetyltransferase 2 Mutations G51v, I114t and R197q
2023 · Lucas de Almeida Machado, Eloah Aguiar Soares da Silva, et al. · SSRN Electronic Journal
In silico studies of the HIV-1 integrase: mutational patterns, resistance mechanisms, and strategies to search for new drug candidates
2020 · Machado, Lucas de Almeida · Arca - Repositório Institucional da Fiocruz
Modelagem estatística do fenômeno de troca hidrogênio/deutério em proteínas através de propriedades estruturais e dinâmicas
2016 · Lucas de Almeida Machado · Americanae (AECID Library)
Works count: 20
Citation count: 79
H-index: 6
I10-index: 4
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